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- Zidovudine abstract "Zidovudine (INN) or azidothymidine (AZT) (also called ZDV) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. AZT inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming. AZT is the first U.S. government-approved treatment for HIV, marketed under the brand name Retrovir. AZT was the first breakthrough in AIDS therapy, significantly reducing the replication of the virus in patients and leading to clinical and immunologic improvements. It can also be used to prevent HIV transmission, such as from mother to child during the period of birth or after a needle stick injury. Used by itself in HIV-infected patients, AZT slows HIV replication in patients, but does not stop it entirely. HIV may become AZT-resistant over time, and therefore AZT is now usually used in conjunction with other anti-HIV drugs in the combination therapy called highly active antiretroviral therapy (HAART). AZT is included in Combivir and Trizivir, and is included in the World Health Organization's Model List of Essential Medicines, which suggests the minimum medicinal needs for a basic health care system.".
- Zidovudine atcPrefix "J05".
- Zidovudine atcSuffix "AF01".
- Zidovudine casNumber "30516-87-1".
- Zidovudine chEBI "10111".
- Zidovudine drugbank "DB00495".
- Zidovudine fdaUniiCode "4B9XT59T7S".
- Zidovudine iupacName "1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione".
- Zidovudine pubchem "35370".
- Zidovudine thumbnail Zidovudine.svg?width=300.
- Zidovudine wikiPageExternalLink dpdirect.jsp?name=Zidovudine.
- Zidovudine wikiPageID "195187".
- Zidovudine wikiPageRevisionID "605450868".
- Zidovudine atcPrefix "J05".
- Zidovudine atcSuffix "AF01".
- Zidovudine bioavailability "Complete absorption, following first-pass metabolism systemic availability 75%".
- Zidovudine c "10".
- Zidovudine casNumber "30516".
- Zidovudine chebi "10111".
- Zidovudine chembl "129".
- Zidovudine chemspiderid "32555".
- Zidovudine drugbank "DB00495".
- Zidovudine eliminationHalfLife "10800.0".
- Zidovudine excretion Kidney.
- Zidovudine excretion Rectum.
- Zidovudine h "13".
- Zidovudine hasPhotoCollection Zidovudine.
- Zidovudine image "Zidovudine-3D-balls.png".
- Zidovudine inchi "1".
- Zidovudine iupacName "1".
- Zidovudine kegr "D00413".
- Zidovudine legalStatus "Rx-only".
- Zidovudine metabolism Liver.
- Zidovudine molecularWeight "267.242".
- Zidovudine n "5".
- Zidovudine niaidChemdb "1".
- Zidovudine o "4".
- Zidovudine pdbLigand "AZZ".
- Zidovudine pregnancyAu "B3".
- Zidovudine pregnancyUs "C".
- Zidovudine proteinBound "30".
- Zidovudine pubchem "35370".
- Zidovudine routesOfAdministration "Oral, serum, suppository".
- Zidovudine smiles "O=C/1NCN[C@@H]2O[C@@H]CO".
- Zidovudine stdinchi "1".
- Zidovudine stdinchikey "HBOMLICNUCNMMY-XLPZGREQSA-N".
- Zidovudine tradename "Retrovir".
- Zidovudine unii "4".
- Zidovudine verifiedfields "changed".
- Zidovudine verifiedrevid "441946513".
- Zidovudine watchedfields "changed".
- Zidovudine subject Category:Azides.
- Zidovudine subject Category:IARC_Group_2B_carcinogens.
- Zidovudine subject Category:Nucleoside_analog_reverse_transcriptase_inhibitors.
- Zidovudine subject Category:Pyrimidinediones.
- Zidovudine subject Category:Tetrahydrofurans.
- Zidovudine subject Category:World_Health_Organization_essential_medicines.
- Zidovudine type Drug.
- Zidovudine type DrugProduct.
- Zidovudine type FunctionalSubstance.
- Zidovudine comment "Zidovudine (INN) or azidothymidine (AZT) (also called ZDV) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. AZT inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming. AZT is the first U.S. government-approved treatment for HIV, marketed under the brand name Retrovir.".
- Zidovudine label "AZT".
- Zidovudine label "Azydotymidyna".
- Zidovudine label "Zidovudin".
- Zidovudine label "Zidovudina".
- Zidovudine label "Zidovudina".
- Zidovudine label "Zidovudine".
- Zidovudine label "Zidovudine".
- Zidovudine label "Зидовудин".
- Zidovudine label "ジドブジン".
- Zidovudine label "齐多夫定".
- Zidovudine sameAs Zidovudin.
- Zidovudine sameAs Zidovudina.
- Zidovudine sameAs Zidovudine.
- Zidovudine sameAs AZT.
- Zidovudine sameAs ジドブジン.
- Zidovudine sameAs Azydotymidyna.
- Zidovudine sameAs Zidovudina.
- Zidovudine sameAs m.01bqth.
- Zidovudine sameAs Q198504.
- Zidovudine sameAs Q198504.
- Zidovudine sameAs Zidovudine.
- Zidovudine sameAs DB00495.
- Zidovudine sameAs 5726.
- Zidovudine wasDerivedFrom Zidovudine?oldid=605450868.
- Zidovudine depiction Zidovudine.svg.
- Zidovudine isPrimaryTopicOf Zidovudine.