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- Vedaclidine abstract "Vedaclidine (LY-297,802, NNC 11-1053) is a novel analgesic drug which acts as a mixed agonist–antagonist at muscarinic acetylcholine receptors, being a potent and selective agonist for the M1 and M4 subtypes, yet an antagonist at the M2, M3 and M5 subtypes. It is orally active and an effective analgesic over 3x the potency of morphine, with side effects such as salivation and tremor only occurring at many times the effective analgesic dose. Human trials showed little potential for development of dependence or abuse, and research is continuing into possible clinical application in the treatment of neuropathic pain and cancer pain relief.".
- Vedaclidine atcPrefix "None".
- Vedaclidine casNumber "141575-52-2".
- Vedaclidine fdaUniiCode "98IW5HAV1N".
- Vedaclidine iupacName "(3-(3-1-Butylthio)-1,2,5-thiadiazol-4-yl)-1-azabicyclo[2.2.2]octane".
- Vedaclidine pubchem "60868".
- Vedaclidine thumbnail Vedaclidine.png?width=300.
- Vedaclidine wikiPageID "19612974".
- Vedaclidine wikiPageRevisionID "600817456".
- Vedaclidine atcPrefix "None".
- Vedaclidine c "13".
- Vedaclidine casNumber "141575".
- Vedaclidine chemspiderid "54852".
- Vedaclidine h "21".
- Vedaclidine hasPhotoCollection Vedaclidine.
- Vedaclidine iupacName "-1".
- Vedaclidine molecularWeight "283.455".
- Vedaclidine n "3".
- Vedaclidine pubchem "60868".
- Vedaclidine s "2".
- Vedaclidine smiles "C3CC1CCN3CC1c2nsnc2SCCCC".
- Vedaclidine unii "98".
- Vedaclidine subject Category:Muscarinic_agonists.
- Vedaclidine subject Category:Muscarinic_antagonists.
- Vedaclidine subject Category:Quinuclidines.
- Vedaclidine subject Category:Thiadiazoles.
- Vedaclidine subject Category:Thioethers.
- Vedaclidine type Adversary109773245.
- Vedaclidine type CausalAgent100007347.
- Vedaclidine type LivingThing100004258.
- Vedaclidine type MuscarinicAntagonists.
- Vedaclidine type Object100002684.
- Vedaclidine type Organism100004475.
- Vedaclidine type Person100007846.
- Vedaclidine type PhysicalEntity100001930.
- Vedaclidine type Whole100003553.
- Vedaclidine type YagoLegalActor.
- Vedaclidine type YagoLegalActorGeo.
- Vedaclidine type Drug.
- Vedaclidine type DrugProduct.
- Vedaclidine type FunctionalSubstance.
- Vedaclidine comment "Vedaclidine (LY-297,802, NNC 11-1053) is a novel analgesic drug which acts as a mixed agonist–antagonist at muscarinic acetylcholine receptors, being a potent and selective agonist for the M1 and M4 subtypes, yet an antagonist at the M2, M3 and M5 subtypes. It is orally active and an effective analgesic over 3x the potency of morphine, with side effects such as salivation and tremor only occurring at many times the effective analgesic dose.".
- Vedaclidine label "Vedaclidine".
- Vedaclidine sameAs ベダクリジン.
- Vedaclidine sameAs m.04n6chb.
- Vedaclidine sameAs Q7917897.
- Vedaclidine sameAs Q7917897.
- Vedaclidine sameAs Vedaclidine.
- Vedaclidine wasDerivedFrom Vedaclidine?oldid=600817456.
- Vedaclidine depiction Vedaclidine.png.
- Vedaclidine isPrimaryTopicOf Vedaclidine.