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- MiR-296 abstract "miR-296 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference.miR-296 has been named an "angiomiR" due to being characterised as a microRNA which regulates angiogenesis, the process of growth and creation of new blood vessels. miR-296 is thought to have a specific role in cancer in promoting tumour angiogenesis. It achieves this by targeting HGS mRNA, reducing its expression in endothelial cells which then results in greater number of VEGF receptors.miR-296 has predicted target sites in the transcription factor NANOG and may also contribute to carcinogenesis by dysregulating p53.".
- MiR-296 thumbnail Mir-296_SS.png?width=300.
- MiR-296 wikiPageID "33060763".
- MiR-296 wikiPageRevisionID "587889389".
- MiR-296 altsymbols "MIR296".
- MiR-296 arm "q".
- MiR-296 band "13.32".
- MiR-296 caption "Conserved secondary structure of miR-296 microRNA precursor".
- MiR-296 chromosome "20".
- MiR-296 entrezgene "407022".
- MiR-296 go "35195".
- MiR-296 hasPhotoCollection MiR-296.
- MiR-296 hgncid "31617".
- MiR-296 id "RF00733".
- MiR-296 mirbase "MI0000747".
- MiR-296 mirbaseFamily "MIPF0000159".
- MiR-296 name "miR-296".
- MiR-296 name "microRNA mir-296".
- MiR-296 omim "610945".
- MiR-296 refseq "NR_029844".
- MiR-296 rfam "RF00733".
- MiR-296 rnaType "miRNA".
- MiR-296 so "1244".
- MiR-296 symbol "miR-296".
- MiR-296 taxDomain Mammal.
- MiR-296 subject Category:MicroRNA.
- MiR-296 comment "miR-296 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference.miR-296 has been named an "angiomiR" due to being characterised as a microRNA which regulates angiogenesis, the process of growth and creation of new blood vessels.".
- MiR-296 label "MiR-296".
- MiR-296 sameAs m.0h55x46.
- MiR-296 sameAs Q6826944.
- MiR-296 sameAs Q6826944.
- MiR-296 wasDerivedFrom MiR-296?oldid=587889389.
- MiR-296 depiction Mir-296_SS.png.
- MiR-296 isPrimaryTopicOf MiR-296.