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- Stimulator_of_interferon_genes abstract "Stimulator of interferon genes (STING), also known transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the TMEM173 gene.STING plays an important role in innate immunity. STING induces type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites. Type I interferon, mediated by STING, protects infected cells and nearby cells from local infection in an autocrine and paracrine manner.STING is encoded by the TMEM173 gene. It works as both a direct cytosolic DNA sensor (CDS) and an adaptor protein in Type I interferon signaling through different molecular mechanisms. It has been shown to activate downstream transcription factors STAT6 and IRF3 through TBK1, which are responsible for antiviral response and innate immune response against intracellular pathogen.".
- Stimulator_of_interferon_genes entrezgene "340061".
- Stimulator_of_interferon_genes thumbnail HSTING_protein_architecture.png?width=300.
- Stimulator_of_interferon_genes wikiPageID "39226476".
- Stimulator_of_interferon_genes wikiPageRevisionID "593098332".
- Stimulator_of_interferon_genes subject Category:Immune_system.
- Stimulator_of_interferon_genes subject Category:Intracellular_receptors.
- Stimulator_of_interferon_genes type Biomolecule.
- Stimulator_of_interferon_genes type Protein.
- Stimulator_of_interferon_genes type BiologicalObject.
- Stimulator_of_interferon_genes comment "Stimulator of interferon genes (STING), also known transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the TMEM173 gene.STING plays an important role in innate immunity. STING induces type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites.".
- Stimulator_of_interferon_genes label "Stimulator of interferon genes".
- Stimulator_of_interferon_genes sameAs m.0tkk9l7.
- Stimulator_of_interferon_genes sameAs Q17157195.
- Stimulator_of_interferon_genes sameAs Q17157195.
- Stimulator_of_interferon_genes wasDerivedFrom Stimulator_of_interferon_genes?oldid=593098332.
- Stimulator_of_interferon_genes depiction HSTING_protein_architecture.png.
- Stimulator_of_interferon_genes isPrimaryTopicOf Stimulator_of_interferon_genes.