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- AEBSF abstract "AEBSF or 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride is a water soluble, irreversible serine protease inhibitor with a molecular weight of 239.5 Da. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, nevertheless AEBSF is more stable at low pH values. Typical usage is 0.1 - 1.0 mM.AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins (SREBP). By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.".
- AEBSF iupacName "4-(2-Aminoethyl)benzenesulfonyl fluoride".
- AEBSF thumbnail AEBSF.png?width=300.
- AEBSF wikiPageExternalLink smi_summary?mid=J00091.
- AEBSF wikiPageExternalLink 78308?brSort=auth&expand=all&listName=abrf&urlStr=.
- AEBSF wikiPageID "5068118".
- AEBSF wikiPageRevisionID "597272950".
- AEBSF hasPhotoCollection AEBSF.
- AEBSF imagealt "AEBSF molecule".
- AEBSF imagefile "AEBSF-3D-balls.png".
- AEBSF imagefile "AEBSF.png".
- AEBSF iupacname "4".
- AEBSF othernames "Pefabloc SC".
- AEBSF verifiedfields "changed".
- AEBSF verifiedrevid "477235294".
- AEBSF subject Category:Phenethylamines.
- AEBSF subject Category:Serine_protease_inhibitors.
- AEBSF subject Category:Sulfonyl_halides.
- AEBSF type Abstraction100002137.
- AEBSF type Chemical114806838.
- AEBSF type Compound114818238.
- AEBSF type Halide114904359.
- AEBSF type Material114580897.
- AEBSF type Matter100020827.
- AEBSF type Part113809207.
- AEBSF type PhysicalEntity100001930.
- AEBSF type Relation100031921.
- AEBSF type Salt115010703.
- AEBSF type Substance100019613.
- AEBSF type SulfonylHalides.
- AEBSF type ChemicalCompound.
- AEBSF type ChemicalSubstance.
- AEBSF type ChemicalSubstanceType.
- AEBSF type ChemicalObject.
- AEBSF type Thing.
- AEBSF comment "AEBSF or 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride is a water soluble, irreversible serine protease inhibitor with a molecular weight of 239.5 Da. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, nevertheless AEBSF is more stable at low pH values.".
- AEBSF label "AEBSF".
- AEBSF label "AEBSF".
- AEBSF label "Fluorure de 4-(2-aminoéthyl)benzènesulfonyle".
- AEBSF label "フッ化 4-(2-アミノエチル)ベンゼンスルホニル".
- AEBSF sameAs AEBSF.
- AEBSF sameAs Fluorure_de_4-(2-aminoéthyl)benzènesulfonyle.
- AEBSF sameAs フッ化_4-(2-アミノエチル)ベンゼンスルホニル.
- AEBSF sameAs m.0d18cr.
- AEBSF sameAs Q290992.
- AEBSF sameAs Q290992.
- AEBSF sameAs AEBSF.
- AEBSF wasDerivedFrom AEBSF?oldid=597272950.
- AEBSF depiction AEBSF.png.
- AEBSF isPrimaryTopicOf AEBSF.