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- Scleroderma abstract "Scleroderma, also known as systemic sclerosis is a chronic systemic autoimmune disease, that primarily affects the skin (hence the suffix, "derma"), is characterised by sclerosis (hence the prefix, "sclero"), that is hardening of the skin.Limited scleroderma involves cutaneous manifestations that mainly affect the hands, arms and face. It was previously called CREST syndrome in reference to the following common manifestations: calcinosis (the deposition of calcium nodules in the skin),raynaud's phenomenon (exaggerated vasoconstriction in the hands, with fingers undergoing white-blue-red color transitions in the cold), esophageal dysfunction (leading to difficulty swallowing), sclerodactyly (skin thickening on the fingers), and telangiectasias (dilated capillaries on the face, hands and mucous membranes).Diffuse scleroderma is rapidly progressing and affects a large area of the skin and one or more internal organs, frequently the kidneys, oesophagus, heart and/or lungs. This form of scleroderma can be quite disabling. There are no treatments for scleroderma itself, but individual organ system complications are treated.The prognosis is generally good for limited cutaneous scleroderma persons who escape pulmonary complications, but is worse for those with the diffuse cutaneous disease, particularly in older age and for males. Death occurs most often from pulmonary, heart and kidney complications. In diffuse cutaneous disease, five-year survival is 70% and 10-year survival is 55%.Scleroderma is said to be of unknown aetiology, that is, it is unknown as to what exactly causes it. Although it is generally accepted that it is an autoimmune condition, that is a condition in which the body's immune system attacks healthy tissues, instead of the invaders and cancers it is meant to go after. Despite its unknown aetiology, strong associations between certain mutations in the HLA gene have been identified. Strong environment influences have also been implicated in the aetiology of scleroderma.".
- Scleroderma icd10 "L94.0-L94.1, M34".
- Scleroderma icd9 "701.0 710.1".
- Scleroderma medlineplus "000429".
- Scleroderma thumbnail MercMorphea.JPG?width=300.
- Scleroderma wikiPageID "21587184".
- Scleroderma wikiPageRevisionID "606400194".
- Scleroderma 250pxCaption Morphea.
- Scleroderma hasPhotoCollection Scleroderma.
- Scleroderma icd "701".
- Scleroderma icd "L94.0-L94.1, M34".
- Scleroderma medlineplus "429".
- Scleroderma name "Scleroderma".
- Scleroderma wordnet_type synset-disease-noun-1.
- Scleroderma subject Category:Autoimmune_diseases.
- Scleroderma subject Category:Mucinoses.
- Scleroderma subject Category:Systemic_connective_tissue_disorders.
- Scleroderma type Disease.
- Scleroderma type AilmentCondition.
- Scleroderma type Situation.
- Scleroderma comment "Scleroderma, also known as systemic sclerosis is a chronic systemic autoimmune disease, that primarily affects the skin (hence the suffix, "derma"), is characterised by sclerosis (hence the prefix, "sclero"), that is hardening of the skin.Limited scleroderma involves cutaneous manifestations that mainly affect the hands, arms and face.".
- Scleroderma label "Esclerodermia".
- Scleroderma label "Esclerodermia".
- Scleroderma label "Scleroderma".
- Scleroderma label "Sclerodermia".
- Scleroderma label "Sclerodermie".
- Scleroderma label "Sclérodermie".
- Scleroderma label "Sklerodermie".
- Scleroderma label "Twardzina".
- Scleroderma label "Склеродерма".
- Scleroderma label "تصلب الجلد".
- Scleroderma label "強皮症".
- Scleroderma label "硬皮病".
- Scleroderma sameAs Sklerodermie.
- Scleroderma sameAs Σκληρόδερμα.
- Scleroderma sameAs Esclerodermia.
- Scleroderma sameAs Sclérodermie.
- Scleroderma sameAs Skleroderma.
- Scleroderma sameAs Sclerodermia.
- Scleroderma sameAs 強皮症.
- Scleroderma sameAs Sclerodermie.
- Scleroderma sameAs Twardzina.
- Scleroderma sameAs Esclerodermia.
- Scleroderma sameAs m.05m_zv2.
- Scleroderma sameAs Q958797.
- Scleroderma sameAs Q958797.
- Scleroderma sameAs C0036421.
- Scleroderma wasDerivedFrom Scleroderma?oldid=606400194.
- Scleroderma depiction MercMorphea.JPG.
- Scleroderma isPrimaryTopicOf Scleroderma.
- Scleroderma name "Scleroderma".