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- Protein_ligand abstract "In biochemistry, a protein ligand is an atom, a molecule or an ion which can bind to a specific site (the binding site) on a protein. Alternative names used to mean a protein ligand are affinity reagents or protein binders. To date, antibodies are the most widely used protein ligands in life-science investigations, however, other molecules such as protein scaffolds, nucleic acids, peptides are also being used.Main methods to study protein–ligand interactions are principal hydrodynamic and calorimetric techniques, and principal spectroscopic and structural methods such asFourier transform spectroscopyRaman spectroscopyFluorescence spectroscopyCircular dichroismNuclear magnetic resonanceMass spectrometryAtomic force microscopeParamagnetic probesDual Polarisation InterferometryOther techniques include:fluorescence intensity,bimolecular fluorescence complementation,FRET (fluorescent resonance energy transfer) / FRET quenchingsurface plasmon resonance,Bio-Layer Interferometry,Coimmunopreciptationindirect ELIS,equilibrium dialysis,gel electrophoresis,far western blot,fluorescence polarization anisotropy,electron paramagnetic resonance,Microscale ThermophoresisThe dramatically increased computing power of supercomputers and personal computers has made it possible to study protein–ligand interactions also by means of computational chemistry. For example, a worldwide grid of well over a million ordinary PCs was harnessed for cancer research in the project grid.org, which ended in April 2007. Grid.org has been succeeded by similar projects such as World Community Grid, Human Proteome Folding Project, Compute Against Cancer and Folding@Home.".
- Protein_ligand wikiPageID "1270870".
- Protein_ligand wikiPageRevisionID "552053943".
- Protein_ligand hasPhotoCollection Protein_ligand.
- Protein_ligand subject Category:Biomolecules.
- Protein_ligand subject Category:Chemical_bonding.
- Protein_ligand subject Category:Proteins.
- Protein_ligand type Abstraction100002137.
- Protein_ligand type Chemical114806838.
- Protein_ligand type Compound114818238.
- Protein_ligand type Macromolecule114944888.
- Protein_ligand type Material114580897.
- Protein_ligand type Matter100020827.
- Protein_ligand type Molecule114682133.
- Protein_ligand type OrganicCompound114727670.
- Protein_ligand type Part113809207.
- Protein_ligand type PhysicalEntity100001930.
- Protein_ligand type Protein114728724.
- Protein_ligand type Proteins.
- Protein_ligand type Relation100031921.
- Protein_ligand type Substance100019613.
- Protein_ligand type Thing100002452.
- Protein_ligand type Unit109465459.
- Protein_ligand comment "In biochemistry, a protein ligand is an atom, a molecule or an ion which can bind to a specific site (the binding site) on a protein. Alternative names used to mean a protein ligand are affinity reagents or protein binders.".
- Protein_ligand label "Protein ligand".
- Protein_ligand sameAs m.04nytz.
- Protein_ligand sameAs Q7251485.
- Protein_ligand sameAs Q7251485.
- Protein_ligand sameAs Protein_ligand.
- Protein_ligand wasDerivedFrom Protein_ligand?oldid=552053943.
- Protein_ligand isPrimaryTopicOf Protein_ligand.