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- SCH-58261 abstract "SCH-58261 is a drug which acts as a potent and selective antagonist for the adenosine receptor A2A, with more than 50x selectivity for A2A over other adenosine receptors. It has been used to investigate the mechanism of action of caffeine, which is a mixed A1 / A2A antagonist, and has shown that the A2A receptor is primarily responsible for the stimulant effects of caffeine, but blockade of both A1 and A2A receptors is required to accurately replicate caffeine's effects in animals. SCH-58261 has also shown antidepressant and neuroprotective effects in a variety of animal models, and has been investigated as a possible treatment for Parkinson's disease.".
- SCH-58261 atcPrefix "none".
- SCH-58261 casNumber "160098-96-4".
- SCH-58261 iupacName "5-Amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine".
- SCH-58261 pubchem "176408".
- SCH-58261 thumbnail SCH-58261_structure.png?width=300.
- SCH-58261 wikiPageID "14466160".
- SCH-58261 wikiPageRevisionID "593008260".
- SCH-58261 atcPrefix "none".
- SCH-58261 c "18".
- SCH-58261 casNumber "160098".
- SCH-58261 chembl "17127".
- SCH-58261 chemspiderid "153647".
- SCH-58261 h "15".
- SCH-58261 hasPhotoCollection SCH-58261.
- SCH-58261 iupacName "5".
- SCH-58261 iupharLigand "403".
- SCH-58261 legalStatus "Uncontrolled".
- SCH-58261 molecularWeight "345.357".
- SCH-58261 n "7".
- SCH-58261 o "1".
- SCH-58261 pubchem "176408".
- SCH-58261 smiles "NC1=NC2=CC4[N]1=NC=N4".
- SCH-58261 stdinchi "1".
- SCH-58261 stdinchikey "UTLPKQYUXOEJIL-UHFFFAOYSA-N".
- SCH-58261 verifiedfields "changed".
- SCH-58261 verifiedrevid "477856283".
- SCH-58261 watchedfields "changed".
- SCH-58261 subject Category:Receptor_antagonists.
- SCH-58261 type Drug.
- SCH-58261 type FunctionalSubstance.
- SCH-58261 comment "SCH-58261 is a drug which acts as a potent and selective antagonist for the adenosine receptor A2A, with more than 50x selectivity for A2A over other adenosine receptors. It has been used to investigate the mechanism of action of caffeine, which is a mixed A1 / A2A antagonist, and has shown that the A2A receptor is primarily responsible for the stimulant effects of caffeine, but blockade of both A1 and A2A receptors is required to accurately replicate caffeine's effects in animals.".
- SCH-58261 label "SCH-58261".
- SCH-58261 sameAs m.0g54jmk.
- SCH-58261 sameAs Q7389140.
- SCH-58261 sameAs Q7389140.
- SCH-58261 wasDerivedFrom SCH-58261?oldid=593008260.
- SCH-58261 depiction SCH-58261_structure.png.
- SCH-58261 isPrimaryTopicOf SCH-58261.