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- catalog abstract "The articles in this volume represent papers delivered by invited speakers at the 7th International Symposium on the Immunobiology of Proteins and Peptides. In addition, a few of the abstracts submitted by participants were scheduled for minisymposia and some of the authors, whose presentations were judged by the Scientific Council to be of high quality, were invited to submit papers for publication in this volume. This symposium was established in 1976 for the purpose of bring together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings and discuss their significance in the light of current concepts and to identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs will lead to recognition of proteins and peptide. We believed that these breakthroughs will lead to the creation of a new generation of peptide reagents with should have enormous potential in biological, therapeutic, and basic applications. This anticipated explosion has in fact since occurred and many applications of these peptides are now being realized. The seventh symposium focused on immune responses that have undesirable effects on the host, hence we named them unwanted immune responses. Two major aspects of unwanted immune responses were discussed at the symposium: Allergy and Autoimmunity. We believed that these immune reactions may be controlled or manipulated by similar strategies. This volume presents papers on the molecular nature of allergens, IgE-mediated responses and the IgE receptors. The papers on autoimmunity deal with autoimmune antibody and T-cell recognition of self antigens in selected well-characterized autoimmune diseases (e.g., rheumatoid arthritis, myasthenia, gravis, systemic lupus erthematosus and autoimmune, type 1 diabetes). Stress proteins, naturally occurring autoantibodies and regulatory autoantibodies are now known to play important roles in autoimmunity. Papers by leading investigators present recent advances in this field. Manipulation of autoimmune responses by synthetic pathogenic autodeterminants provides promising strategies for control of autoimmune diseases whose antigens have been well characterized. The feasibility of this exciting direction is demonstrated here with autoimmune diseases, but should in principle be applicable to allergic responses as well. These and other important questions related to molecular and cellular characterization of allergic and autoimmune responses are discussed in this volume Finally, I should like to express, on behalf of this organization, out gratitude, our gratitude to our sponsors whose generous support made this conference possible.".
- catalog contributor b6560200.
- catalog contributor b6560201.
- catalog contributor b6560202.
- catalog created "c1994.".
- catalog date "1994".
- catalog date "c1994.".
- catalog dateCopyrighted "c1994.".
- catalog description "Includes bibliographical references and index.".
- catalog description "Is There a Link between the Nature of Agents That Trigger Mast Cells and the Induction of Immunoglobulin (IG)E Synthesis? / Birgit A. Helm -- Immunogenetic Aspects of IgE-Mediated Responses / Shau-Ku Huang, Ming Yi, Megumi Kumai and David G. Marsh -- Structure and Function of the Low Affinity IgE Receptor / Daniel H. Conrad, Kim A. Campbell, William C. Bartlett, Coles M. Squire and Steven E. Dierks -- Characterization of the Human IgE Fc-Fc[epsilon]RI[alpha] Interaction / Jarema P. Kochan, Michael Mallamaci, Alasdair Gilfillan, Vincent Madison and Mitali Basu -- The Analysis of Mast Cell Function in Vivo Using Mast Cell-Deficient Mice / Barry K. Wershil and Stephen J. Galli -- The Immunogenetic Basis of Collagen Induced Arthritis in Mice: An Experimental Model for the Rational Design of Immunomodulatory Treatments of Rheumatoid Arthritis / Gerald H. Nabozny and Chella David.".
- catalog description "Naturally Occurring Human Autoantibodies to Defend T-Cell Receptor and Light Chain Peptides / John J. Marchalonis, Hulya Kaymaz, Samuel F. Schluter and David F. Yocum -- Natural Autoantibodies / Sylvia K. Chai, Liliana Mantovani, Marion T. Kasaian and Paolo Casali -- Regulatory Autoantibody and Cellular Aging and Removal / Marguerite M. B. Kay -- B-Cell Origin of Cold Agglutinins / Leslie E. Silberstein -- Initiation of Autoimmune Type 1 Diabetes and Molecular Cloning of a Gene Encoding for Islet Cell-Specific 37KD Autoantigen / Hee Sook Jun and Ji-Won Yoon -- Mapping of the Polypeptide Chain Organization of the Main Extracellular Domain of the [alpha]-Subunit in Membrane-Bound Acetylcholine Receptor by Anti-Peptide Antibodies Spanning the Entire Domain / M. Zouhair Atassi, Biserka Mulac-Jericevic and Tetsuo Ashizawa.".
- catalog description "Suppression of Experimental Autoimmune Myasthenia Gravis by Epitope-Specific Neonatal Tolerance / Premkumar Christadoss, Mohan Shenoy, Minako Oshima and M. Zouhair Atassi -- T Cell Reactivity to Self and Allogeneic MHC-Peptides / Zhuoru Liu, Paul Harris and Nicole Suciu-Foca -- Antiribosomal Antibodies in SLE, Infection, and Following Deliberate Immunization / Keith B. Elkon, Eloisa Bonfa, Herbert Weissbach and Nathan Brot -- Cross-Reactions of Anti-Immunoglobulin Sera with Synthetic T-Cell Receptor [beta] Peptides: Mapping on a 3-Dimension Model / H. Kaymaz, F. Dedeoglu, S. F. Schluter, A. B. Edmundson and J. M. Marchalonis -- Stress Proteins in Autoimmunity / John Winfield and Wael Jarjour -- Polyclonal B Cell Activation and B Cell Cross-Reactivity During Autoantibody Production in Systemic Lupus Erythematosus / Dennis M. Klinman, Akira Shirai and Yoshiaki Ishigatsubo -- Autoantibody Activity and V Gene Usage by B-Cell Malignancies / Guillaume Dighiero.".
- catalog description "The articles in this volume represent papers delivered by invited speakers at the 7th International Symposium on the Immunobiology of Proteins and Peptides. In addition, a few of the abstracts submitted by participants were scheduled for minisymposia and some of the authors, whose presentations were judged by the Scientific Council to be of high quality, were invited to submit papers for publication in this volume. This symposium was established in 1976 for the purpose of bring together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings and discuss their significance in the light of current concepts and to identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs will lead to recognition of proteins and peptide. ".
- catalog description "The papers on autoimmunity deal with autoimmune antibody and T-cell recognition of self antigens in selected well-characterized autoimmune diseases (e.g., rheumatoid arthritis, myasthenia, gravis, systemic lupus erthematosus and autoimmune, type 1 diabetes). Stress proteins, naturally occurring autoantibodies and regulatory autoantibodies are now known to play important roles in autoimmunity. Papers by leading investigators present recent advances in this field. Manipulation of autoimmune responses by synthetic pathogenic autodeterminants provides promising strategies for control of autoimmune diseases whose antigens have been well characterized. The feasibility of this exciting direction is demonstrated here with autoimmune diseases, but should in principle be applicable to allergic responses as well. ".
- catalog description "These and other important questions related to molecular and cellular characterization of allergic and autoimmune responses are discussed in this volume Finally, I should like to express, on behalf of this organization, out gratitude, our gratitude to our sponsors whose generous support made this conference possible.".
- catalog description "We believed that these breakthroughs will lead to the creation of a new generation of peptide reagents with should have enormous potential in biological, therapeutic, and basic applications. This anticipated explosion has in fact since occurred and many applications of these peptides are now being realized. The seventh symposium focused on immune responses that have undesirable effects on the host, hence we named them unwanted immune responses. Two major aspects of unwanted immune responses were discussed at the symposium: Allergy and Autoimmunity. We believed that these immune reactions may be controlled or manipulated by similar strategies. This volume presents papers on the molecular nature of allergens, IgE-mediated responses and the IgE receptors. ".
- catalog extent "xi, 231 p. :".
- catalog identifier "0306446650".
- catalog isPartOf "Advances in experimental medicine and biology ; v.347".
- catalog issued "1994".
- catalog issued "c1994.".
- catalog language "eng".
- catalog publisher "New York : Plenum Press,".
- catalog subject "616.97 20".
- catalog subject "Allergy Congresses.".
- catalog subject "Allergy and Immunology congresses.".
- catalog subject "Autoimmunity Congresses.".
- catalog subject "Autoimmunity congresses.".
- catalog subject "Hypersensitivity Congresses.".
- catalog subject "Peptides Immunology Congresses.".
- catalog subject "Peptides congresses.".
- catalog subject "Peptides immunology Congresses.".
- catalog subject "Proteins Immunology Congresses.".
- catalog subject "Proteins congresses.".
- catalog subject "Proteins immunology Congresses.".
- catalog subject "QR188.3 .I58 1992".
- catalog subject "QW 504 I3225 1994".
- catalog subject "W1 AD559 v.347 1994".
- catalog tableOfContents "Is There a Link between the Nature of Agents That Trigger Mast Cells and the Induction of Immunoglobulin (IG)E Synthesis? / Birgit A. Helm -- Immunogenetic Aspects of IgE-Mediated Responses / Shau-Ku Huang, Ming Yi, Megumi Kumai and David G. Marsh -- Structure and Function of the Low Affinity IgE Receptor / Daniel H. Conrad, Kim A. Campbell, William C. Bartlett, Coles M. Squire and Steven E. Dierks -- Characterization of the Human IgE Fc-Fc[epsilon]RI[alpha] Interaction / Jarema P. Kochan, Michael Mallamaci, Alasdair Gilfillan, Vincent Madison and Mitali Basu -- The Analysis of Mast Cell Function in Vivo Using Mast Cell-Deficient Mice / Barry K. Wershil and Stephen J. Galli -- The Immunogenetic Basis of Collagen Induced Arthritis in Mice: An Experimental Model for the Rational Design of Immunomodulatory Treatments of Rheumatoid Arthritis / Gerald H. Nabozny and Chella David.".
- catalog tableOfContents "Naturally Occurring Human Autoantibodies to Defend T-Cell Receptor and Light Chain Peptides / John J. Marchalonis, Hulya Kaymaz, Samuel F. Schluter and David F. Yocum -- Natural Autoantibodies / Sylvia K. Chai, Liliana Mantovani, Marion T. Kasaian and Paolo Casali -- Regulatory Autoantibody and Cellular Aging and Removal / Marguerite M. B. Kay -- B-Cell Origin of Cold Agglutinins / Leslie E. Silberstein -- Initiation of Autoimmune Type 1 Diabetes and Molecular Cloning of a Gene Encoding for Islet Cell-Specific 37KD Autoantigen / Hee Sook Jun and Ji-Won Yoon -- Mapping of the Polypeptide Chain Organization of the Main Extracellular Domain of the [alpha]-Subunit in Membrane-Bound Acetylcholine Receptor by Anti-Peptide Antibodies Spanning the Entire Domain / M. Zouhair Atassi, Biserka Mulac-Jericevic and Tetsuo Ashizawa.".
- catalog tableOfContents "Suppression of Experimental Autoimmune Myasthenia Gravis by Epitope-Specific Neonatal Tolerance / Premkumar Christadoss, Mohan Shenoy, Minako Oshima and M. Zouhair Atassi -- T Cell Reactivity to Self and Allogeneic MHC-Peptides / Zhuoru Liu, Paul Harris and Nicole Suciu-Foca -- Antiribosomal Antibodies in SLE, Infection, and Following Deliberate Immunization / Keith B. Elkon, Eloisa Bonfa, Herbert Weissbach and Nathan Brot -- Cross-Reactions of Anti-Immunoglobulin Sera with Synthetic T-Cell Receptor [beta] Peptides: Mapping on a 3-Dimension Model / H. Kaymaz, F. Dedeoglu, S. F. Schluter, A. B. Edmundson and J. M. Marchalonis -- Stress Proteins in Autoimmunity / John Winfield and Wael Jarjour -- Polyclonal B Cell Activation and B Cell Cross-Reactivity During Autoantibody Production in Systemic Lupus Erythematosus / Dennis M. Klinman, Akira Shirai and Yoshiaki Ishigatsubo -- Autoantibody Activity and V Gene Usage by B-Cell Malignancies / Guillaume Dighiero.".
- catalog title "Immunobiology of proteins and peptides VII : unwanted immune responses / edited by M. Zouhair Atassi.".
- catalog type "Conference proceedings. fast".
- catalog type "text".