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- Topoisomerase_inhibitor abstract "Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes (topoisomerase I and II), which are enzymes that control the changes in DNA structure by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle.In recent years, topoisomerases have become popular targets for cancer chemotherapy treatments. It is thought that topoisomerase inhibitors block the ligation step of the cell cycle, generating single and double stranded breaks that harm the integrity of the genome. Introduction of these breaks subsequently leads to apoptosis and cell death.Topoisomerase inhibitors can also function as antibacterial agents. Quinolones have this function.".
- Topoisomerase_inhibitor wikiPageExternalLink NCT01051635.
- Topoisomerase_inhibitor wikiPageID "6688255".
- Topoisomerase_inhibitor wikiPageRevisionID "592686947".
- Topoisomerase_inhibitor hasPhotoCollection Topoisomerase_inhibitor.
- Topoisomerase_inhibitor subject Category:Antibiotics.
- Topoisomerase_inhibitor subject Category:Topoisomerase_inhibitors.
- Topoisomerase_inhibitor type Agent114778436.
- Topoisomerase_inhibitor type Antibacterial102716205.
- Topoisomerase_inhibitor type Antibiotic102716866.
- Topoisomerase_inhibitor type Antibiotics.
- Topoisomerase_inhibitor type CausalAgent100007347.
- Topoisomerase_inhibitor type Drug103247620.
- Topoisomerase_inhibitor type Inhibitor114724436.
- Topoisomerase_inhibitor type Matter100020827.
- Topoisomerase_inhibitor type Medicine103740161.
- Topoisomerase_inhibitor type PhysicalEntity100001930.
- Topoisomerase_inhibitor type Substance100020090.
- Topoisomerase_inhibitor type TopoisomeraseInhibitors.
- Topoisomerase_inhibitor comment "Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes (topoisomerase I and II), which are enzymes that control the changes in DNA structure by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle.In recent years, topoisomerases have become popular targets for cancer chemotherapy treatments.".
- Topoisomerase_inhibitor label "Inhibiteur de topoisomérase".
- Topoisomerase_inhibitor label "Topoisomerase inhibitor".
- Topoisomerase_inhibitor sameAs Inhibiteur_de_topoisomérase.
- Topoisomerase_inhibitor sameAs m.0ghbrm.
- Topoisomerase_inhibitor sameAs Q281044.
- Topoisomerase_inhibitor sameAs Q281044.
- Topoisomerase_inhibitor sameAs Topoisomerase_inhibitor.
- Topoisomerase_inhibitor wasDerivedFrom Topoisomerase_inhibitor?oldid=592686947.
- Topoisomerase_inhibitor isPrimaryTopicOf Topoisomerase_inhibitor.