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- Virtual_Physiological_Rat abstract "The Virtual Physiological Rat (VPR) Projectis an international collaboration aimed simulating the integrated cardiovascular function of the rat and supported by the National Institute of General Medical Sciences as a National Center for Systems Biology. The project is motivated by the fact that, although there exist both a depth of knowledge of basic cardiovascular physiology and a host of physiological and genomic data from animal models of disease, we lack an understanding of how multiple genes and environmental factors interact to determine cardiovascular phenotype. The Virtual Physiological Rat Project is focused on developing computational tools to capture the underlying systems physiology as well as the pathophysiological perturbations associated with disease. These tools are being developed and validated based on experimental characterization of physiological function across a number of organ systems in rat strains engineered to show relevant disease phenotypes. Computer simulation is used to integrate disparate data (genomic, anatomic, physiological, etc.) to explain and predict function, and to translate the findings from animal models to yield new information on specific interrelated complex diseases in humans, including hypertension, kidney disease, heart failure, and metabolic syndrome.".
- Virtual_Physiological_Rat wikiPageID "36307309".
- Virtual_Physiological_Rat wikiPageRevisionID "546053411".
- Virtual_Physiological_Rat hasPhotoCollection Virtual_Physiological_Rat.
- Virtual_Physiological_Rat subject Category:Medical_research.
- Virtual_Physiological_Rat comment "The Virtual Physiological Rat (VPR) Projectis an international collaboration aimed simulating the integrated cardiovascular function of the rat and supported by the National Institute of General Medical Sciences as a National Center for Systems Biology.".
- Virtual_Physiological_Rat label "Virtual Physiological Rat".
- Virtual_Physiological_Rat sameAs m.0k28zqb.
- Virtual_Physiological_Rat sameAs Q7935016.
- Virtual_Physiological_Rat sameAs Q7935016.
- Virtual_Physiological_Rat wasDerivedFrom Virtual_Physiological_Rat?oldid=546053411.
- Virtual_Physiological_Rat isPrimaryTopicOf Virtual_Physiological_Rat.