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- RVD-Hpα abstract "RVD-Hpα is an endogenous neuropeptide found in human and mammalian brain, which was originally proposed to act as a selective agonist for the CB1 cannabinoid receptor. It is a 12-amino acid polypeptide having the amino acid sequence Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His and is an N-terminal extended form of hemopressin, a 9-AA polypeptide derived from the α1 subunit of hemoglobin which has previously been shown to act as a CB1 inverse agonist. All three polypeptides have been isolated from various mammalian species, with RVD-Hpα being one of the more abundant neuropeptides expressed in mouse brain, and these neuropeptides represent a new avenue for cannabinoid research distinct from the previously known endogenous lipid-derived cannabinoid agonists such as anandamide. Recently it was shown that RVD-Hpα (also called Pepcan-12) is an potent negative allosteric modulator at CB1 receptors, together with other newly described N-terminally extended peptides (pepcans)".
- RVD-Hpα wikiPageID "26647818".
- RVD-Hpα wikiPageRevisionID "599397970".
- RVD-Hpα arm "p".
- RVD-Hpα band "13.3".
- RVD-Hpα caption "A polypeptide fragment derived from residues 92-104 in the human sequence".
- RVD-Hpα chromosome "16".
- RVD-Hpα entrezgene "3039".
- RVD-Hpα hgncid "4823".
- RVD-Hpα name "RVD-Hpα fragment of hemoglobin, alpha 1".
- RVD-Hpα omim "141800".
- RVD-Hpα refseq "NM_000558".
- RVD-Hpα symbol Hemoglobin,_alpha_1.
- RVD-Hpα uniprot "P69905".
- RVD-Hpα subject Category:Endocannabinoids.
- RVD-Hpα subject Category:Neuropeptides.
- RVD-Hpα type Biomolecule.
- RVD-Hpα type Protein.
- RVD-Hpα type BiologicalObject.
- RVD-Hpα comment "RVD-Hpα is an endogenous neuropeptide found in human and mammalian brain, which was originally proposed to act as a selective agonist for the CB1 cannabinoid receptor. It is a 12-amino acid polypeptide having the amino acid sequence Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His and is an N-terminal extended form of hemopressin, a 9-AA polypeptide derived from the α1 subunit of hemoglobin which has previously been shown to act as a CB1 inverse agonist.".
- RVD-Hpα label "RVD-Hpα".
- RVD-Hpα sameAs RVD-Hp%CE%B1.
- RVD-Hpα sameAs Q7278003.
- RVD-Hpα sameAs Q7278003.
- RVD-Hpα wasDerivedFrom RVD-Hpα?oldid=599397970.