Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SQ109> ?p ?o. }
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- SQ109 abstract "SQ109 is a drug undergoing development for treatment of tuberculosis.On October 16th, 2007, it was given the status of Orphan drug by the U.S. Food and Drug Administration (FDA) for use against drug-susceptible and drug-resistant TB bacteria.SQ109 completed three phase I studies in the U.S. and one Phase II efficacy studies in tuberculosis patients in Africa. SQ109 showed activity against both drug susceptible and Multi-drug-resistant tuberculosis bacteria, including Extensively drug-resistant tuberculosis strains. In preclinical studies SQ109 enhanced the activity of anti-tubercular drugs isoniazid and rifampin and reduced by >30% the time required to cure mice of experimental TB.SQ109 is being developed by OOO Infectex in Russia and by Sequella Inc internationally. In July 2012, Infectex received notification from the Russian Ministry of Health for approval to begin the pivotal clinical trial associated with a drug registration submission, and can proceed with the clinical development of SQ109 for treatment of tuberculosis in the Russian Federation.".
- SQ109 iupacName "N-Adamantan-2-yl-N'-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine".
- SQ109 thumbnail AntitubercularSQ109.svg?width=300.
- SQ109 wikiPageID "24237424".
- SQ109 wikiPageRevisionID "571470067".
- SQ109 hasPhotoCollection SQ109.
- SQ109 imagefile "AntitubercularSQ109.svg".
- SQ109 iupacname "N-Adamantan-2-yl-N'--ethane-1,2-diamine".
- SQ109 verifiedrevid "424997271".
- SQ109 subject Category:Adamantanes.
- SQ109 subject Category:Tuberculosis.
- SQ109 type ChemicalCompound.
- SQ109 type ChemicalSubstance.
- SQ109 type ChemicalSubstanceType.
- SQ109 type ChemicalObject.
- SQ109 type Thing.
- SQ109 comment "SQ109 is a drug undergoing development for treatment of tuberculosis.On October 16th, 2007, it was given the status of Orphan drug by the U.S. Food and Drug Administration (FDA) for use against drug-susceptible and drug-resistant TB bacteria.SQ109 completed three phase I studies in the U.S. and one Phase II efficacy studies in tuberculosis patients in Africa.".
- SQ109 label "SQ109".
- SQ109 label "SQ109".
- SQ109 sameAs m.07k6tj4.
- SQ109 sameAs Q7392720.
- SQ109 sameAs Q7392720.
- SQ109 wasDerivedFrom SQ109?oldid=571470067.
- SQ109 depiction AntitubercularSQ109.svg.
- SQ109 isPrimaryTopicOf SQ109.