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- Periventricular_leukomalacia abstract "Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder. Affected individuals generally exhibit motor control problems or other developmental delays, and they often develop cerebral palsy or epilepsy later in life.This pathology of the brain was described under various names ("encephalodystrophy", "ischemic necrosis," "periventricular infarction", "coagulation necrosis", "leukomalacia," "softening of the brain," "infarct periventricular white matter", "necrosis of white matter", "diffuse symmetrical periventricular leukoencephalopathy"), and more often by German scientists, but the worldwide dissemination was the term «periventricular leukomalacia», introduced in 1962 B.A.Banker and J.C.Larroche. The term is not clear, since there are no softening of PVL, and more dense than surrounding areas of the brain foci of coagulation necrosis. V.V. Vlasyuk and V.P. Tumanov in 1985 published the world's first monograph devoted to PVL. The most comprehensive study of PVL in the world at the largest section material held V.V. Vlasyuk (1981) (frequency, etiopathogenesis, topography, degree of damage different parts of the brain, developmental stage lesions, histoneurology, the role of microglia, electron microscopy, histochemistry, and others), who first revealed the high incidence of optic radiation lesions and demonstrated that PVL - a persistent process that the old necrosis can join a new, foci of PVL may be at different stages of development. In the process of morphogenesis focuses PVL pass through three stages: 1) necrosis, 2) resorption, and 3) the formation gliosis scars or cysts. Cysts occur when large and confluent focuses of PVL, with mixed necrosis (kollikvacia in the center and coagulation rim at the periphery). Around the foci is generally defined area of other lesions of the brain white matter - the death of prooligodendrocytes, proliferation mikrogliocytes and astrocytes, swelling, bleeding, loss of capillaries, and others (the so-called "diffuse component PVL"). However, diffuse lesions without necrosis are not PVL.".
- Periventricular_leukomalacia diseasesdb "9868".
- Periventricular_leukomalacia emedicineSubject "ped".
- Periventricular_leukomalacia emedicineTopic "1773".
- Periventricular_leukomalacia icd10 "P91.2".
- Periventricular_leukomalacia icd9 "779.7".
- Periventricular_leukomalacia medlineplus "007232".
- Periventricular_leukomalacia meshId "D007969".
- Periventricular_leukomalacia thumbnail Gray734.png?width=300.
- Periventricular_leukomalacia wikiPageID "3117655".
- Periventricular_leukomalacia wikiPageRevisionID "600816079".
- Periventricular_leukomalacia diseasesdb "9868".
- Periventricular_leukomalacia emedicinesubj "ped".
- Periventricular_leukomalacia emedicinetopic "1773".
- Periventricular_leukomalacia hasPhotoCollection Periventricular_leukomalacia.
- Periventricular_leukomalacia icd "779.7".
- Periventricular_leukomalacia icd "P91.2".
- Periventricular_leukomalacia medlineplus "7232".
- Periventricular_leukomalacia meshid "D007969".
- Periventricular_leukomalacia name "Periventricular leukomalacia".
- Periventricular_leukomalacia wordnet_type synset-disease-noun-1.
- Periventricular_leukomalacia subject Category:Central_nervous_system_disorders.
- Periventricular_leukomalacia subject Category:Pediatrics.
- Periventricular_leukomalacia type Abstraction100002137.
- Periventricular_leukomalacia type Attribute100024264.
- Periventricular_leukomalacia type CentralNervousSystemDisorders.
- Periventricular_leukomalacia type Condition113920835.
- Periventricular_leukomalacia type Disease114070360.
- Periventricular_leukomalacia type Disorder114052403.
- Periventricular_leukomalacia type IllHealth114052046.
- Periventricular_leukomalacia type Illness114061805.
- Periventricular_leukomalacia type PathologicalState114051917.
- Periventricular_leukomalacia type PhysicalCondition114034177.
- Periventricular_leukomalacia type State100024720.
- Periventricular_leukomalacia type Disease.
- Periventricular_leukomalacia type AilmentCondition.
- Periventricular_leukomalacia type Situation.
- Periventricular_leukomalacia comment "Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.".
- Periventricular_leukomalacia label "Leucomalacia periventricolare".
- Periventricular_leukomalacia label "Periventricular leukomalacia".
- Periventricular_leukomalacia label "Periventrikuläre Leukomalazie".
- Periventricular_leukomalacia label "Перивентрикулярная лейкомаляция".
- Periventricular_leukomalacia sameAs Periventrikuläre_Leukomalazie.
- Periventricular_leukomalacia sameAs Leucomalacia_periventricolare.
- Periventricular_leukomalacia sameAs m.08skxx.
- Periventricular_leukomalacia sameAs Q469490.
- Periventricular_leukomalacia sameAs Q469490.
- Periventricular_leukomalacia sameAs Periventricular_leukomalacia.
- Periventricular_leukomalacia wasDerivedFrom Periventricular_leukomalacia?oldid=600816079.
- Periventricular_leukomalacia depiction Gray734.png.
- Periventricular_leukomalacia isPrimaryTopicOf Periventricular_leukomalacia.
- Periventricular_leukomalacia name "Periventricular leukomalacia".