Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Susumu_Tonegawa> ?p ?o. }
- Susumu_Tonegawa abstract "Susumu Tonegawa (利根川 進 Tonegawa Susumu, born September 6, 1939) is a Japanese scientist who won the Nobel Prize for Physiology or Medicine in 1987 for his discovery of the genetic mechanism that produces antibody diversity. Although he won the Nobel Prize for his work in immunology, Tonegawa is a molecular biologist by training. In his later years, he has turned his attention to the molecular and cellular basis of memory formation.Tonegawa is best known for figuring out the genetic mechanism of the adaptive immune system. One early idea was that each gene produces one protein. There are under 19,000 genes in the human body. However, the human body can produce millions of antibodies. Tonegawa showed in experiments beginning in 1976, genetic material rearranges itself to form millions of antibodies. Comparing the DNA of B cells (a type of white blood cell) in embryonic and adult mice, he observed that genes in the mature B cells of the adult mice are moved around, recombined, and deleted to form the diversity of the variable region of antibodies.[citation needed]Tonegawa was born in Nagoya, Japan and attended the Hibiya High School in Tokyo. He received his bachelor's degree from Kyoto University in 1963. He received his doctorate from the University of California, San Diego where he worked with Dr Masaki Hayashi. He did post-doctoral work at the Salk Institute in San Diego in the laboratory of Renato Dulbecco, then worked at the Basel Institute for Immunology in Basel, Switzerland, where he performed his landmark immunology experiments. In 1981, he became a professor at the Massachusetts Institute of Technology, and founded and directed what is now called the Picower Institute for Learning and Memory at MIT. In 1982, he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Barbara McClintock, another Nobel Prize winner in 1983. He is a member of the Scientific Board of Governors at The Scripps Research Institute. He is currently the director of the RIKEN-MIT Center for Neural Circuit Genetics at MIT. While he heads a full research laboratory at MIT, as of April 1, 2009, he serves as the director of the RIKEN Brain Science Institute (BSI) in Wako-shi, Japan.His son Satto committed suicide in his dorm room on October 24, 2011 while attending MIT.Recently a research report published by his group showed that the activation of a specific sub-population of neurons, labeled during fear conditioning paradigm, is sufficient to evoke a behavioural response correlated with a precise memory trace. This shows for the first time that the activation of a specific engram recalls memory itself.".
- Susumu_Tonegawa academicAdvisor Renato_Dulbecco.
- Susumu_Tonegawa almaMater Kyoto_University.
- Susumu_Tonegawa almaMater Salk_Institute_for_Biological_Studies.
- Susumu_Tonegawa almaMater University_of_California,_San_Diego.
- Susumu_Tonegawa award Louisa_Gross_Horwitz_Prize.
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- Susumu_Tonegawa birthDate "1939-09-06".
- Susumu_Tonegawa birthPlace Nagoya.
- Susumu_Tonegawa birthYear "1939".
- Susumu_Tonegawa field Genetics.
- Susumu_Tonegawa field Immunology.
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- Susumu_Tonegawa knownFor Antibody.
- Susumu_Tonegawa nationality Japan.
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- Susumu_Tonegawa academicAdvisors Renato_Dulbecco.
- Susumu_Tonegawa almaMater Kyoto_University.
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- Susumu_Tonegawa birthDate "1939-09-06".
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- Susumu_Tonegawa caption "Susumu Tonegawa".
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- Susumu_Tonegawa fields Genetics.
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- Susumu_Tonegawa knownFor "Antibody diversity".
- Susumu_Tonegawa name "Susumu Tonegawa".
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- Susumu_Tonegawa nationality Japan.
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- Susumu_Tonegawa prizes "Louisa Gross Horwitz Prize in 1982, Nobel Prize for Physiology or Medicine in 1987".
- Susumu_Tonegawa shortDescription "Japanese biologist".
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