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- Wnt_signaling_pathway abstract "The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell. Three Wnt signaling pathways have been characterized: the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. All three Wnt signaling pathways are activated by the binding of a Wnt-protein ligand to a Frizzled family receptor, which passes the biological signal to the protein Dishevelled inside the cell. The canonical Wnt pathway leads to regulation of gene transcription, the noncanonical planar cell polarity pathway regulates the cytoskeleton that is responsible for the shape of the cell, and the noncanonical Wnt/calcium pathway regulates calcium inside the cell. Wnt signaling pathways use either nearby cell-cell communication (paracrine) or same-cell communication (autocrine). They are highly evolutionarily conserved, meaning they are similar across many species from fruit flies to humans.Wnt signaling was first identified for its role in carcinogenesis, but has since been recognized for its function in embryonic development. The embryonic processes it controls include body axis patterning, cell fate specification, cell proliferation, and cell migration. These processes are necessary for proper formation of important tissues including bone, heart, and muscle. Its role in embryonic development was discovered when genetic mutations in proteins in the Wnt pathway produced abnormal fruit fly embryos. Later research found that the genes responsible for these abnormalities also influenced breast cancer development in mice.The clinical importance of this pathway has been demonstrated by mutations that lead to a variety of diseases, including breast and prostate cancer, glioblastoma, type II diabetes, and others.".
- Wnt_signaling_pathway thumbnail 4f0a_bio_r_500.jpg?width=300.
- Wnt_signaling_pathway wikiPageExternalLink grey-hair-reversed-nyu-scientists-believe-cracked-code-age-reversal-original-color-health-13871716.
- Wnt_signaling_pathway wikiPageExternalLink wntgame.html.
- Wnt_signaling_pathway wikiPageExternalLink www_bget?path:dme04310.
- Wnt_signaling_pathway wikiPageExternalLink www_bget?path:hsa04310.
- Wnt_signaling_pathway wikiPageExternalLink www_bget?path:mmu04310.
- Wnt_signaling_pathway wikiPageExternalLink hsa04310.html.
- Wnt_signaling_pathway wikiPageExternalLink wntpathways.html.
- Wnt_signaling_pathway wikiPageExternalLink search?nm=fzd&x=0&y=0.
- Wnt_signaling_pathway wikiPageExternalLink search?nm=wnt&x=0&y=0.
- Wnt_signaling_pathway wikiPageExternalLink wnt.
- Wnt_signaling_pathway wikiPageID "1209057".
- Wnt_signaling_pathway wikiPageRevisionID "606319727".
- Wnt_signaling_pathway hasPhotoCollection Wnt_signaling_pathway.
- Wnt_signaling_pathway subject Category:Genes.
- Wnt_signaling_pathway subject Category:Signal_transduction.
- Wnt_signaling_pathway type Abstraction100002137.
- Wnt_signaling_pathway type Arrangement107938773.
- Wnt_signaling_pathway type Gene105436752.
- Wnt_signaling_pathway type Genes.
- Wnt_signaling_pathway type Group100031264.
- Wnt_signaling_pathway type Ordering108456993.
- Wnt_signaling_pathway type Sequence108459252.
- Wnt_signaling_pathway type Series108457976.
- Wnt_signaling_pathway comment "The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell. Three Wnt signaling pathways have been characterized: the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway.".
- Wnt_signaling_pathway label "Vía de señalización WNT".
- Wnt_signaling_pathway label "Wnt (protéines)".
- Wnt_signaling_pathway label "Wnt signaling pathway".
- Wnt_signaling_pathway label "Wnt".
- Wnt_signaling_pathway label "Wnt-Signalweg".
- Wnt_signaling_pathway label "Wntシグナル経路".
- Wnt_signaling_pathway label "Wnt信号通路".
- Wnt_signaling_pathway label "Сигнальный путь Wnt".
- Wnt_signaling_pathway sameAs Wnt_signalizace.
- Wnt_signaling_pathway sameAs Wnt-Signalweg.
- Wnt_signaling_pathway sameAs Vía_de_señalización_WNT.
- Wnt_signaling_pathway sameAs Wnt_(protéines).
- Wnt_signaling_pathway sameAs Wntシグナル経路.
- Wnt_signaling_pathway sameAs Wnt.
- Wnt_signaling_pathway sameAs m.04hfk6.
- Wnt_signaling_pathway sameAs Q155769.
- Wnt_signaling_pathway sameAs Q155769.
- Wnt_signaling_pathway sameAs Wnt_signaling_pathway.
- Wnt_signaling_pathway wasDerivedFrom Wnt_signaling_pathway?oldid=606319727.
- Wnt_signaling_pathway depiction 4f0a_bio_r_500.jpg.
- Wnt_signaling_pathway isPrimaryTopicOf Wnt_signaling_pathway.