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- SB-334,867 abstract "SB-334,867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other physiological processes. Orexin antagonists have multiple potential clinical applications including the treatment of drug addiction, insomnia, obesity and diabetes.".
- SB-334,867 casNumber "249889-64-3".
- SB-334,867 iupacName "1-(2-methylbenzoxazol- 6-yl)- 3-[1,5]naphthyridin- 4-yl urea".
- SB-334,867 pubchem "6604926".
- SB-334,867 thumbnail SB334867_structure.png?width=300.
- SB-334,867 wikiPageID "22230687".
- SB-334,867 wikiPageRevisionID "598132526".
- SB-334,867 c "17".
- SB-334,867 casNumber "249889".
- SB-334,867 chembl "291536".
- SB-334,867 chemspiderid "5037182".
- SB-334,867 h "13".
- SB-334,867 hasPhotoCollection SB-334,867.
- SB-334,867 inchi "1".
- SB-334,867 inchikey "AKMNUCBQGHFICM-UHFFFAOYAZ".
- SB-334,867 iupacName "1".
- SB-334,867 iupharLigand "1703".
- SB-334,867 molecularWeight "319.317".
- SB-334,867 n "5".
- SB-334,867 o "2".
- SB-334,867 pubchem "6604926".
- SB-334,867 smiles "O=CNc3ccc4ncC".
- SB-334,867 stdinchi "1".
- SB-334,867 stdinchikey "AKMNUCBQGHFICM-UHFFFAOYSA-N".
- SB-334,867 verifiedfields "changed".
- SB-334,867 verifiedrevid "464385140".
- SB-334,867 width "240".
- SB-334,867 subject Category:Benzoxazoles.
- SB-334,867 subject Category:Naphthyridines.
- SB-334,867 subject Category:Orexin_antagonists.
- SB-334,867 subject Category:Sedatives.
- SB-334,867 subject Category:Ureas.
- SB-334,867 type Drug.
- SB-334,867 type DrugProduct.
- SB-334,867 type FunctionalSubstance.
- SB-334,867 comment "SB-334,867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other physiological processes.".
- SB-334,867 label "SB-334,867".
- SB-334,867 sameAs m.05q6jtj.
- SB-334,867 sameAs Q7388911.
- SB-334,867 sameAs Q7388911.
- SB-334,867 wasDerivedFrom SB-334,867?oldid=598132526.
- SB-334,867 depiction SB334867_structure.png.
- SB-334,867 isPrimaryTopicOf SB-334,867.