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- Romidepsin abstract "Romidepsin (INN, trade name Istodax), codenamed FK228 and FR901228, is an anticancer agent undergoing clinical trials as a treatment for cutaneous T-cell lymphoma (CTCL), peripheral T-cell lymphoma, and a variety of other cancers. Romidepsin is a natural product obtained from the bacteria Chromobacterium violaceum, and works by blocking enzymes known as histone deacetylases and inducing apoptosis. It is sometimes referred to as depsipeptide, after the class of molecules to which it belongs.Romidepsin is branded and owned by Gloucester Pharmaceuticals, now a part of Celgene. On November 5, 2009, it was approved by the U.S. Food and Drug Administration for the treatment of CTCL, after five years in the agency's fast track development program.".
- Romidepsin atcPrefix "none".
- Romidepsin casNumber "128517-07-7".
- Romidepsin chEBI "61080".
- Romidepsin fdaUniiCode "CX3T89XQBK".
- Romidepsin iupacName "(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone".
- Romidepsin pubchem "5352062".
- Romidepsin thumbnail Romidepsin_structure_(2).svg?width=300.
- Romidepsin wikiPageExternalLink results?term=romidepsin.
- Romidepsin wikiPageID "24314125".
- Romidepsin wikiPageRevisionID "592953384".
- Romidepsin alt "Skeletal formula of -7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone".
- Romidepsin atcPrefix "none".
- Romidepsin bioavailability "Not applicable".
- Romidepsin c "24".
- Romidepsin casNumber "128517".
- Romidepsin chebi "61080".
- Romidepsin chembl "1213490".
- Romidepsin colwidth "30".
- Romidepsin eliminationHalfLife "10800.0".
- Romidepsin h "36".
- Romidepsin hasPhotoCollection Romidepsin.
- Romidepsin image "Romidepsin ball and spoke.png".
- Romidepsin iupacName "-7".
- Romidepsin legalUs "Rx-only".
- Romidepsin licenceUs "Romidepsin".
- Romidepsin medlineplus "a610005".
- Romidepsin metabolism "Hepatic".
- Romidepsin molecularWeight "540.695".
- Romidepsin n "4".
- Romidepsin o "6".
- Romidepsin pregnancyUs "D".
- Romidepsin proteinBound "92".
- Romidepsin pubchem "5352062".
- Romidepsin routesOfAdministration Intravenous_therapy.
- Romidepsin s "2".
- Romidepsin synonyms "FK228; FR901228; Istodax".
- Romidepsin tradename "Istodax".
- Romidepsin unii "CX3T89XQBK".
- Romidepsin verifiedfields "changed".
- Romidepsin verifiedrevid "387635110".
- Romidepsin watchedfields "changed".
- Romidepsin width "200".
- Romidepsin subject Category:Antineoplastic_drugs.
- Romidepsin subject Category:Depsipeptides.
- Romidepsin subject Category:Histone_deacetylase_inhibitors.
- Romidepsin subject Category:Orphan_drugs.
- Romidepsin subject Category:Prodrugs.
- Romidepsin type Agent114778436.
- Romidepsin type Antineoplastic102722458.
- Romidepsin type AntineoplasticDrugs.
- Romidepsin type CausalAgent100007347.
- Romidepsin type CytotoxicDrug103157987.
- Romidepsin type Drug103247620.
- Romidepsin type HistoneDeacetylaseInhibitors.
- Romidepsin type Inhibitor114724436.
- Romidepsin type Matter100020827.
- Romidepsin type Medicine103740161.
- Romidepsin type OrphanDrugs.
- Romidepsin type PhysicalEntity100001930.
- Romidepsin type Substance100020090.
- Romidepsin type Drug.
- Romidepsin type DrugProduct.
- Romidepsin type FunctionalSubstance.
- Romidepsin comment "Romidepsin (INN, trade name Istodax), codenamed FK228 and FR901228, is an anticancer agent undergoing clinical trials as a treatment for cutaneous T-cell lymphoma (CTCL), peripheral T-cell lymphoma, and a variety of other cancers. Romidepsin is a natural product obtained from the bacteria Chromobacterium violaceum, and works by blocking enzymes known as histone deacetylases and inducing apoptosis.".
- Romidepsin label "Romidepsin".
- Romidepsin sameAs m.07s5_vc.
- Romidepsin sameAs Q7363205.
- Romidepsin sameAs Q7363205.
- Romidepsin sameAs Romidepsin.
- Romidepsin wasDerivedFrom Romidepsin?oldid=592953384.
- Romidepsin depiction Romidepsin_structure_(2).svg.
- Romidepsin isPrimaryTopicOf Romidepsin.