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- Suspension_array_technology abstract "Suspension Array Technology (or SAT) is a high throughput, large-scale, and multiplexed screening platform used in molecular biology. SAT has been widely applied to genomic and proteomic research, such as single nucleotide polymorphism (SNP) genotyping, genetic disease screening, gene expression profiling, screening drug discovery and clinical diagnosis. SAT uses microsphere beads (5.6 um in diameter) to prepare arrays. SAT allows for the simultaneous testing of multiple gene variants through the use of these microsphere beads as each type of microsphere bead has a unique identification based on variations in optical properties, most common is fluorescent colour. As each colour and intensity of colour has a unique wavelength, beads can easily be differentiated based on their wavelength intensity. Microspheres are readily suspendable in solution and exhibit favorable kinetics during an assay. Similar to flat microarrays (e.g. DNA microarray), an appropriate receptor molecule, such as DNA oligonucleotide probes, antibodies, or other proteins, attach themselves to the differently labeled microspheres. This produces thousands of microsphere array elements. Probe-target hybridization is usually detected by optically labeled targets, which determines the relative abundance of each target in the sample.".
- Suspension_array_technology thumbnail Suspension_array.jpg?width=300.
- Suspension_array_technology wikiPageExternalLink www.luminexcorp.com.
- Suspension_array_technology wikiPageID "30990996".
- Suspension_array_technology wikiPageRevisionID "579778945".
- Suspension_array_technology hasPhotoCollection Suspension_array_technology.
- Suspension_array_technology subject Category:Bioinformatics.
- Suspension_array_technology subject Category:DNA.
- Suspension_array_technology subject Category:Gene_expression.
- Suspension_array_technology subject Category:Microarrays.
- Suspension_array_technology subject Category:Microtechnology.
- Suspension_array_technology subject Category:Molecular_biology_techniques.
- Suspension_array_technology type Ability105616246.
- Suspension_array_technology type Abstraction100002137.
- Suspension_array_technology type Cognition100023271.
- Suspension_array_technology type Know-how105616786.
- Suspension_array_technology type Method105660268.
- Suspension_array_technology type MolecularBiologyTechniques.
- Suspension_array_technology type PsychologicalFeature100023100.
- Suspension_array_technology type Technique105665146.
- Suspension_array_technology comment "Suspension Array Technology (or SAT) is a high throughput, large-scale, and multiplexed screening platform used in molecular biology. SAT has been widely applied to genomic and proteomic research, such as single nucleotide polymorphism (SNP) genotyping, genetic disease screening, gene expression profiling, screening drug discovery and clinical diagnosis. SAT uses microsphere beads (5.6 um in diameter) to prepare arrays.".
- Suspension_array_technology label "Suspension array technology".
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- Suspension_array_technology sameAs Suspension_array_technology.
- Suspension_array_technology wasDerivedFrom Suspension_array_technology?oldid=579778945.
- Suspension_array_technology depiction Suspension_array.jpg.
- Suspension_array_technology isPrimaryTopicOf Suspension_array_technology.