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Raloxifene abstract "Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women. In 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk. A major adverse effect of tamoxifen is uterine cancer; raloxifene caused fewer cases of uterine cancer. Tamoxifen increased the risk of cataracts, but raloxifene did not. Both groups had more blood clots in veins and the lungs, but that side effect was more common with tamoxifen than raloxifene. On September 14, 2007, the U.S. Food and Drug Administration announced approval of raloxifene for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.An editorial in Lancet Oncology criticized the way that information about the drug was released.".
Raloxifene atcPrefix "G03".
Raloxifene atcSuffix "XC01".
Raloxifene bioavailability "2.0".
Raloxifene casNumber "84449-90-1".
Raloxifene chEBI "8772".
Raloxifene drugbank "DB00481".
Raloxifene fdaUniiCode "YX9162EO3I".
Raloxifene iupacName "[6-hydroxy-2-(4-hydroxyphenyl)- benzothiophen-3-yl]- [4-[2-(1-piperidyl)ethoxy]phenyl] -methanone".
Raloxifene pubchem "5035".
Raloxifene thumbnail Raloxifene_Chemical_Structure_V.1.svg?width=300.
Raloxifene wikiPageExternalLink evista-pi.pdf.
Raloxifene wikiPageExternalLink Index.html.
Raloxifene wikiPageExternalLink position_details.php?poid=5.
Raloxifene wikiPageID "1845623".
Raloxifene wikiPageRevisionID "602339014".
Raloxifene atcPrefix "G03".
Raloxifene atcSuffix "XC01".
Raloxifene bioavailability "2.0".
Raloxifene c "28".
Raloxifene casNumber "84449".
Raloxifene chebi "8772".
Raloxifene chembl "81".
Raloxifene chemspiderid "4859".
Raloxifene drugbank "DB00481".
Raloxifene eliminationHalfLife "99720.0".
Raloxifene excretion "Fecal".
Raloxifene h "27".
Raloxifene hasPhotoCollection Raloxifene.
Raloxifene inchi "1".
Raloxifene inchikey "GZUITABIAKMVPG-UHFFFAOYAG".
Raloxifene iupacName "[6-hydroxy-2-- benzothiophen-3-yl]- [4-[2-ethoxy]phenyl] -methanone".
Raloxifene iupharLigand "2820".
Raloxifene legalStatus "Rx-only".
Raloxifene licenceEu "Evista".
Raloxifene licenceUs "Evista".
Raloxifene medlineplus "a698007".
Raloxifene metabolism Glucuronidation.
Raloxifene metabolism Human_gastrointestinal_tract.
Raloxifene metabolism "CYP system not involved".
Raloxifene molecularWeight "473.584".
Raloxifene n "1".
Raloxifene o "4".
Raloxifene pdbLigand "RAL".
Raloxifene pregnancyAu "X".
Raloxifene pregnancyUs "X".
Raloxifene proteinBound "95.0".
Raloxifene pubchem "5035".
Raloxifene routesOfAdministration "Oral".
Raloxifene s "1".
Raloxifene smiles "O=Cc5ccccc5".
Raloxifene stdinchi "1".
Raloxifene stdinchikey "GZUITABIAKMVPG-UHFFFAOYSA-N".
Raloxifene tradename "Evista".
Raloxifene unii "YX9162EO3I".
Raloxifene verifiedrevid "464379874".
Raloxifene subject Category:Aromatic_ketones.
Raloxifene subject Category:Benzothiophenes.
Raloxifene subject Category:Eli_Lilly_and_Company.
Raloxifene subject Category:Phenol_ethers.
Raloxifene subject Category:Phenols.
Raloxifene subject Category:Piperidines.
Raloxifene subject Category:Selective_estrogen_receptor_modulators.
Raloxifene type Abstraction100002137.
Raloxifene type AromaticKetones.
Raloxifene type Chemical114806838.
Raloxifene type Compound114818238.
Raloxifene type Element114840755.
Raloxifene type Ketone114926294.
Raloxifene type Material114580897.
Raloxifene type Matter100020827.
Raloxifene type OrganicCompound114727670.
Raloxifene type Part113809207.
Raloxifene type Phenol114989545.
Raloxifene type PhenolEthers.
Raloxifene type Phenols.
Raloxifene type PhysicalEntity100001930.
Raloxifene type Quintessence114847103.
Raloxifene type Relation100031921.
Raloxifene type Substance100019613.
Raloxifene type Drug.
Raloxifene type DrugProduct.
Raloxifene type FunctionalSubstance.
Raloxifene comment "Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women. In 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk.".
Raloxifene label "Raloksifen".
Raloxifene label "Raloxifen".
Raloxifene label "Raloxifene".
Raloxifene label "Raloxifene".
Raloxifene label "Raloxifeno".
Raloxifene label "Raloxifène".
Raloxifene sameAs Raloxifen.
Raloxifene sameAs Raloxifen.
Raloxifene sameAs Raloxifeno.
Raloxifene sameAs Raloxifène.
Raloxifene sameAs Raloxifene.
Raloxifene sameAs Raloksifen.
Raloxifene sameAs m.060jym.
Raloxifene sameAs Q425223.
Raloxifene sameAs Q425223.
Raloxifene sameAs Raloxifene.