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- Variable_surface_glycoprotein abstract "Variable surface glycoproteins or Variant surface glycoproteins (VSG) are a type of proteins coating the surface of some infectious microorganisms (e.g. Trypanosoma brucei) and helping them to evade the host's immune system by mean of antigenic variation. The VSG protein is a key molecule for immune escape and parasitic success.Combinatorial processes increase the diversity of variable surface glycoproteins. The parasite is expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes. The genes are located in subtelomeric region and are often activated by the duplicative transposition of a silent basic copy gene into an unlinked telomerically located expression site, producing an active expression-linked copy of that gene.".
- Variable_surface_glycoprotein thumbnail Mechanisms_of_VSG_switching2.png?width=300.
- Variable_surface_glycoprotein wikiPageExternalLink vsg.htm.
- Variable_surface_glycoprotein wikiPageID "40081998".
- Variable_surface_glycoprotein wikiPageRevisionID "593274082".
- Variable_surface_glycoprotein altsymbols "Tb05.26C7.380".
- Variable_surface_glycoprotein altsymbols "VSG 221".
- Variable_surface_glycoprotein chromosome "5".
- Variable_surface_glycoprotein entrezchromosome "NC_007278.1".
- Variable_surface_glycoprotein entrezgene "3657576".
- Variable_surface_glycoprotein genlocEnd "1409671".
- Variable_surface_glycoprotein genlocStart "1408247".
- Variable_surface_glycoprotein name "Variable surface glycoprotein".
- Variable_surface_glycoprotein name "Variant surface glycoprotein MITAT 1.2".
- Variable_surface_glycoprotein organism "Trypanosoma brucei".
- Variable_surface_glycoprotein symbol "Tb927.5.4730".
- Variable_surface_glycoprotein taxid "999953".
- Variable_surface_glycoprotein uniprot "P26332".
- Variable_surface_glycoprotein subject Category:Glycoproteins.
- Variable_surface_glycoprotein subject Category:Protist_proteins.
- Variable_surface_glycoprotein comment "Variable surface glycoproteins or Variant surface glycoproteins (VSG) are a type of proteins coating the surface of some infectious microorganisms (e.g. Trypanosoma brucei) and helping them to evade the host's immune system by mean of antigenic variation. The VSG protein is a key molecule for immune escape and parasitic success.Combinatorial processes increase the diversity of variable surface glycoproteins.".
- Variable_surface_glycoprotein label "Variable surface glycoprotein".
- Variable_surface_glycoprotein sameAs m.0wkr79f.
- Variable_surface_glycoprotein sameAs Q17156539.
- Variable_surface_glycoprotein sameAs Q17156539.
- Variable_surface_glycoprotein wasDerivedFrom Variable_surface_glycoprotein?oldid=593274082.
- Variable_surface_glycoprotein depiction Mechanisms_of_VSG_switching2.png.
- Variable_surface_glycoprotein isPrimaryTopicOf Variable_surface_glycoprotein.
