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- Robalzotan abstract "Robalzotan (NAD-299, AZD-7371) is a selective antagonist at the 5-HT1A receptor. It was shown to completely reverse the autoreceptor-mediated inhibition of serotonin release induced by the administration of selective serotonin reuptake inhibitors like citalopram in rodent studies. It was subsequently investigated by AstraZeneca as a potential antidepressant but like many other 5-HT1A ligands was discontinued. Later on it was researched for other indications such as irritable bowel syndrome but was dropped once again.".
- Robalzotan atcPrefix "none".
- Robalzotan casNumber "169758-66-1".
- Robalzotan fdaUniiCode "I18M56OGME".
- Robalzotan iupacName "(3R)-3-[di(cyclobutyl)amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide".
- Robalzotan pubchem "3055171".
- Robalzotan thumbnail Robalzotan.png?width=300.
- Robalzotan wikiPageID "22570393".
- Robalzotan wikiPageRevisionID "592944461".
- Robalzotan atcPrefix "none".
- Robalzotan c "18".
- Robalzotan casNumber "169758".
- Robalzotan chemspiderid "2316732".
- Robalzotan f "1".
- Robalzotan h "23".
- Robalzotan hasPhotoCollection Robalzotan.
- Robalzotan inchi "1".
- Robalzotan inchikey "MQTUXRKNJYPMCG-CYBMUJFWBV".
- Robalzotan iupacName "-3".
- Robalzotan legalStatus "Uncontrolled".
- Robalzotan molecularWeight "318.174".
- Robalzotan n "2".
- Robalzotan o "2".
- Robalzotan pubchem "3055171".
- Robalzotan routesOfAdministration "Oral".
- Robalzotan smiles "C1CCN[C@@H]3CC4=CCN".
- Robalzotan stdinchi "1".
- Robalzotan stdinchikey "MQTUXRKNJYPMCG-CYBMUJFWSA-N".
- Robalzotan unii "I18M56OGME".
- Robalzotan verifiedrevid "448230811".
- Robalzotan subject Category:Amines.
- Robalzotan subject Category:Carboxamides.
- Robalzotan subject Category:Chromenes.
- Robalzotan subject Category:Organofluorides.
- Robalzotan type Abstraction100002137.
- Robalzotan type AliphaticCompound114601294.
- Robalzotan type Amine114739004.
- Robalzotan type Amines.
- Robalzotan type Chemical114806838.
- Robalzotan type Compound114818238.
- Robalzotan type Material114580897.
- Robalzotan type Matter100020827.
- Robalzotan type MethaneSeries114951377.
- Robalzotan type OrganicCompound114727670.
- Robalzotan type Part113809207.
- Robalzotan type PhysicalEntity100001930.
- Robalzotan type Relation100031921.
- Robalzotan type Substance100019613.
- Robalzotan type Drug.
- Robalzotan type DrugProduct.
- Robalzotan type FunctionalSubstance.
- Robalzotan comment "Robalzotan (NAD-299, AZD-7371) is a selective antagonist at the 5-HT1A receptor. It was shown to completely reverse the autoreceptor-mediated inhibition of serotonin release induced by the administration of selective serotonin reuptake inhibitors like citalopram in rodent studies. It was subsequently investigated by AstraZeneca as a potential antidepressant but like many other 5-HT1A ligands was discontinued.".
- Robalzotan label "Robalzotan".
- Robalzotan sameAs m.05zzp3q.
- Robalzotan sameAs Q7340703.
- Robalzotan sameAs Q7340703.
- Robalzotan sameAs Robalzotan.
- Robalzotan wasDerivedFrom Robalzotan?oldid=592944461.
- Robalzotan depiction Robalzotan.png.
- Robalzotan isPrimaryTopicOf Robalzotan.