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- Verrucarin_A abstract "Verrucarin A belongs in the class of trichothecenes, a group of sesquiterpene toxins produced by several fungi, namely from the Fusarium species, that are responsible for infecting food grains. Within the skeleton of the basic trichothecane structure, the olefin and epoxide are crucial for toxicity; ester functionalities and hydroxyl groups often contribute to the toxicity, thereby rendering Verrucarin A as one of the most lethal examples. The mechanism of action for this class of toxins mainly inhibits protein biosynthesis by preventing peptidyl transferase activity. Although initially thought to be potentially useful as anticancer therapeutics, numerous examples of trichothecene derivatives were shown to be too toxic for clinical use.".
- Verrucarin_A thumbnail Verrucarin_A_structure.png?width=300.
- Verrucarin_A wikiPageID "36122052".
- Verrucarin_A wikiPageRevisionID "599728720".
- Verrucarin_A hasPhotoCollection Verrucarin_A.
- Verrucarin_A subject Category:Sesquiterpenes.
- Verrucarin_A comment "Verrucarin A belongs in the class of trichothecenes, a group of sesquiterpene toxins produced by several fungi, namely from the Fusarium species, that are responsible for infecting food grains. Within the skeleton of the basic trichothecane structure, the olefin and epoxide are crucial for toxicity; ester functionalities and hydroxyl groups often contribute to the toxicity, thereby rendering Verrucarin A as one of the most lethal examples.".
- Verrucarin_A label "Verrucarin A".
- Verrucarin_A sameAs m.0k2gm6k.
- Verrucarin_A sameAs Q7922588.
- Verrucarin_A sameAs Q7922588.
- Verrucarin_A wasDerivedFrom Verrucarin_A?oldid=599728720.
- Verrucarin_A depiction Verrucarin_A_structure.png.
- Verrucarin_A isPrimaryTopicOf Verrucarin_A.