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- Triclabendazole abstract "Triclabendazole (commercial names: veterinary, liquid: Fasinex; human, tablets: Egaten, both manufactured by Novartis) is a member of the benzimidazole family of anthelmintics. The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group.Triclabendazole was initially only developed as an oral route drug, and displays high efficacy against both immature and adult liver flukes. Benzimidazoles such as triclabendazole are generally accepted to bind to beta-tubulin and prevent the polymerisation of the microtubules of which they are part.Since late 1990s, triclabendazole became available as a generic drug, as patents expired in many countries. Many products were developed then. Among them, Trivantel 15, a 15% triclabendazole suspension, was launched by Agrovet Market Animal Health in the early 2000s. In 2009, the first triclabendazole injectable solution (combined with ivermectin) was developed and launched, also by Agrovet Market Animal Health. The product, Fasiject Plus, a triclabendazole 36% and ivermectin 0.6% solution, is designed to treat infections by Fasciola hepatica (both immature and adult liver flukes), roundworms and ectoparasites, as well.It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.".
- Triclabendazole atcPrefix "P02".
- Triclabendazole atcSuffix "BX04".
- Triclabendazole casNumber "68786-66-3".
- Triclabendazole fdaUniiCode "4784C8E03O".
- Triclabendazole iupacName "5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole".
- Triclabendazole pubchem "50248".
- Triclabendazole thumbnail Triclabendazole.png?width=300.
- Triclabendazole wikiPageExternalLink triclabenzole.html.
- Triclabendazole wikiPageID "1671629".
- Triclabendazole wikiPageRevisionID "605283311".
- Triclabendazole atcPrefix "P02".
- Triclabendazole atcSuffix "BX04".
- Triclabendazole c "14".
- Triclabendazole casNumber "68786".
- Triclabendazole chembl "1086440".
- Triclabendazole chemspiderid "45565".
- Triclabendazole cl "3".
- Triclabendazole eliminationHalfLife "22".
- Triclabendazole excretion ">95% in faeces, 2% in urine, and < 1% in milk".
- Triclabendazole h "9".
- Triclabendazole hasPhotoCollection Triclabendazole.
- Triclabendazole inchi "1".
- Triclabendazole inchikey "NQPDXQQQCQDHHW-UHFFFAOYAQ".
- Triclabendazole iupacName "5".
- Triclabendazole legalStatus "?".
- Triclabendazole metabolism "oxidation to the sulfone and sulfoxide parent compound".
- Triclabendazole molecularWeight "359.658".
- Triclabendazole n "2".
- Triclabendazole o "1".
- Triclabendazole pregnancyCategory "?".
- Triclabendazole pubchem "50248".
- Triclabendazole routesOfAdministration "?".
- Triclabendazole s "1".
- Triclabendazole smiles "Clc3ccccc3Cl".
- Triclabendazole stdinchi "1".
- Triclabendazole stdinchikey "NQPDXQQQCQDHHW-UHFFFAOYSA-N".
- Triclabendazole unii "4784".
- Triclabendazole verifiedfields "changed".
- Triclabendazole verifiedrevid "470613656".
- Triclabendazole subject Category:Anthelmintics.
- Triclabendazole subject Category:Benzimidazoles.
- Triclabendazole subject Category:Organochlorides.
- Triclabendazole subject Category:Phenol_ethers.
- Triclabendazole subject Category:World_Health_Organization_essential_medicines.
- Triclabendazole type Abstraction100002137.
- Triclabendazole type Cognition100023271.
- Triclabendazole type Content105809192.
- Triclabendazole type Discipline105996646.
- Triclabendazole type Element114840755.
- Triclabendazole type KnowledgeDomain105999266.
- Triclabendazole type LifeScience106037298.
- Triclabendazole type Matter100020827.
- Triclabendazole type MedicalScience106045562.
- Triclabendazole type Medicine106043075.
- Triclabendazole type NaturalScience106000400.
- Triclabendazole type Part113809207.
- Triclabendazole type PhenolEthers.
- Triclabendazole type PhysicalEntity100001930.
- Triclabendazole type PsychologicalFeature100023100.
- Triclabendazole type Quintessence114847103.
- Triclabendazole type Relation100031921.
- Triclabendazole type Science105999797.
- Triclabendazole type Substance100019613.
- Triclabendazole type WorldHealthOrganizationEssentialMedicines.
- Triclabendazole type Drug.
- Triclabendazole type DrugProduct.
- Triclabendazole type FunctionalSubstance.
- Triclabendazole comment "Triclabendazole (commercial names: veterinary, liquid: Fasinex; human, tablets: Egaten, both manufactured by Novartis) is a member of the benzimidazole family of anthelmintics. The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group.Triclabendazole was initially only developed as an oral route drug, and displays high efficacy against both immature and adult liver flukes.".
- Triclabendazole label "Triclabendazol".
- Triclabendazole label "Triclabendazol".
- Triclabendazole label "Triclabendazole".
- Triclabendazole label "Triclabendazool".
- Triclabendazole label "トリクラベンダゾール".
- Triclabendazole sameAs Triklabendazol.
- Triclabendazole sameAs Triclabendazol.
- Triclabendazole sameAs Triclabendazol.
- Triclabendazole sameAs Triclabendazole.
- Triclabendazole sameAs トリクラベンダゾール.
- Triclabendazole sameAs Triclabendazool.
- Triclabendazole sameAs m.05m6w_.
- Triclabendazole sameAs Q419739.
- Triclabendazole sameAs Q419739.
- Triclabendazole sameAs Triclabendazole.
- Triclabendazole wasDerivedFrom Triclabendazole?oldid=605283311.
- Triclabendazole depiction Triclabendazole.png.
- Triclabendazole isPrimaryTopicOf Triclabendazole.