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- Sea_anemone_neurotoxin abstract "Sea anemone neurotoxin is the name given to neurotoxins produced by sea anemones with related structure and function.A number of proteins belong to this family, including calitoxin and anthopleurin. The neurotoxins bind specifically to the sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of mammalian cardiac muscle contraction. Calitoxin 1 has been found in neuromuscular preparations of crustaceans, where it increases transmitter release, causing firing of the axons. Three disulfide bonds are present in this protein.This family also includes the antihypertensive and antiviral proteins BDS-I (P11494) and BDS-II (P59084) expressed by Anemonia sulcata. BDS-I is organised into a triple-stranded antiparallel beta-sheet, with an additional small antiparallel beta-sheet at the N-terminus. Both peptides are known to specifically block the Kv3.4 potassium channel, and thus bring about a decrease in blood pressure. Moreover, they inhibit the cytopathic effects of mouse hepatitis virus strain MHV-A59 on mouse liver cells, by an unknown mechanism.".
- Sea_anemone_neurotoxin symbol "BDS_I_II".
- Sea_anemone_neurotoxin symbol "Toxin_4".
- Sea_anemone_neurotoxin thumbnail PDB_1atx_EBI.jpg?width=300.
- Sea_anemone_neurotoxin wikiPageID "14846478".
- Sea_anemone_neurotoxin wikiPageRevisionID "603076871".
- Sea_anemone_neurotoxin caption "Structure of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata.".
- Sea_anemone_neurotoxin caption "Structure of the neurotoxin ATX Ia from Anemonia sulcata.".
- Sea_anemone_neurotoxin hasPhotoCollection Sea_anemone_neurotoxin.
- Sea_anemone_neurotoxin interpro "IPR000693".
- Sea_anemone_neurotoxin interpro "IPR012414".
- Sea_anemone_neurotoxin name "Anemone neurotoxin".
- Sea_anemone_neurotoxin name "Antihypertensive protein BDS-I/II".
- Sea_anemone_neurotoxin opmFamily "56".
- Sea_anemone_neurotoxin opmProtein "1".
- Sea_anemone_neurotoxin pfam "PF00706".
- Sea_anemone_neurotoxin pfam "PF07936".
- Sea_anemone_neurotoxin pfamClan "CL0075".
- Sea_anemone_neurotoxin scop "1".
- Sea_anemone_neurotoxin scop "2".
- Sea_anemone_neurotoxin symbol "BDS_I_II".
- Sea_anemone_neurotoxin symbol "Toxin_4".
- Sea_anemone_neurotoxin subject Category:Invertebrate_toxins.
- Sea_anemone_neurotoxin subject Category:Neurotoxins.
- Sea_anemone_neurotoxin subject Category:Peripheral_membrane_proteins.
- Sea_anemone_neurotoxin subject Category:Protein_domains.
- Sea_anemone_neurotoxin type Abstraction100002137.
- Sea_anemone_neurotoxin type Attribute100024264.
- Sea_anemone_neurotoxin type Chemical114806838.
- Sea_anemone_neurotoxin type Compound114818238.
- Sea_anemone_neurotoxin type Environment113934596.
- Sea_anemone_neurotoxin type Macromolecule114944888.
- Sea_anemone_neurotoxin type Material114580897.
- Sea_anemone_neurotoxin type Matter100020827.
- Sea_anemone_neurotoxin type Molecule114682133.
- Sea_anemone_neurotoxin type OrganicCompound114727670.
- Sea_anemone_neurotoxin type Part113809207.
- Sea_anemone_neurotoxin type PeripheralMembraneProteins.
- Sea_anemone_neurotoxin type PhysicalEntity100001930.
- Sea_anemone_neurotoxin type Protein114728724.
- Sea_anemone_neurotoxin type ProteinDomains.
- Sea_anemone_neurotoxin type Relation100031921.
- Sea_anemone_neurotoxin type Situation113927383.
- Sea_anemone_neurotoxin type Sphere114514039.
- Sea_anemone_neurotoxin type State100024720.
- Sea_anemone_neurotoxin type Substance100019613.
- Sea_anemone_neurotoxin type Thing100002452.
- Sea_anemone_neurotoxin type Unit109465459.
- Sea_anemone_neurotoxin type Biomolecule.
- Sea_anemone_neurotoxin type Protein.
- Sea_anemone_neurotoxin type BiologicalObject.
- Sea_anemone_neurotoxin comment "Sea anemone neurotoxin is the name given to neurotoxins produced by sea anemones with related structure and function.A number of proteins belong to this family, including calitoxin and anthopleurin. The neurotoxins bind specifically to the sodium channel, thereby delaying its inactivation during signal transduction, resulting in strong stimulation of mammalian cardiac muscle contraction.".
- Sea_anemone_neurotoxin label "Sea anemone neurotoxin".
- Sea_anemone_neurotoxin sameAs m.03gzyf2.
- Sea_anemone_neurotoxin sameAs Q7440052.
- Sea_anemone_neurotoxin sameAs Q7440052.
- Sea_anemone_neurotoxin sameAs Sea_anemone_neurotoxin.
- Sea_anemone_neurotoxin wasDerivedFrom Sea_anemone_neurotoxin?oldid=603076871.
- Sea_anemone_neurotoxin depiction PDB_1atx_EBI.jpg.
- Sea_anemone_neurotoxin isPrimaryTopicOf Sea_anemone_neurotoxin.
