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- TCEB1 abstract "Transcription elongation factor B polypeptide 1 is a protein that in humans is encoded by the TCEB1 gene.This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.".
- TCEB1 entrezgene "6921".
- TCEB1 wikiPageID "14164857".
- TCEB1 wikiPageRevisionID "602199462".
- TCEB1 hasPhotoCollection TCEB1.
- TCEB1 requireManualInspection "no".
- TCEB1 summaryText "This gene encodes the protein elongin C, which is a subunit of the transcription factor B complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.".
- TCEB1 updateCitations "yes".
- TCEB1 updatePage "yes".
- TCEB1 updateProteinBox "yes".
- TCEB1 updateSummary "yes".
- TCEB1 type Biomolecule.
- TCEB1 type Protein.
- TCEB1 type BiologicalObject.
- TCEB1 comment "Transcription elongation factor B polypeptide 1 is a protein that in humans is encoded by the TCEB1 gene.This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.".
- TCEB1 label "TCEB1".
- TCEB1 sameAs m.03cwl5k.
- TCEB1 sameAs Q7669667.
- TCEB1 sameAs Q7669667.
- TCEB1 wasDerivedFrom TCEB1?oldid=602199462.
- TCEB1 isPrimaryTopicOf TCEB1.