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- Double_minute abstract "Double minutes are small fragments of extrachromosomal DNA, which have been observed in a large number of human tumors including breast, lung, ovary, colon, and most notably, neuroblastoma. They are a manifestation of gene amplification during the development of tumors, which give the cells selective advantages for growth and survival. They frequently harbor amplified oncogenes and genes involved in drug resistance. Double minutes, like actual chromosomes, are composed of chromatin and replicate in the nucleus of the cell during cell division. Unlike typical chromosomes, they are composed of circular fragments of DNA, up to only a few million base pairs in size and contain no centromere or telomere.".
- Double_minute wikiPageExternalLink 0165-4608(82)90043-7.
- Double_minute wikiPageID "2153773".
- Double_minute wikiPageRevisionID "591056461".
- Double_minute hasPhotoCollection Double_minute.
- Double_minute subject Category:DNA.
- Double_minute subject Category:Medical_genetics.
- Double_minute subject Category:Oncology.
- Double_minute comment "Double minutes are small fragments of extrachromosomal DNA, which have been observed in a large number of human tumors including breast, lung, ovary, colon, and most notably, neuroblastoma. They are a manifestation of gene amplification during the development of tumors, which give the cells selective advantages for growth and survival. They frequently harbor amplified oncogenes and genes involved in drug resistance.".
- Double_minute label "Double minute".
- Double_minute label "Double minute".
- Double_minute label "二重微小染色体".
- Double_minute sameAs Double_minute.
- Double_minute sameAs 二重微小染色体.
- Double_minute sameAs m.06qrfz.
- Double_minute sameAs Q410163.
- Double_minute sameAs Q410163.
- Double_minute wasDerivedFrom Double_minute?oldid=591056461.
- Double_minute isPrimaryTopicOf Double_minute.