Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Synthetic_genetic_array> ?p ?o. }
Showing items 1 to 15 of
15
with 100 items per page.
- Synthetic_genetic_array abstract "Synthetic Genetic Array analysis (SGA) is a high-throughput technique for exploring synthetic lethal and synthetic sick genetic interactions (SSL). SGA allows for the systematic construction of double mutants using a combination of recombinant genetic techniques, mating and selection steps. Using SGA methodology a query gene deletion mutant can be crossed to an entire genome deletion set to identify any SSL interactions, yielding functional information of the query gene and the genes it interacts with. A large-scale application of SGA in which ~130 query genes were crossed to the set of ~5000 viable deletion mutants in yeast revealed a genetic network containing ~1000 genes and ~4000 SSL interactions. The results of this study showed that genes with similar function tend to interact with one another and genes with similar patterns of genetic interactions often encode products that tend to work in the same pathway or complex. Synthetic Genetic Array analysis was initially developed using the model organism S.cerevisiae. This method has since been extended to cover 30% of the S. cerevisiae genome. Methodology has since been developed to allow SGA analysis in S.pombe and E.coli.".
- Synthetic_genetic_array thumbnail Yeast_colonies_array_1536_format.jpg?width=300.
- Synthetic_genetic_array wikiPageID "18844051".
- Synthetic_genetic_array wikiPageRevisionID "557180984".
- Synthetic_genetic_array hasPhotoCollection Synthetic_genetic_array.
- Synthetic_genetic_array subject Category:Genetics.
- Synthetic_genetic_array subject Category:Microarrays.
- Synthetic_genetic_array comment "Synthetic Genetic Array analysis (SGA) is a high-throughput technique for exploring synthetic lethal and synthetic sick genetic interactions (SSL). SGA allows for the systematic construction of double mutants using a combination of recombinant genetic techniques, mating and selection steps.".
- Synthetic_genetic_array label "Synthetic genetic array".
- Synthetic_genetic_array sameAs m.04gmswd.
- Synthetic_genetic_array sameAs Q7662758.
- Synthetic_genetic_array sameAs Q7662758.
- Synthetic_genetic_array wasDerivedFrom Synthetic_genetic_array?oldid=557180984.
- Synthetic_genetic_array depiction Yeast_colonies_array_1536_format.jpg.
- Synthetic_genetic_array isPrimaryTopicOf Synthetic_genetic_array.