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- Ribose-phosphate_diphosphokinase abstract "Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase or ribose-phosphate pyrophosphokinase) is an enzyme that converts ribose 5-phosphate into phosphoribosyl pyrophosphate (PRPP). It is classified under EC 2.7.6.1.The enzyme is involved in the synthesis of nucleotides (purines and pyrimidines), cofactors NAD and NADP, and amino acids histidine and tryptophan, linking these biosynthetic processes to the pentose phosphate pathway, from which the substrate ribose 5-phosphate is derived. Ribose 5-phosphate is produced by the HMP Shunt Pathway from Glucose-6-Phosphate. The product phosphoribosyl pyrophosphate acts as an essential component of the purine salvage pathway and the de novo synthesis of purines. Dysfunction of the enzyme would thereby undermine purine metabolism. Ribose-phosphate pyrophosphokinase exists in bacteria, plants, and animals, and there are three isoforms of human ribose-phosphate pyrophosphokinase. In humans, the genes encoding the enzyme are located on the X chromosome.".
- Ribose-phosphate_diphosphokinase ecNumber "2.4.2.17".
- Ribose-phosphate_diphosphokinase thumbnail Phosphoribosyl_pyrophosphate_synthetase_equation.png?width=300.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink NBK1876.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink NBK57098.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink br.fcgi?book=gene&part=arts.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink br.fcgi?book=gene&part=prs.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink 311860,611566,311070,311850,311070,311850.
- Ribose-phosphate_diphosphokinase wikiPageExternalLink P60891.
- Ribose-phosphate_diphosphokinase wikiPageID "11403513".
- Ribose-phosphate_diphosphokinase wikiPageRevisionID "603159695".
- Ribose-phosphate_diphosphokinase arm "p".
- Ribose-phosphate_diphosphokinase arm "q".
- Ribose-phosphate_diphosphokinase band "21".
- Ribose-phosphate_diphosphokinase band "ter".
- Ribose-phosphate_diphosphokinase casNumber "9031".
- Ribose-phosphate_diphosphokinase chromosome "X".
- Ribose-phosphate_diphosphokinase ecNumber "2.4".
- Ribose-phosphate_diphosphokinase ecnumber "2.4".
- Ribose-phosphate_diphosphokinase entrezgene "5631".
- Ribose-phosphate_diphosphokinase entrezgene "5634".
- Ribose-phosphate_diphosphokinase goCode "3879".
- Ribose-phosphate_diphosphokinase hasPhotoCollection Ribose-phosphate_diphosphokinase.
- Ribose-phosphate_diphosphokinase hgncid "9462".
- Ribose-phosphate_diphosphokinase hgncid "9465".
- Ribose-phosphate_diphosphokinase iubmbEcNumber "2".
- Ribose-phosphate_diphosphokinase locussupplementarydata "-q21".
- Ribose-phosphate_diphosphokinase locussupplementarydata "-q27".
- Ribose-phosphate_diphosphokinase name "Ribose-phosphate diphosphokinase".
- Ribose-phosphate_diphosphokinase name "phosphoribosyl pyrophosphate synthetase 1".
- Ribose-phosphate_diphosphokinase name "phosphoribosyl pyrophosphate synthetase 2".
- Ribose-phosphate_diphosphokinase omim "311850".
- Ribose-phosphate_diphosphokinase omim "311860".
- Ribose-phosphate_diphosphokinase refseq "NM_002764".
- Ribose-phosphate_diphosphokinase refseq "NM_002765".
- Ribose-phosphate_diphosphokinase symbol "PRPS1".
- Ribose-phosphate_diphosphokinase symbol "PRPS2".
- Ribose-phosphate_diphosphokinase uniprot "P11908".
- Ribose-phosphate_diphosphokinase uniprot "P60891".
- Ribose-phosphate_diphosphokinase subject Category:EC_2.4.2.
- Ribose-phosphate_diphosphokinase type Biomolecule.
- Ribose-phosphate_diphosphokinase type Enzyme.
- Ribose-phosphate_diphosphokinase type ProteinMolecule.
- Ribose-phosphate_diphosphokinase type BiologicalObject.
- Ribose-phosphate_diphosphokinase comment "Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase or ribose-phosphate pyrophosphokinase) is an enzyme that converts ribose 5-phosphate into phosphoribosyl pyrophosphate (PRPP).".
- Ribose-phosphate_diphosphokinase label "Ribosa-fosfato difosfoquinasa".
- Ribose-phosphate_diphosphokinase label "Ribose-phosphate diphosphokinase".
- Ribose-phosphate_diphosphokinase label "Ribosephosphat-Diphosphokinase".
- Ribose-phosphate_diphosphokinase label "リボース-リン酸ジホスホキナーゼ".
- Ribose-phosphate_diphosphokinase sameAs Ribosephosphat-Diphosphokinase.
- Ribose-phosphate_diphosphokinase sameAs Ribosa-fosfato_difosfoquinasa.
- Ribose-phosphate_diphosphokinase sameAs リボース-リン酸ジホスホキナーゼ.
- Ribose-phosphate_diphosphokinase sameAs m.02rbcct.
- Ribose-phosphate_diphosphokinase sameAs Q414497.
- Ribose-phosphate_diphosphokinase sameAs Q414497.
- Ribose-phosphate_diphosphokinase wasDerivedFrom Ribose-phosphate_diphosphokinase?oldid=603159695.
- Ribose-phosphate_diphosphokinase depiction Phosphoribosyl_pyrophosphate_synthetase_equation.png.
- Ribose-phosphate_diphosphokinase isPrimaryTopicOf Ribose-phosphate_diphosphokinase.
- Ribose-phosphate_diphosphokinase name "Ribose-phosphate diphosphokinase".