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- 5-APB abstract "5-(2-aminopropyl)benzofuran or 1-benzofuran-5-ylpropan-2-amine (5-APB) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2A and 5-HT2B receptors (Ki of 14nM at 5-HT2B). This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. The subjective effects and structure-activity relationship suggest that 5-APB is also a monoamine releasing agent. Preliminary evidence suggests 5-APB is an inhibitor of the CYP2D6 enzyme.5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass and doses should be adjusted accordingly. 5-APB is also an agonist of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor. It has been sold as a designer drug since 2010. Anecdotal reports from users suggest it has stimulant and empathogenic effects, but less psychedelic action than related compounds such as 6-APB and 5-APDB.".
- 5-APB atcPrefix "none".
- 5-APB casNumber "286834-80-8".
- 5-APB iupacName "5-(2-aminopropyl)benzofuran".
- 5-APB pubchem "9837232".
- 5-APB thumbnail 5-APB2DACS.svg?width=300.
- 5-APB wikiPageID "31136906".
- 5-APB wikiPageRevisionID "603272519".
- 5-APB atcPrefix "none".
- 5-APB c "11".
- 5-APB casNumber "286834".
- 5-APB chemspiderid "8012953".
- 5-APB h "13".
- 5-APB hasPhotoCollection 5-APB.
- 5-APB inchi "1".
- 5-APB inchikey "VKUMKUZDZWHMQU-UHFFFAOYAQ".
- 5-APB iupacName "5".
- 5-APB legalStatus "Class B".
- 5-APB molecularWeight "175.23".
- 5-APB n "1".
- 5-APB o "1".
- 5-APB pregnancyCategory "?".
- 5-APB pubchem "9837232".
- 5-APB smiles "CCCC1=CC=C2C=C1".
- 5-APB stdinchi "1".
- 5-APB stdinchikey "VKUMKUZDZWHMQU-UHFFFAOYSA-N".
- 5-APB verifiedfields "changed".
- 5-APB verifiedrevid "458140931".
- 5-APB subject Category:Amphetamines.
- 5-APB subject Category:Benzofurans.
- 5-APB subject Category:Designer_drugs.
- 5-APB type Drug.
- 5-APB type FunctionalSubstance.
- 5-APB comment "5-(2-aminopropyl)benzofuran or 1-benzofuran-5-ylpropan-2-amine (5-APB) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2A and 5-HT2B receptors (Ki of 14nM at 5-HT2B). This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA.".
- 5-APB label "5-APB".
- 5-APB sameAs m.0gh6_46.
- 5-APB sameAs Q4639569.
- 5-APB sameAs Q4639569.
- 5-APB wasDerivedFrom 5-APB?oldid=603272519.
- 5-APB depiction 5-APB2DACS.svg.
- 5-APB isPrimaryTopicOf 5-APB.