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- Velusetrag abstract "Velusetrag (USAN; TD-5108) is an experimental drug candidate for the treatment of chronic constipation and irritable bowel syndrome. It is a potent, selective, high efficacy 5-HT4 receptor agonist.In clinical trials, velusetrag was efficacious and well tolerated in patients with chronic constipation, and showed accelerated intestinal and colonic transit after single dosing and accelerated gastric emptying after multiple dosing.".
- Velusetrag atcPrefix "None".
- Velusetrag casNumber "866933-46-2".
- Velusetrag casSupplemental "866933-51-9 (hydrochloride)".
- Velusetrag iupacName "N-[8-[(2R)-2-hydroxy-3-[methyl(methylsulfonyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide".
- Velusetrag pubchem "53297466".
- Velusetrag thumbnail Velusetrag.svg?width=300.
- Velusetrag wikiPageID "32625467".
- Velusetrag wikiPageRevisionID "600832745".
- Velusetrag atcPrefix "None".
- Velusetrag c "25".
- Velusetrag casNumber "866933".
- Velusetrag casSupplemental "866933".
- Velusetrag h "36".
- Velusetrag hasPhotoCollection Velusetrag.
- Velusetrag image "Velusetrag2.png".
- Velusetrag inchi "InChI=1S/C25H36N4O5S/c1-1629-23-8-6-5-7-1711-222426-18-12-19-9-10-202815-2114-273534/h5-8,11,16,18-21,30H,9-10,12-15H2,1-4H3,/t18?,19?,20?,21-/m0/s1".
- Velusetrag inchikey "HXLOHDZQBKCUCR-FNNAPWSISA-N".
- Velusetrag iupacName "N-[8-[-2-hydroxy-3-[methylamino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide".
- Velusetrag molecularWeight "504.642".
- Velusetrag n "4".
- Velusetrag o "5".
- Velusetrag pubchem "53297466".
- Velusetrag s "1".
- Velusetrag smiles "CCN1C2=CC=CC=C2C=CCNC3CC4CCCN4CCO".
- Velusetrag subject Category:Motility_stimulants.
- Velusetrag subject Category:Quinolones.
- Velusetrag subject Category:Serotonin_receptor_agonists.
- Velusetrag subject Category:Sulfonamides.
- Velusetrag subject Category:Tropanes.
- Velusetrag type Abstraction100002137.
- Velusetrag type Cognition100023271.
- Velusetrag type Information105816287.
- Velusetrag type MotilityStimulants.
- Velusetrag type PsychologicalFeature100023100.
- Velusetrag type Stimulation105827684.
- Velusetrag type Drug.
- Velusetrag type FunctionalSubstance.
- Velusetrag comment "Velusetrag (USAN; TD-5108) is an experimental drug candidate for the treatment of chronic constipation and irritable bowel syndrome. It is a potent, selective, high efficacy 5-HT4 receptor agonist.In clinical trials, velusetrag was efficacious and well tolerated in patients with chronic constipation, and showed accelerated intestinal and colonic transit after single dosing and accelerated gastric emptying after multiple dosing.".
- Velusetrag label "Velusetrag".
- Velusetrag sameAs m.0h1h29m.
- Velusetrag sameAs Q7919353.
- Velusetrag sameAs Q7919353.
- Velusetrag sameAs Velusetrag.
- Velusetrag wasDerivedFrom Velusetrag?oldid=600832745.
- Velusetrag depiction Velusetrag.svg.
- Velusetrag isPrimaryTopicOf Velusetrag.