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- Miltefosine abstract "Miltefosine (INN, trade names Impavido and Miltex) is a phospholipid drug. Chemically it is a derivative of alkylphosphocholine compounds discovered in the early 1980s. It was developed in the late 1980s as an anticancer drug by German scientists Hansjörg Eibl and Clemens Unger. Simultaneously but independently it was found that the drug could kill Leishmania parasites, and since the mid-1990s successful clinical trials were conducted. The drug became the first (and still the only prescribed) oral drug in the treatment of leishmaniasis. It is now known to be a broad-spectrum antimicrobial drug, active against pathogenic bacteria and fungi, as well as human trematode Schistosoma mansoni and its vector host, the snail Biomphalaria alexandrina. It can be administered orally and topically.In the target cell, it acts as an Akt inhibitor. Therefore, it is also under investigation as a potential therapy against HIV infection.".
- Miltefosine atcPrefix "L01".
- Miltefosine atcSuffix "XX09".
- Miltefosine casNumber "58066-85-6".
- Miltefosine chEBI "75283".
- Miltefosine fdaUniiCode "53EY29W7EC".
- Miltefosine iupacName "2-(hexadecoxy-oxido-phosphoryl)oxyethyl-trimethyl-azanium".
- Miltefosine pubchem "3599".
- Miltefosine thumbnail Miltefosine.svg?width=300.
- Miltefosine wikiPageExternalLink miltefosine.html.
- Miltefosine wikiPageExternalLink news.php?Dafra%20Pharma%20R%26D%20has%20been%20awarded%20an%20exclusive%20licence%20from%20the%20Max%20Planck%20Society%20to%20develop%20a%20drug%20against%20leishmaniasis&id=365.
- Miltefosine wikiPageExternalLink miltefosine.htm.
- Miltefosine wikiPageExternalLink 812862.
- Miltefosine wikiPageID "6803333".
- Miltefosine wikiPageRevisionID "604815603".
- Miltefosine atcPrefix "L01".
- Miltefosine atcSuffix "XX09".
- Miltefosine bioavailability "High".
- Miltefosine c "21".
- Miltefosine casNumber "58066".
- Miltefosine chebi "75283".
- Miltefosine chembl "125".
- Miltefosine chemspiderid "3473".
- Miltefosine eliminationHalfLife "2678400.0".
- Miltefosine h "46".
- Miltefosine hasPhotoCollection Miltefosine.
- Miltefosine inchi "1".
- Miltefosine inchikey "PQLXHQMOHUQAKB-UHFFFAOYAN".
- Miltefosine iupacName "2".
- Miltefosine kegg "D02494".
- Miltefosine molecularWeight "407.568".
- Miltefosine n "1".
- Miltefosine niaidChemdb "130571".
- Miltefosine o "4".
- Miltefosine p "1".
- Miltefosine pubchem "3599".
- Miltefosine routesOfAdministration "Oral".
- Miltefosine smiles "[O-]POCC[N+]C".
- Miltefosine stdinchi "1".
- Miltefosine stdinchikey "PQLXHQMOHUQAKB-UHFFFAOYSA-N".
- Miltefosine unii "53".
- Miltefosine verifiedfields "changed".
- Miltefosine verifiedrevid "462252576".
- Miltefosine width "300".
- Miltefosine subject Category:Antifungals.
- Miltefosine subject Category:Antineoplastic_drugs.
- Miltefosine subject Category:Antiprotozoal_agents.
- Miltefosine subject Category:Antiretroviral_drugs.
- Miltefosine subject Category:Embryotoxicants.
- Miltefosine subject Category:Fetotoxicants.
- Miltefosine subject Category:Protein_kinase_inhibitors.
- Miltefosine subject Category:Quaternary_ammonium_compounds.
- Miltefosine subject Category:Zwitterions.
- Miltefosine type Agent109190918.
- Miltefosine type Agent114778436.
- Miltefosine type Antifungal102720201.
- Miltefosine type Antifungals.
- Miltefosine type Antineoplastic102722458.
- Miltefosine type AntineoplasticDrugs.
- Miltefosine type AntiprotozoalAgents.
- Miltefosine type AntiretroviralDrugs.
- Miltefosine type CausalAgent100007347.
- Miltefosine type CytotoxicDrug103157987.
- Miltefosine type Drug103247620.
- Miltefosine type Inhibitor114724436.
- Miltefosine type Matter100020827.
- Miltefosine type Medicine103740161.
- Miltefosine type PhysicalEntity100001930.
- Miltefosine type ProteinKinaseInhibitors.
- Miltefosine type Substance100020090.
- Miltefosine type Drug.
- Miltefosine type DrugProduct.
- Miltefosine type FunctionalSubstance.
- Miltefosine comment "Miltefosine (INN, trade names Impavido and Miltex) is a phospholipid drug. Chemically it is a derivative of alkylphosphocholine compounds discovered in the early 1980s. It was developed in the late 1980s as an anticancer drug by German scientists Hansjörg Eibl and Clemens Unger. Simultaneously but independently it was found that the drug could kill Leishmania parasites, and since the mid-1990s successful clinical trials were conducted.".
- Miltefosine label "Miltefosin".
- Miltefosine label "Miltefosina".
- Miltefosine label "Miltefosine".
- Miltefosine label "Miltefosine".
- Miltefosine label "Miltéfosine".
- Miltefosine sameAs Miltefosin.
- Miltefosine sameAs Miltefosina.
- Miltefosine sameAs Miltéfosine.
- Miltefosine sameAs Miltefosine.
- Miltefosine sameAs m.0gpr90.
- Miltefosine sameAs Q411787.
- Miltefosine sameAs Q411787.
- Miltefosine sameAs Miltefosine.
- Miltefosine wasDerivedFrom Miltefosine?oldid=604815603.
- Miltefosine depiction Miltefosine.svg.
- Miltefosine isPrimaryTopicOf Miltefosine.