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- Autoreceptor abstract "An autoreceptor is a receptor located in presynaptic nerve cell membranes which serves as a part of a negative feedback loop in signal transduction. It is sensitive only to those neurotransmitters or hormones that are released by the neuron in whose membrane the autoreceptor sits. Similarly, a heteroreceptor is one that is sensitive to neurotransmitters and hormones that are not released by the cell in whose membrane it is embedded. Thus a given receptor can act as either an autoreceptor or a heteroreceptor, depending upon the type of transmitter released by the cell in whose membrane it is embedded.Autoreceptors may be located in any part of the cell membrane: in the dendrites, the cell body, the axon, or the axon terminals.Canonically, a presynaptic neuron releases neurotransmitter across a synaptic cleft to be detected by the receptors on a postsynaptic neuron. Autoreceptors on the presynaptic neuron will also detect this neurotransmitter and often function to control internal cell processes, typically inhibiting further release or synthesis of the neurotransmitter. Thus, release of neurotransmitter is regulated by negative feedback. Autoreceptors are usually G protein-coupled receptors (rather than transmitter-gated ion channels) and act via a second messenger.".
- Autoreceptor thumbnail Autorezeptor.png?width=300.
- Autoreceptor wikiPageID "2420212".
- Autoreceptor wikiPageRevisionID "603813864".
- Autoreceptor align "center".
- Autoreceptor alt "A pharmacodynamic model of amphetamine and TAAR1".
- Autoreceptor alt "Autoreceptor diagram".
- Autoreceptor caption "Amphetamine, trace amines, and dopamine can activate in dopamine neurons,but only dopamine activates . These receptors have opposite effects on protein kinase signaling. This results in opposite effects on phosporylation, and consequently, on reuptake as well.".
- Autoreceptor caption "This diagram shows pre-synaptic neuron releasing a neurotransmitter, noradrenaline , into the synaptic cleft. The transmitter acts on the receptors of the post-synaptic neuron , but also on autoreceptors of the pre-synaptic neuron. Activation of these autoreceptors typically inhibits further release of the neurotransmitter.".
- Autoreceptor direction "horizontal".
- Autoreceptor hasPhotoCollection Autoreceptor.
- Autoreceptor image "Autorezeptor.png".
- Autoreceptor image "TAAR1 Dopamine.svg".
- Autoreceptor width "300".
- Autoreceptor width "400".
- Autoreceptor subject Category:Cell_signaling.
- Autoreceptor subject Category:Receptors.
- Autoreceptor subject Category:Signal_transduction.
- Autoreceptor type BodyPart105220461.
- Autoreceptor type Part109385911.
- Autoreceptor type PhysicalEntity100001930.
- Autoreceptor type Receptor105608868.
- Autoreceptor type Receptors.
- Autoreceptor type Structure105225602.
- Autoreceptor type Thing100002452.
- Autoreceptor comment "An autoreceptor is a receptor located in presynaptic nerve cell membranes which serves as a part of a negative feedback loop in signal transduction. It is sensitive only to those neurotransmitters or hormones that are released by the neuron in whose membrane the autoreceptor sits. Similarly, a heteroreceptor is one that is sensitive to neurotransmitters and hormones that are not released by the cell in whose membrane it is embedded.".
- Autoreceptor label "Autoreceptor".
- Autoreceptor label "Autorezeptoren".
- Autoreceptor label "Autorécepteur".
- Autoreceptor sameAs Autorezeptoren.
- Autoreceptor sameAs Autorécepteur.
- Autoreceptor sameAs m.07btrj.
- Autoreceptor sameAs Q417749.
- Autoreceptor sameAs Q417749.
- Autoreceptor sameAs Autoreceptor.
- Autoreceptor wasDerivedFrom Autoreceptor?oldid=603813864.
- Autoreceptor depiction Autorezeptor.png.
- Autoreceptor isPrimaryTopicOf Autoreceptor.