Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Bumetanide> ?p ?o. }
Showing items 1 to 98 of
98
with 100 items per page.
- Bumetanide abstract "Bumetanide (trade names Bumex or Burinex) is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective. It is marketed by Hoffmann-La Roche. The main difference between the two substances is in bioavailability and pharmacodynamic potency. Furosemide is incompletely absorbed in the intestine (60%), and there is substantial inter- and intraindividual differences in bioavailability (range 10-90%). Bumetanide is almost completely absorbed (80%), and the absorption is not altered when it is taken with food. It is said to be a more predictable diuretic, meaning that the predictable absorption is reflected in a more predictable effect.Bumetanide is 40 times more potent than furosemide (for patients with normal renal function).In the brain, bumetanide blocks the NKCC1 cation-chloride co-transporter, and thus decreases internal chloride concentration in neurons. In turn, this concentration change makes the action of GABA more hyperpolarizing, which may be useful for treatment of neonatal seizures, that quite often are not responsive to traditional GABA-targeted treatment, such as barbiturates. Bumetanide is therefore currently under evaluation as a prospective antiepileptic drug.".
- Bumetanide atcPrefix "C03".
- Bumetanide atcSuffix "CA02".
- Bumetanide casNumber "28395-03-1".
- Bumetanide chEBI "3213".
- Bumetanide drugbank "DB00887".
- Bumetanide fdaUniiCode "0Y2S3XUQ5H".
- Bumetanide iupacName "3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid".
- Bumetanide pubchem "2471".
- Bumetanide thumbnail Bumetanide_structure.svg?width=300.
- Bumetanide wikiPageExternalLink 018225s024lbl.pdf.
- Bumetanide wikiPageExternalLink bumetanide.
- Bumetanide wikiPageID "973959".
- Bumetanide wikiPageRevisionID "598550247".
- Bumetanide atcPrefix "3.0".
- Bumetanide atcSuffix "CA02".
- Bumetanide bioavailability "almost complete".
- Bumetanide c "17".
- Bumetanide casNumber "28395".
- Bumetanide chebi "3213".
- Bumetanide chembl "1072".
- Bumetanide chemspiderid "2377".
- Bumetanide drugbank "DB00887".
- Bumetanide eliminationHalfLife "2880.0".
- Bumetanide excretion "renal".
- Bumetanide h "20".
- Bumetanide hasPhotoCollection Bumetanide.
- Bumetanide image "Bumetanide_ball-and-stick.png".
- Bumetanide inchi "1".
- Bumetanide inchikey "MAEIEVLCKWDQJH-UHFFFAOYAE".
- Bumetanide iupacName "3".
- Bumetanide kegg "D00247".
- Bumetanide legalAu "S4".
- Bumetanide legalUk "POM".
- Bumetanide legalUs "Rx-only".
- Bumetanide medlineplus "a684051".
- Bumetanide metabolism "hepatic".
- Bumetanide molecularWeight "364.417".
- Bumetanide n "2".
- Bumetanide o "5".
- Bumetanide pregnancyAu "B3".
- Bumetanide pregnancyUs "C".
- Bumetanide proteinBound "97.0".
- Bumetanide pubchem "2471".
- Bumetanide routesOfAdministration "oral".
- Bumetanide s "1".
- Bumetanide smiles "O=SN".
- Bumetanide stdinchi "1".
- Bumetanide stdinchikey "MAEIEVLCKWDQJH-UHFFFAOYSA-N".
- Bumetanide tradename "Bumex".
- Bumetanide unii "0".
- Bumetanide verifiedrevid "459985487".
- Bumetanide width "200".
- Bumetanide subject Category:Benzoic_acids.
- Bumetanide subject Category:Loop_diuretics.
- Bumetanide subject Category:Phenol_ethers.
- Bumetanide type Abstraction100002137.
- Bumetanide type Acid114607521.
- Bumetanide type BenzoicAcid114775321.
- Bumetanide type BenzoicAcids.
- Bumetanide type CarboxylicAcid114739360.
- Bumetanide type Chemical114806838.
- Bumetanide type Compound114818238.
- Bumetanide type Element114840755.
- Bumetanide type Material114580897.
- Bumetanide type Matter100020827.
- Bumetanide type Part113809207.
- Bumetanide type PhenolEthers.
- Bumetanide type PhysicalEntity100001930.
- Bumetanide type Quintessence114847103.
- Bumetanide type Relation100031921.
- Bumetanide type Substance100019613.
- Bumetanide type Drug.
- Bumetanide type DrugProduct.
- Bumetanide type FunctionalSubstance.
- Bumetanide comment "Bumetanide (trade names Bumex or Burinex) is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective. It is marketed by Hoffmann-La Roche. The main difference between the two substances is in bioavailability and pharmacodynamic potency. Furosemide is incompletely absorbed in the intestine (60%), and there is substantial inter- and intraindividual differences in bioavailability (range 10-90%).".
- Bumetanide label "Bumetanid".
- Bumetanide label "Bumetanida".
- Bumetanide label "Bumetanida".
- Bumetanide label "Bumetanide".
- Bumetanide label "Bumetanide".
- Bumetanide label "Bumétanide".
- Bumetanide label "بوميتانيد".
- Bumetanide sameAs Bumetanid.
- Bumetanide sameAs Bumetanida.
- Bumetanide sameAs Bumétanide.
- Bumetanide sameAs Bumetanide.
- Bumetanide sameAs Bumetanida.
- Bumetanide sameAs m.03vrlp.
- Bumetanide sameAs Q275926.
- Bumetanide sameAs Q275926.
- Bumetanide sameAs bumetanide.
- Bumetanide sameAs DB00887.
- Bumetanide sameAs 2471.
- Bumetanide sameAs Bumetanide.
- Bumetanide wasDerivedFrom Bumetanide?oldid=598550247.
- Bumetanide depiction Bumetanide_structure.svg.
- Bumetanide isPrimaryTopicOf Bumetanide.