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- Cycloguanil abstract "Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil. However, more recent work has indicated that, while proguanil is synergistic with the drug atovaquone (as in the combination Malarone), cycloguanil is in fact antagonistic to the effects of atovaquone, suggesting that, unlike cycloguanil, proguanil may have an alternative mechanism of antimalarial action besides dihydrofolate reductase inhibition.Although cycloguanil is not currently in general use as an antimalarial, the continuing development of resistance to current antimalarial drugs has led to renewed interest in studying the use of cycloguanil in combination with other drugs.".
- Cycloguanil atcPrefix "P01".
- Cycloguanil atcSuffix "BB02".
- Cycloguanil casNumber "516-21-2".
- Cycloguanil fdaUniiCode "26RM326WVN".
- Cycloguanil iupacName "1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine".
- Cycloguanil pubchem "9049".
- Cycloguanil thumbnail Cycloguanil.svg?width=300.
- Cycloguanil wikiPageID "12573921".
- Cycloguanil wikiPageRevisionID "593927862".
- Cycloguanil atcPrefix "P01".
- Cycloguanil atcSuffix "BB02".
- Cycloguanil c "11".
- Cycloguanil casNumber "516".
- Cycloguanil chembl "747".
- Cycloguanil chemspiderid "8697".
- Cycloguanil cl "1".
- Cycloguanil h "14".
- Cycloguanil hasPhotoCollection Cycloguanil.
- Cycloguanil image "cycloguanil_sf.png".
- Cycloguanil inchi "1".
- Cycloguanil inchikey "QMNFFXRFOJIOKZ-UHFFFAOYAH".
- Cycloguanil iupacName "1".
- Cycloguanil molecularWeight "251.715".
- Cycloguanil n "5".
- Cycloguanil pubchem "9049".
- Cycloguanil smiles "Clc1cccN2C\N".
- Cycloguanil stdinchi "1".
- Cycloguanil stdinchikey "QMNFFXRFOJIOKZ-UHFFFAOYSA-N".
- Cycloguanil unii "26".
- Cycloguanil verifiedrevid "443546900".
- Cycloguanil watchedfields "changed".
- Cycloguanil subject Category:Antimalarial_agents.
- Cycloguanil subject Category:Guanidines.
- Cycloguanil subject Category:Organochlorides.
- Cycloguanil subject Category:Triazines.
- Cycloguanil type Abstraction100002137.
- Cycloguanil type Chemical114806838.
- Cycloguanil type Compound114818238.
- Cycloguanil type Material114580897.
- Cycloguanil type Matter100020827.
- Cycloguanil type Part113809207.
- Cycloguanil type PhysicalEntity100001930.
- Cycloguanil type Relation100031921.
- Cycloguanil type Substance100019613.
- Cycloguanil type Triazine115079030.
- Cycloguanil type Triazines.
- Cycloguanil type Drug.
- Cycloguanil type DrugProduct.
- Cycloguanil type FunctionalSubstance.
- Cycloguanil comment "Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil.".
- Cycloguanil label "Cycloguanil".
- Cycloguanil sameAs m.02wwdtf.
- Cycloguanil sameAs Q5198706.
- Cycloguanil sameAs Q5198706.
- Cycloguanil sameAs Cycloguanil.
- Cycloguanil wasDerivedFrom Cycloguanil?oldid=593927862.
- Cycloguanil depiction Cycloguanil.svg.
- Cycloguanil isPrimaryTopicOf Cycloguanil.