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- Sarizotan abstract "Sarizotan (EMD-128,130) is a selective 5-HT1A receptor agonist and D2 receptor antagonist, which has antipsychotic effects, and has also shown efficacy in reducing dyskinesias resulting from long-term anti-Parkinsonian treatment with levodopa.In June 2006, the developer Merck KGaA announced that the development of sarizotan was discontinued, after two sarizotan Phase III studies (PADDY I, PADDY II) failed to meet the primary efficacy endpoint and neither the Phase II findings nor the results from preclinical studies could be confirmed. No statistically significant difference of the primary target variable between sarizotan and placebo could be demonstrated.".
- Sarizotan atcPrefix "none".
- Sarizotan casNumber "177975-08-5".
- Sarizotan fdaUniiCode "467LU0UCUW".
- Sarizotan iupacName "1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-([5-(4-fluorophenyl)pyridin-3-yl]methyl)methanamine".
- Sarizotan pubchem "6918388".
- Sarizotan thumbnail Sarizotan.png?width=300.
- Sarizotan wikiPageID "26637162".
- Sarizotan wikiPageRevisionID "545868486".
- Sarizotan atcPrefix "none".
- Sarizotan c "22".
- Sarizotan casNumber "177975".
- Sarizotan chemspiderid "2319847".
- Sarizotan f "1".
- Sarizotan h "21".
- Sarizotan hasPhotoCollection Sarizotan.
- Sarizotan iupacName "1".
- Sarizotan legalStatus "Discontinued".
- Sarizotan molecularWeight "348.413".
- Sarizotan n "2".
- Sarizotan o "1".
- Sarizotan pregnancyCategory "N/A".
- Sarizotan pubchem "6918388".
- Sarizotan routesOfAdministration "Oral".
- Sarizotan smiles "C1CC2=CC=CC=C2O[C@H]1CNCC3=CN=CCC4=CC=CF".
- Sarizotan unii "467".
- Sarizotan subject Category:Amines.
- Sarizotan subject Category:Chromanes.
- Sarizotan subject Category:Organofluorides.
- Sarizotan subject Category:Pyridines.
- Sarizotan type Abstraction100002137.
- Sarizotan type AliphaticCompound114601294.
- Sarizotan type Amine114739004.
- Sarizotan type Amines.
- Sarizotan type Base114618253.
- Sarizotan type Chemical114806838.
- Sarizotan type Compound114818238.
- Sarizotan type Material114580897.
- Sarizotan type Matter100020827.
- Sarizotan type MethaneSeries114951377.
- Sarizotan type OrganicCompound114727670.
- Sarizotan type Part113809207.
- Sarizotan type PhysicalEntity100001930.
- Sarizotan type Pyridine114692510.
- Sarizotan type Pyridines.
- Sarizotan type Relation100031921.
- Sarizotan type Substance100019613.
- Sarizotan type Drug.
- Sarizotan type FunctionalSubstance.
- Sarizotan comment "Sarizotan (EMD-128,130) is a selective 5-HT1A receptor agonist and D2 receptor antagonist, which has antipsychotic effects, and has also shown efficacy in reducing dyskinesias resulting from long-term anti-Parkinsonian treatment with levodopa.In June 2006, the developer Merck KGaA announced that the development of sarizotan was discontinued, after two sarizotan Phase III studies (PADDY I, PADDY II) failed to meet the primary efficacy endpoint and neither the Phase II findings nor the results from preclinical studies could be confirmed. ".
- Sarizotan label "Sarizotan".
- Sarizotan sameAs m.0bh9q3x.
- Sarizotan sameAs Q7424144.
- Sarizotan sameAs Q7424144.
- Sarizotan sameAs Sarizotan.
- Sarizotan wasDerivedFrom Sarizotan?oldid=545868486.
- Sarizotan depiction Sarizotan.png.
- Sarizotan isPrimaryTopicOf Sarizotan.