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- Zimelidine abstract "Zimelidine (Zimeldine, Normud, Zelmid) was the first selective serotonin reuptake inhibitor (SSRI) antidepressant to be marketed. It is a pyridylallylamine, and is structurally different from other antidepressants. Zimelidine was developed in the late 1970s and early 1980s by Arvid Carlsson, who was then working for the Swedish company Astra AB. It was discovered following a search for drugs with structures similar to brompheniramine (it is a derivative of brompheniramine), an antihistamine with antidepressant activity. Zimelidine was first sold in 1982.While zilmelidine had a very favorable safety profile, within a year and a half of its introduction, rare case reports of Guillain-Barré syndrome emerged that appeared to be caused by the drug, prompting its manufacturer to withdraw it from the market. After its withdrawal, it was succeeded by fluvoxamine and fluoxetine (derived from the antihistamine diphenhydramine) in that order, and the other SSRIs.".
- Zimelidine atcPrefix "N06".
- Zimelidine atcSuffix "AB02".
- Zimelidine casNumber "56775-88-3".
- Zimelidine casSupplemental "60525-15-7 (anhydrous dihydrochloride), 61129-30-4 (dihydrochloride monohydrate)".
- Zimelidine drugbank "DB04832".
- Zimelidine fdaUniiCode "3J928617DW".
- Zimelidine iupacName "(Z)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-3-yl)prop-2-en-1-amine".
- Zimelidine pubchem "5365247".
- Zimelidine thumbnail Zimelidine_Structural_Formulae_V.1.svg?width=300.
- Zimelidine wikiPageID "2148630".
- Zimelidine wikiPageRevisionID "596045504".
- Zimelidine atcPrefix "N06".
- Zimelidine atcSuffix "AB02".
- Zimelidine bioavailability "?".
- Zimelidine br "1".
- Zimelidine c "16".
- Zimelidine casNumber "56775".
- Zimelidine casSupplemental "60525".
- Zimelidine chembl "37744".
- Zimelidine chemspiderid "4517305".
- Zimelidine drugbank "DB04832".
- Zimelidine eliminationHalfLife "12960.0".
- Zimelidine eliminationHalfLife "7200.0".
- Zimelidine excretion "?".
- Zimelidine h "17".
- Zimelidine hasPhotoCollection Zimelidine.
- Zimelidine inchi "1".
- Zimelidine inchikey "OYPPVKRFBIWMSX-SXGWCWSVBL".
- Zimelidine iupacName "-3".
- Zimelidine legalStatus "Withdrawn worldwide".
- Zimelidine metabolism "?".
- Zimelidine molecularWeight "317.224".
- Zimelidine n "2".
- Zimelidine pregnancyCategory "?".
- Zimelidine pubchem "5365247".
- Zimelidine routesOfAdministration "Oral".
- Zimelidine smiles "Brc2ccccc2".
- Zimelidine stdinchi "1".
- Zimelidine stdinchikey "OYPPVKRFBIWMSX-SXGWCWSVSA-N".
- Zimelidine unii "3".
- Zimelidine verifiedfields "changed".
- Zimelidine verifiedrevid "470635867".
- Zimelidine watchedfields "changed".
- Zimelidine width "220".
- Zimelidine subject Category:Alkenes.
- Zimelidine subject Category:Amines.
- Zimelidine subject Category:Organobromides.
- Zimelidine subject Category:Pyridines.
- Zimelidine subject Category:Selective_serotonin_reuptake_inhibitors.
- Zimelidine subject Category:Withdrawn_drugs.
- Zimelidine type Abstraction100002137.
- Zimelidine type AliphaticCompound114601294.
- Zimelidine type Alkene114713120.
- Zimelidine type Alkenes.
- Zimelidine type Amine114739004.
- Zimelidine type Amines.
- Zimelidine type Base114618253.
- Zimelidine type Chemical114806838.
- Zimelidine type Compound114818238.
- Zimelidine type Material114580897.
- Zimelidine type Matter100020827.
- Zimelidine type MethaneSeries114951377.
- Zimelidine type OrganicCompound114727670.
- Zimelidine type Part113809207.
- Zimelidine type PhysicalEntity100001930.
- Zimelidine type Pyridine114692510.
- Zimelidine type Pyridines.
- Zimelidine type Relation100031921.
- Zimelidine type Substance100019613.
- Zimelidine type Drug.
- Zimelidine type DrugProduct.
- Zimelidine type FunctionalSubstance.
- Zimelidine comment "Zimelidine (Zimeldine, Normud, Zelmid) was the first selective serotonin reuptake inhibitor (SSRI) antidepressant to be marketed. It is a pyridylallylamine, and is structurally different from other antidepressants. Zimelidine was developed in the late 1970s and early 1980s by Arvid Carlsson, who was then working for the Swedish company Astra AB.".
- Zimelidine label "Zimelidin".
- Zimelidine label "Zimelidine".
- Zimelidine label "Zimelidine".
- Zimelidine label "Zimelidine".
- Zimelidine label "Зимелидин".
- Zimelidine sameAs Zimelidin.
- Zimelidine sameAs Zimelidine.
- Zimelidine sameAs Zimelidine.
- Zimelidine sameAs m.06qc6y.
- Zimelidine sameAs Q203483.
- Zimelidine sameAs Q203483.
- Zimelidine sameAs DB04832.
- Zimelidine sameAs Zimelidine.
- Zimelidine wasDerivedFrom Zimelidine?oldid=596045504.
- Zimelidine depiction Zimelidine_Structural_Formulae_V.1.svg.
- Zimelidine isPrimaryTopicOf Zimelidine.