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- Thumb_hypoplasia abstract "Thumb hypoplasia is a spectrum of congenital abnormalities of the thumb varying from small defects to complete absence of the thumb. It can be isolated, when only the thumb is affected, and in 59% of the cases it is associated with radial dysplasia (or radial club, radius dysplasia, longitudinal radial deficiency). Radial dysplasia is the condition in which the forearm bone and the soft tissues on the thumb side are underdeveloped or absent.In an embryo the upper extremities develop from week four of the gestation. During the fifth to eighth week the thumb will further develop. In this period something goes wrong with the growth of the thumb but the exact cause of thumb hypoplasia is unknown.One out of every 100,000 live births shows thumb hypoplasia. In more than 50% of the cases both hands are affected, otherwise mainly the right hand is affected.About 86% of the children with hypoplastic thumb have associated abnormalities. Embryological hand development occurs simultaneously with growth and development of the cardiovascular, neurologic and hematopoietic systems. Thumb hypoplasia has been described in 30 syndromes wherein those abnormalities have been seen. A syndrome is a combination of three or more abnormalities. Examples of syndromes with an hypoplastic thumb are Holt-Oram syndrome, VACTERL association and thrombocytopenia absent radius (TAR) syndrome.".
- Thumb_hypoplasia thumbnail Thumb_hypoplasia_type_2.png?width=300.
- Thumb_hypoplasia wikiPageExternalLink ?lang=en.
- Thumb_hypoplasia wikiPageID "29396608".
- Thumb_hypoplasia wikiPageRevisionID "583147894".
- Thumb_hypoplasia align "center".
- Thumb_hypoplasia caption "Type II".
- Thumb_hypoplasia caption "Type III-A".
- Thumb_hypoplasia caption "Type III-B".
- Thumb_hypoplasia caption "Type IV".
- Thumb_hypoplasia caption "Type V".
- Thumb_hypoplasia direction "horizontal".
- Thumb_hypoplasia hasPhotoCollection Thumb_hypoplasia.
- Thumb_hypoplasia image "Thumb hypoplasia type 2.png".
- Thumb_hypoplasia image "Thumb hypoplasia type 3a.png".
- Thumb_hypoplasia image "Thumb hypoplasia type 3b.jpg".
- Thumb_hypoplasia image "Thumb hypoplasia type 4.jpg".
- Thumb_hypoplasia image "Thumb hypoplasia type 5.png".
- Thumb_hypoplasia width "(150 * 200 / 302) round 0".
- Thumb_hypoplasia width "(150 * 203 / 315) round 0".
- Thumb_hypoplasia width "(150 * 237 / 352) round 0".
- Thumb_hypoplasia width "(150 * 247 / 368) round 0".
- Thumb_hypoplasia width "(150 * 418 / 274) round 0".
- Thumb_hypoplasia subject Category:Congenital_disorders.
- Thumb_hypoplasia subject Category:Congenital_disorders_of_musculoskeletal_system.
- Thumb_hypoplasia subject Category:Fingers.
- Thumb_hypoplasia subject Category:Plastic_surgery.
- Thumb_hypoplasia subject Category:Rare_diseases.
- Thumb_hypoplasia type Abnormality114501726.
- Thumb_hypoplasia type Abstraction100002137.
- Thumb_hypoplasia type Anomaly114505821.
- Thumb_hypoplasia type Attribute100024264.
- Thumb_hypoplasia type BirthDefect114465048.
- Thumb_hypoplasia type Condition113920835.
- Thumb_hypoplasia type CongenitalDisorders.
- Thumb_hypoplasia type CongenitalDisordersOfMusculoskeletalSystem.
- Thumb_hypoplasia type Defect114464005.
- Thumb_hypoplasia type Imperfection114462666.
- Thumb_hypoplasia type PhysicalCondition114034177.
- Thumb_hypoplasia type State100024720.
- Thumb_hypoplasia comment "Thumb hypoplasia is a spectrum of congenital abnormalities of the thumb varying from small defects to complete absence of the thumb. It can be isolated, when only the thumb is affected, and in 59% of the cases it is associated with radial dysplasia (or radial club, radius dysplasia, longitudinal radial deficiency).".
- Thumb_hypoplasia label "Thumb hypoplasia".
- Thumb_hypoplasia sameAs m.0dr_jfm.
- Thumb_hypoplasia sameAs Q7798809.
- Thumb_hypoplasia sameAs Q7798809.
- Thumb_hypoplasia sameAs Thumb_hypoplasia.
- Thumb_hypoplasia wasDerivedFrom Thumb_hypoplasia?oldid=583147894.
- Thumb_hypoplasia depiction Thumb_hypoplasia_type_2.png.
- Thumb_hypoplasia isPrimaryTopicOf Thumb_hypoplasia.