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- CGS-15943 abstract "CGS-15943 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A, having a Ki of 3.3nM at A2A and 21nM at A1. It was one of the first adenosine receptor antagonists discovered that is not a xanthine derivative, instead being a triazoloquinazoline. Consequently CGS-15943 has the advantage over most xanthine derivatives that it is not a phosphodiesterase inhibitor, and so has more a specific pharmacological effects profile. It produces similar effects to caffeine in animal studies, though with higher potency.".
- CGS-15943 atcPrefix "none".
- CGS-15943 casNumber "104615-18-1".
- CGS-15943 iupacName "9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine".
- CGS-15943 pubchem "2690".
- CGS-15943 thumbnail CGS-15943_structure.png?width=300.
- CGS-15943 wikiPageID "30055468".
- CGS-15943 wikiPageRevisionID "590888954".
- CGS-15943 atcPrefix "none".
- CGS-15943 c "13".
- CGS-15943 casNumber "104615".
- CGS-15943 chembl "16687".
- CGS-15943 chemspiderid "2589".
- CGS-15943 cl "1".
- CGS-15943 h "8".
- CGS-15943 hasPhotoCollection CGS-15943.
- CGS-15943 iupacName "9".
- CGS-15943 legalStatus "Uncontrolled".
- CGS-15943 molecularWeight "285.689".
- CGS-15943 n "5".
- CGS-15943 o "1".
- CGS-15943 pubchem "2690".
- CGS-15943 smiles "ClC1=CC=C2N=CN3N=CN=C3C2=C1".
- CGS-15943 stdinchi "1".
- CGS-15943 stdinchikey "MSJODEOZODDVGW-UHFFFAOYSA-N".
- CGS-15943 verifiedfields "changed".
- CGS-15943 verifiedrevid "459989149".
- CGS-15943 watchedfields "changed".
- CGS-15943 subject Category:Adenosine_antagonists.
- CGS-15943 type Drug.
- CGS-15943 type FunctionalSubstance.
- CGS-15943 comment "CGS-15943 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A, having a Ki of 3.3nM at A2A and 21nM at A1. It was one of the first adenosine receptor antagonists discovered that is not a xanthine derivative, instead being a triazoloquinazoline. Consequently CGS-15943 has the advantage over most xanthine derivatives that it is not a phosphodiesterase inhibitor, and so has more a specific pharmacological effects profile.".
- CGS-15943 label "CGS-15943".
- CGS-15943 sameAs m.0g5b0r7.
- CGS-15943 sameAs Q5010994.
- CGS-15943 sameAs Q5010994.
- CGS-15943 wasDerivedFrom CGS-15943?oldid=590888954.
- CGS-15943 depiction CGS-15943_structure.png.
- CGS-15943 isPrimaryTopicOf CGS-15943.