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- Sonepiprazole abstract "Sonepiprazole (U-101,387, PNU-101,387-G) is a drug of the phenylpiperazine class which acts as a highly selective D4 receptor antagonist. In animals, unlike D2 receptor antagonists like haloperidol, sonepiprazole does not block the behavioral effects of amphetamine or apomorphine, does not alter spontaneous locomotor activity on its own, and lacks extrapyramidal and neuroendocrine effects. However, it does reverse the prepulse inhibition deficits induced by apomorphine, and has also been shown to enhance cortical activity and inhibit stress-induced cognitive impairment. As a result, it was investigated as an antipsychotic for the treatment of schizophrenia in a placebo-controlled clinical trial, but in contrast to its comparator olanzapine no benefits were found and it was not researched further for this indication.".
- Sonepiprazole atcPrefix "none".
- Sonepiprazole casNumber "170858-34-1".
- Sonepiprazole fdaUniiCode "O609V24217".
- Sonepiprazole iupacName "4-(4-{2-[(1S)-3,4-dihydro-1H-isochromen-1-yl]ethyl}piperazin-1-yl)benzenesulfonamide".
- Sonepiprazole pubchem "133079".
- Sonepiprazole thumbnail Sonepiprazole.png?width=300.
- Sonepiprazole wikiPageID "27132570".
- Sonepiprazole wikiPageRevisionID "593073610".
- Sonepiprazole atcPrefix "none".
- Sonepiprazole c "21".
- Sonepiprazole casNumber "170858".
- Sonepiprazole chemspiderid "117441".
- Sonepiprazole h "27".
- Sonepiprazole hasPhotoCollection Sonepiprazole.
- Sonepiprazole iupacName "4".
- Sonepiprazole legalStatus "Uncontrolled".
- Sonepiprazole molecularWeight "401.52".
- Sonepiprazole n "3".
- Sonepiprazole o "3".
- Sonepiprazole pubchem "133079".
- Sonepiprazole routesOfAdministration Mouth.
- Sonepiprazole s "1".
- Sonepiprazole smiles "O=Sc1cccN2CCNCC[C@@H]4OCCc3ccccc34".
- Sonepiprazole unii "O609V24217".
- Sonepiprazole subject Category:Isochromenes.
- Sonepiprazole subject Category:Piperazines.
- Sonepiprazole subject Category:Sulfonamides.
- Sonepiprazole type Agent114778436.
- Sonepiprazole type Antibacterial102716205.
- Sonepiprazole type CausalAgent100007347.
- Sonepiprazole type Drug103247620.
- Sonepiprazole type Matter100020827.
- Sonepiprazole type Medicine103740161.
- Sonepiprazole type PhysicalEntity100001930.
- Sonepiprazole type Piperazine103946814.
- Sonepiprazole type Piperazines.
- Sonepiprazole type Substance100020090.
- Sonepiprazole type SulfaDrug104352070.
- Sonepiprazole type Sulfonamides.
- Sonepiprazole type Vermifuge104528630.
- Sonepiprazole type Drug.
- Sonepiprazole type FunctionalSubstance.
- Sonepiprazole comment "Sonepiprazole (U-101,387, PNU-101,387-G) is a drug of the phenylpiperazine class which acts as a highly selective D4 receptor antagonist. In animals, unlike D2 receptor antagonists like haloperidol, sonepiprazole does not block the behavioral effects of amphetamine or apomorphine, does not alter spontaneous locomotor activity on its own, and lacks extrapyramidal and neuroendocrine effects.".
- Sonepiprazole label "Sonepiprazole".
- Sonepiprazole sameAs m.0bwk5h8.
- Sonepiprazole sameAs Q7560929.
- Sonepiprazole sameAs Q7560929.
- Sonepiprazole sameAs Sonepiprazole.
- Sonepiprazole wasDerivedFrom Sonepiprazole?oldid=593073610.
- Sonepiprazole depiction Sonepiprazole.png.
- Sonepiprazole isPrimaryTopicOf Sonepiprazole.