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- Peptide_hormone abstract "Peptide hormones are proteins that have endocrine functions in living animals.Like other proteins, peptide hormones are synthesized in cells from amino acids according to mRNA transcripts, which are synthesized from DNA templates inside the cell nucleus. Preprohormones, peptide hormone precursors, are then processed in several stages, typically in the endoplasmic reticulum, including removal of the N-terminal signal sequence and sometimes glycosylation, resulting in prohormones. The prohormones are then packaged into membrane-bound secretory vesicles, which can be secreted from the cell by exocytosis in response to specific stimuli (e.g. --an increase in Ca2+ and cAMP concentration in cytoplasm).These prohormones often contain superfluous amino acid residues that were needed to direct folding of the hormone molecule into its active configuration but have no function once the hormone folds. Specific endopeptidases in the cell cleave the prohormone just before it is released into the bloodstream, generating the mature hormone form of the molecule. Mature peptide hormones then travel through the blood to all of the cells of the body, where they interact with specific receptors on the surfaces of their target cells. Some peptide/protein hormones (angiotensin II, basic fibroblast growth factor-2, parathyroid hormone-related protein) also interact with intracellular receptors located in the cytoplasm or nucleus by an intracrine mechanism.".
- Peptide_hormone wikiPageID "248372".
- Peptide_hormone wikiPageRevisionID "603850826".
- Peptide_hormone hasPhotoCollection Peptide_hormone.
- Peptide_hormone subject Category:Peptide_hormones.
- Peptide_hormone subject Category:Proteins.
- Peptide_hormone type Abstraction100002137.
- Peptide_hormone type BodySubstance105263850.
- Peptide_hormone type Hormone105407119.
- Peptide_hormone type LiquidBodySubstance105397468.
- Peptide_hormone type Matter100020827.
- Peptide_hormone type Part113809207.
- Peptide_hormone type PeptideHormones.
- Peptide_hormone type PhysicalEntity100001930.
- Peptide_hormone type Relation100031921.
- Peptide_hormone type Secretion105404728.
- Peptide_hormone type Substance100019613.
- Peptide_hormone comment "Peptide hormones are proteins that have endocrine functions in living animals.Like other proteins, peptide hormones are synthesized in cells from amino acids according to mRNA transcripts, which are synthesized from DNA templates inside the cell nucleus. Preprohormones, peptide hormone precursors, are then processed in several stages, typically in the endoplasmic reticulum, including removal of the N-terminal signal sequence and sometimes glycosylation, resulting in prohormones.".
- Peptide_hormone label "Hormona peptídica".
- Peptide_hormone label "Hormone peptidique".
- Peptide_hormone label "Hormony peptydowe".
- Peptide_hormone label "Peptide hormone".
- Peptide_hormone label "Peptidehormoon".
- Peptide_hormone label "Proteohormone".
- Peptide_hormone label "ペプチドホルモン".
- Peptide_hormone label "肽类激素".
- Peptide_hormone sameAs Proteohormone.
- Peptide_hormone sameAs Hormona_peptídica.
- Peptide_hormone sameAs Hormone_peptidique.
- Peptide_hormone sameAs ペプチドホルモン.
- Peptide_hormone sameAs Peptidehormoon.
- Peptide_hormone sameAs Hormony_peptydowe.
- Peptide_hormone sameAs m.01kxvp.
- Peptide_hormone sameAs Q416997.
- Peptide_hormone sameAs Q416997.
- Peptide_hormone sameAs Peptide_hormone.
- Peptide_hormone wasDerivedFrom Peptide_hormone?oldid=603850826.
- Peptide_hormone isPrimaryTopicOf Peptide_hormone.