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- ATP-dependent_Clp_protease_adaptor_protein_ClpS abstract "ClpS is an N-recognin in the N-end rule pathway. ClpS interacts with protein substrates that have a bulky hydrophobic residue (leucine, phenylalanine, tyrosine, and tryptophan) at the N-temrinus. The protein substrate is then degraded by the ClpAP protease. In molecular biology, the ATP-dependent Clp protease adaptor protein ClpS is a bacterial protein. In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. ClpS directly influences the ClpAP machine by binding to the N-terminal domain of the chaperone ClpA. The degradation of ClpAP substrates, both SsrA-tagged proteins and ClpA itself, is specifically inhibited by ClpS. ClpS modifies ClpA substrate specificity, potentially redirecting degradation by ClpAP toward aggregated proteins.ClpS is a small alpha/beta protein that consists of three alpha-helices connected to three antiparallel beta-strands. The protein has a globular shape, with a curved layer of three antiparallel alpha-helices over a twisted antiparallel beta-sheet. Dimerization of ClpS may occur through its N-terminal domain. This short extended N-terminal region in ClpS is followed by the central seven-residue beta-strand, which is flanked by two other beta-strands in a small beta-sheet.".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS symbol "ClpS".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS thumbnail PDB_1r6q_EBI.jpg?width=300.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS wikiPageID "32271840".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS wikiPageRevisionID "606365471".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS caption "clpns with fragments".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS hasPhotoCollection ATP-dependent_Clp_protease_adaptor_protein_ClpS.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS interpro "IPR003769".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS name "ClpS".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS pfam "PF02617".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS scop "1".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS symbol "ClpS".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS subject Category:Protein_families.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Abstraction100002137.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Family108078020.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Group100031264.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Organization108008335.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type ProteinFamilies.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type SocialGroup107950920.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Unit108189659.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type YagoLegalActor.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type YagoLegalActorGeo.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type YagoPermanentlyLocatedEntity.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Biomolecule.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type Protein.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS type BiologicalObject.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS comment "ClpS is an N-recognin in the N-end rule pathway. ClpS interacts with protein substrates that have a bulky hydrophobic residue (leucine, phenylalanine, tyrosine, and tryptophan) at the N-temrinus. The protein substrate is then degraded by the ClpAP protease. In molecular biology, the ATP-dependent Clp protease adaptor protein ClpS is a bacterial protein. In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP.".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS label "ATP-dependent Clp protease adaptor protein ClpS".
- ATP-dependent_Clp_protease_adaptor_protein_ClpS sameAs m.0gy1sz7.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS sameAs Q4654790.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS sameAs Q4654790.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS sameAs ATP-dependent_Clp_protease_adaptor_protein_ClpS.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS wasDerivedFrom ATP-dependent_Clp_protease_adaptor_protein_ClpS?oldid=606365471.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS depiction PDB_1r6q_EBI.jpg.
- ATP-dependent_Clp_protease_adaptor_protein_ClpS isPrimaryTopicOf ATP-dependent_Clp_protease_adaptor_protein_ClpS.