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- Tianeptine abstract "Coaxil redirects here. For the transmission line for radio frequency signals, see Coaxial cable.Tianeptine (trade names Stablon (AR, AT, BR, FR, IN, ID, MY, MX, PT, SG, TH, TR, VE), Coaxil (CZ, HU, PL, RU, UA), Tatinol (CN), Tianeurax (DE)) is a drug used for treating major depressive episodes (mild, moderate, or severe).It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Formerly it was called a (selective) serotonin reuptake enhancer. Newer research suggests that Tianeptine acts through indirect alteration of AMPA and NMDA glutamate receptor activity and seems to involve altered neuroplasticity and release of BDNF.Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine and its possible interaction with adenosine A1 receptors.Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s. Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; it is also marketed in a number of other European countries under the trade name “Coaxil” as well as in Asia and Latin America as “Stablon” and “Tatinol” but it is not available in Australia, Canada, New Zealand, UK or US.".
- Tianeptine atcPrefix "N06".
- Tianeptine atcSuffix "AX14".
- Tianeptine bioavailability "99.0".
- Tianeptine casNumber "66981-73-5".
- Tianeptine fdaUniiCode "0T493YFU8O".
- Tianeptine iupacName "(RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide".
- Tianeptine pubchem "68870".
- Tianeptine thumbnail Tianeptine2DACS.svg?width=300.
- Tianeptine wikiPageExternalLink www.tianeptine.com.
- Tianeptine wikiPageID "2475030".
- Tianeptine wikiPageRevisionID "606313158".
- Tianeptine atcPrefix "N06".
- Tianeptine atcSuffix "AX14".
- Tianeptine bioavailability "99.0".
- Tianeptine c "21".
- Tianeptine casNumber "66981".
- Tianeptine chembl "1289110".
- Tianeptine chemspiderid "62102".
- Tianeptine cl "1".
- Tianeptine eliminationHalfLife "-32400.0".
- Tianeptine excretion Feces.
- Tianeptine excretion Kidney.
- Tianeptine h "25".
- Tianeptine hasPhotoCollection Tianeptine.
- Tianeptine image "Tianeptine3DanBS.gif".
- Tianeptine inchi "1".
- Tianeptine inchikey "JICJBGPOMZQUBB-UHFFFAOYAW".
- Tianeptine iupacName "-7".
- Tianeptine kegg "D02575".
- Tianeptine legalStatus "Rx-only".
- Tianeptine metabolism Liver.
- Tianeptine molecularWeight "436.953".
- Tianeptine n "2".
- Tianeptine o "4".
- Tianeptine proteinBound "95.0".
- Tianeptine pubchem "68870".
- Tianeptine routesOfAdministration "Oral".
- Tianeptine s "1".
- Tianeptine smiles "Clc1cc2cCNCCCCCCCO".
- Tianeptine stdinchi "1".
- Tianeptine stdinchikey "JICJBGPOMZQUBB-UHFFFAOYSA-N".
- Tianeptine tradename "Coaxil, Stablon".
- Tianeptine unii "0".
- Tianeptine verifiedfields "changed".
- Tianeptine verifiedrevid "455249171".
- Tianeptine width "200".
- Tianeptine subject Category:Dibenzothiazepines.
- Tianeptine subject Category:Euphoriants.
- Tianeptine subject Category:Organochlorides.
- Tianeptine subject Category:Servier.
- Tianeptine subject Category:Tricyclic_antidepressants.
- Tianeptine type Abstraction100002137.
- Tianeptine type Attention105853636.
- Tianeptine type Attraction105850823.
- Tianeptine type Cognition100023271.
- Tianeptine type Concept105835747.
- Tianeptine type Content105809192.
- Tianeptine type Feature105849789.
- Tianeptine type Foil105853924.
- Tianeptine type Idea105833840.
- Tianeptine type Property105849040.
- Tianeptine type PsychologicalFeature100023100.
- Tianeptine type SelectiveSerotoninReuptakeEnhancers.
- Tianeptine type Drug.
- Tianeptine type DrugProduct.
- Tianeptine type FunctionalSubstance.
- Tianeptine comment "Coaxil redirects here. For the transmission line for radio frequency signals, see Coaxial cable.Tianeptine (trade names Stablon (AR, AT, BR, FR, IN, ID, MY, MX, PT, SG, TH, TR, VE), Coaxil (CZ, HU, PL, RU, UA), Tatinol (CN), Tianeurax (DE)) is a drug used for treating major depressive episodes (mild, moderate, or severe).It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties.".
- Tianeptine label "Tianeptin".
- Tianeptine label "Tianeptina".
- Tianeptine label "Tianeptina".
- Tianeptine label "Tianeptine".
- Tianeptine label "Tianeptine".
- Tianeptine label "Tianeptyna".
- Tianeptine label "Тианептин".
- Tianeptine sameAs Tianeptin.
- Tianeptine sameAs Tianeptina.
- Tianeptine sameAs Tianeptine.
- Tianeptine sameAs Tianeptyna.
- Tianeptine sameAs Tianeptina.
- Tianeptine sameAs m.07glsr.
- Tianeptine sameAs Q424260.
- Tianeptine sameAs Q424260.
- Tianeptine sameAs Tianeptine.
- Tianeptine wasDerivedFrom Tianeptine?oldid=606313158.
- Tianeptine depiction Tianeptine2DACS.svg.
- Tianeptine isPrimaryTopicOf Tianeptine.