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- Thioester-containing_protein_1 abstract "Thioester containing protein 1, often simply referred to as TEP1 is a key component of the arthropod innate immune system. TEP1 was first identified as a key immunity gene in 2001 through functional studies on Anopheles gambiae mosquitoes.TEP1 is an antimicrobial protein which acts in a system reminiscent of the human complement pathway, which damages the cell membranes of pathogens. Studies have shown that TEP1 is structurally and functionally homologous to the human complement protein C3. TEP1 is now known to be important in the resistance of Anopheles mosquitoes to Plasmodium infection, targeting the malaria parasite during its invasion into the mosquitoes body cavity. Following this discovery insect thioester containing proteins have come under increased scrutiny from the scientific community as possible targets for disease control.TEP1 is coded for by two different alleles TEP1-S and TEP-R which are specific to susceptible and resistant mosquito populations respectively.".
- Thioester-containing_protein_1 thumbnail Thioester.png?width=300.
- Thioester-containing_protein_1 wikiPageExternalLink research.
- Thioester-containing_protein_1 wikiPageExternalLink research.
- Thioester-containing_protein_1 wikiPageID "42325581".
- Thioester-containing_protein_1 wikiPageRevisionID "604309353".
- Thioester-containing_protein_1 entrezgene "2828233".
- Thioester-containing_protein_1 name "Thioester-containing protein 1".
- Thioester-containing_protein_1 organism "Anopheles gambia".
- Thioester-containing_protein_1 refseqprotein "NP_523578.1".
- Thioester-containing_protein_1 symbol "TEP1".
- Thioester-containing_protein_1 taxid "7165".
- Thioester-containing_protein_1 uniprot "B5AZK7".
- Thioester-containing_protein_1 comment "Thioester containing protein 1, often simply referred to as TEP1 is a key component of the arthropod innate immune system. TEP1 was first identified as a key immunity gene in 2001 through functional studies on Anopheles gambiae mosquitoes.TEP1 is an antimicrobial protein which acts in a system reminiscent of the human complement pathway, which damages the cell membranes of pathogens. Studies have shown that TEP1 is structurally and functionally homologous to the human complement protein C3.".
- Thioester-containing_protein_1 label "Thioester-containing protein 1".
- Thioester-containing_protein_1 sameAs m.0102cw6k.
- Thioester-containing_protein_1 sameAs Q17156945.
- Thioester-containing_protein_1 sameAs Q17156945.
- Thioester-containing_protein_1 wasDerivedFrom Thioester-containing_protein_1?oldid=604309353.
- Thioester-containing_protein_1 depiction Thioester.png.
- Thioester-containing_protein_1 isPrimaryTopicOf Thioester-containing_protein_1.
