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- Polly_and_Molly abstract "Polly and Molly (Born 1997), two ewes, were the first mammals to have been successfully cloned from an adult somatic cell and to be transgenic animals at the same time. This is not to be confused with Dolly the Sheep which was the first animal to be successfully cloned from an adult somatic cell where there was no genetic modification carried out on the adult donor nucleus. Polly and Molly, like Dolly the Sheep, were cloned at the Roslin Institute in Edinburgh, Scotland.The creation of Polly and Molly built on the somatic nuclear transfer experiments that led to the cloning of Dolly the Sheep. The crucial difference was that in creating Polly and Molly, scientists used cells into which a new gene had been inserted. The gene chosen was a therapeutic protein to demonstrate the potential of such recombinant DNA technology combined with animal cloning. This could produce pharmacological and therapeutic proteins to hopefully treat human diseases. The protein in question was the human blood clotting factor IX. Another difference from Dolly the Sheep was the source cell type of the nucleus that was transferred. In the case of Dolly the Sheep, the nucleus that was transferred came from mammary gland cells from a 6-year-old ewe; in the case of Polly and Molly, fibroblast cells were used.".
- Polly_and_Molly wikiPageID "1857574".
- Polly_and_Molly wikiPageRevisionID "559542848".
- Polly_and_Molly hasPhotoCollection Polly_and_Molly.
- Polly_and_Molly subject Category:1997_animal_births.
- Polly_and_Molly subject Category:Biotechnology.
- Polly_and_Molly subject Category:Cell_biology.
- Polly_and_Molly subject Category:Cloned_sheep.
- Polly_and_Molly subject Category:Developmental_biology.
- Polly_and_Molly subject Category:Genetics.
- Polly_and_Molly subject Category:Stem_cells.
- Polly_and_Molly comment "Polly and Molly (Born 1997), two ewes, were the first mammals to have been successfully cloned from an adult somatic cell and to be transgenic animals at the same time. This is not to be confused with Dolly the Sheep which was the first animal to be successfully cloned from an adult somatic cell where there was no genetic modification carried out on the adult donor nucleus.".
- Polly_and_Molly label "Oveja Polly".
- Polly_and_Molly label "Polly and Molly".
- Polly_and_Molly label "Полли и Молли".
- Polly_and_Molly label "بولي ومولي".
- Polly_and_Molly sameAs Oveja_Polly.
- Polly_and_Molly sameAs m.061jk7.
- Polly_and_Molly sameAs Q4370317.
- Polly_and_Molly sameAs Q4370317.
- Polly_and_Molly wasDerivedFrom Polly_and_Molly?oldid=559542848.
- Polly_and_Molly isPrimaryTopicOf Polly_and_Molly.