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- Pyroglutamic_acid abstract "Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue.Pyroglutamic acid is also known as pidolic acid, exists as two distinct enantiomers:(2R) or D which happens to be (+) or l (2S) or L which happens to be (–) or d↑".
- Pyroglutamic_acid thumbnail (S)-Pyroglutamic_acid_Structural_Formulae.png?width=300.
- Pyroglutamic_acid wikiPageID "953465".
- Pyroglutamic_acid wikiPageRevisionID "559017422".
- Pyroglutamic_acid hasPhotoCollection Pyroglutamic_acid.
- Pyroglutamic_acid imagefile "-Pyroglutamic acid Structural Formulae.png".
- Pyroglutamic_acid imagename "Stereo structural formula of -pyroglutamic acid".
- Pyroglutamic_acid othernames "5".
- Pyroglutamic_acid othernames "Pidolic acid".
- Pyroglutamic_acid pin "5".
- Pyroglutamic_acid systematicname "5".
- Pyroglutamic_acid verifiedfields "changed".
- Pyroglutamic_acid verifiedrevid "464377606".
- Pyroglutamic_acid watchedfields "changed".
- Pyroglutamic_acid subject Category:Amino_acids.
- Pyroglutamic_acid subject Category:Pyrrolidones.
- Pyroglutamic_acid type Abstraction100002137.
- Pyroglutamic_acid type AminoAcid114601829.
- Pyroglutamic_acid type AminoAcids.
- Pyroglutamic_acid type Chemical114806838.
- Pyroglutamic_acid type Compound114818238.
- Pyroglutamic_acid type Material114580897.
- Pyroglutamic_acid type Matter100020827.
- Pyroglutamic_acid type OrganicCompound114727670.
- Pyroglutamic_acid type Part113809207.
- Pyroglutamic_acid type PhysicalEntity100001930.
- Pyroglutamic_acid type Relation100031921.
- Pyroglutamic_acid type Substance100019613.
- Pyroglutamic_acid type ChemicalCompound.
- Pyroglutamic_acid type ChemicalSubstance.
- Pyroglutamic_acid type ChemicalSubstanceType.
- Pyroglutamic_acid type ChemicalObject.
- Pyroglutamic_acid type Thing.
- Pyroglutamic_acid comment "Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate.".
- Pyroglutamic_acid label "Acide pyroglutamique".
- Pyroglutamic_acid label "Acido pidolico".
- Pyroglutamic_acid label "Pyroglutamic acid".
- Pyroglutamic_acid label "Pyroglutaminsäure".
- Pyroglutamic_acid label "Ácido piroglutámico".
- Pyroglutamic_acid label "ピログルタミン酸".
- Pyroglutamic_acid sameAs Pyroglutaminsäure.
- Pyroglutamic_acid sameAs Ácido_piroglutámico.
- Pyroglutamic_acid sameAs Acide_pyroglutamique.
- Pyroglutamic_acid sameAs Acido_pidolico.
- Pyroglutamic_acid sameAs ピログルタミン酸.
- Pyroglutamic_acid sameAs m.02kc8nn.
- Pyroglutamic_acid sameAs Q421383.
- Pyroglutamic_acid sameAs Q421383.
- Pyroglutamic_acid sameAs DB03088.
- Pyroglutamic_acid sameAs Pyroglutamic_acid.
- Pyroglutamic_acid wasDerivedFrom Pyroglutamic_acid?oldid=559017422.
- Pyroglutamic_acid depiction (S)-Pyroglutamic_acid_Structural_Formulae.png.
- Pyroglutamic_acid isPrimaryTopicOf Pyroglutamic_acid.