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- Tafenoquine abstract "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days. The main advantage of tafenoquine is that it has a long half-life (2–3 weeks) and therefore a single treatment may be sufficient to clear hypnozoites. The shorter regimen has been described as an advantage.Like primaquine, tafenoquine causes hemolysis in people with G-6-P deficiency. Indeed, the long half-life of tafenoquine suggests that particular care should be taken to ensure that individuals with severe G-6-P deficiency do not receive the drug.The dose of tafenoquine has not been firmly established, but for the treatment of Plasmodium vivax malaria, a dose of 800 mg over three days has been used.".
- Tafenoquine atcPrefix "none".
- Tafenoquine casNumber "106635-80-7".
- Tafenoquine fdaUniiCode "262P8GS9L9".
- Tafenoquine iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Tafenoquine pubchem "115358".
- Tafenoquine thumbnail Tafenoquine.svg?width=300.
- Tafenoquine wikiPageID "8955612".
- Tafenoquine wikiPageRevisionID "606545460".
- Tafenoquine atcPrefix "none".
- Tafenoquine c "24".
- Tafenoquine casNumber "106635".
- Tafenoquine chembl "298470".
- Tafenoquine chemspiderid "103196".
- Tafenoquine f "3".
- Tafenoquine h "28".
- Tafenoquine hasPhotoCollection Tafenoquine.
- Tafenoquine inchi "1".
- Tafenoquine inchikey "LBHLFPGPEGDCJG-UHFFFAOYAE".
- Tafenoquine iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Tafenoquine molecularWeight "463.493".
- Tafenoquine n "3".
- Tafenoquine niaidChemdb "6901".
- Tafenoquine o "3".
- Tafenoquine pubchem "115358".
- Tafenoquine smiles "FCc3ccccc3".
- Tafenoquine stdinchi "1".
- Tafenoquine stdinchikey "LBHLFPGPEGDCJG-UHFFFAOYSA-N".
- Tafenoquine synonyms "Etaquine, WR 238605, SB-252263".
- Tafenoquine unii "262".
- Tafenoquine verifiedfields "changed".
- Tafenoquine verifiedrevid "470476706".
- Tafenoquine subject Category:Antimalarial_agents.
- Tafenoquine subject Category:Organofluorides.
- Tafenoquine subject Category:Phenol_ethers.
- Tafenoquine subject Category:Quinolines.
- Tafenoquine type Abstraction100002137.
- Tafenoquine type Element114840755.
- Tafenoquine type Matter100020827.
- Tafenoquine type Part113809207.
- Tafenoquine type PhenolEthers.
- Tafenoquine type PhysicalEntity100001930.
- Tafenoquine type Quintessence114847103.
- Tafenoquine type Relation100031921.
- Tafenoquine type Substance100019613.
- Tafenoquine type Drug.
- Tafenoquine type DrugProduct.
- Tafenoquine type FunctionalSubstance.
- Tafenoquine comment "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days.".
- Tafenoquine label "Tafenoquin".
- Tafenoquine label "Tafenoquine".
- Tafenoquine label "Tafenoquine".
- Tafenoquine sameAs Tafenoquin.
- Tafenoquine sameAs Tafenoquine.
- Tafenoquine sameAs m.027r3kh.
- Tafenoquine sameAs Q2387553.
- Tafenoquine sameAs Q2387553.
- Tafenoquine sameAs Tafenoquine.
- Tafenoquine wasDerivedFrom Tafenoquine?oldid=606545460.
- Tafenoquine depiction Tafenoquine.svg.
- Tafenoquine isPrimaryTopicOf Tafenoquine.