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- 2009388560 abstract "This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description.".
- 2009388560 contributor B11559132.
- 2009388560 created "c2008.".
- 2009388560 date "2008".
- 2009388560 date "c2008.".
- 2009388560 dateCopyrighted "c2008.".
- 2009388560 description "Includes bibliographical references.".
- 2009388560 description "Skin sensitization in chemical risk assessment : report of a WHO/IPCS international workshop focusing on dose-response assessment / H. Van Loveren, ... [et al.].".
- 2009388560 description "This publication presents the conclusions of an IPCS Workshop on Skin Sensitization in Chemical Risk Assessment. The workshop focused on the question of methods for dose-response assessment, to evaluate the relative ability of a chemical to induce sensitization in the skin, and hence inform risk assessment for humans. In addition this publication includes a series of short articles on this topic by leading experts in the field. The conclusions of the workshop cover such aspects as the nature and utility for risk assessment of the data produced by non-animal test methods (such as quantitative structure-activity relationships), in vitro testing approaches, animal test methods, and epidemiological studies. While traditional animal test methods used for identification and regulation of skin sensitizers have focused on determining whether or not a substance is a sensitizer, this report describes the use of tests for deriving more informative potency information.--Publisher's description.".
- 2009388560 extent "iv, 85 p. :".
- 2009388560 hasFormat "Also available online.".
- 2009388560 identifier "9241563605".
- 2009388560 identifier "9789241563604".
- 2009388560 identifier 9789241563604_eng.pdf.
- 2009388560 isFormatOf "Also available online.".
- 2009388560 isPartOf "Harmonization Project document ; no. 5".
- 2009388560 isPartOf "Harmonization Project document ; no. 5.".
- 2009388560 issued "2008".
- 2009388560 issued "c2008.".
- 2009388560 language "eng".
- 2009388560 publisher "Geneva, Switzerland : World Health Organization,".
- 2009388560 relation "Also available online.".
- 2009388560 subject "Alergia e imunologia. larpcal".
- 2009388560 subject "Chemicals Physiological effect.".
- 2009388560 subject "Dermatite. larpcal".
- 2009388560 subject "Dermatitis, Contact physiopathology.".
- 2009388560 subject "Hazardous Substances toxicity.".
- 2009388560 subject "Hazardous substances Risk assessment.".
- 2009388560 subject "Health risk assessment.".
- 2009388560 subject "Risk Assessment methods.".
- 2009388560 subject "Skin Tests methods.".
- 2009388560 subject "Skin tests.".
- 2009388560 subject "TD196.C45 S56 2008".
- 2009388560 subject "Toxicology.".
- 2009388560 tableOfContents "Skin sensitization in chemical risk assessment : report of a WHO/IPCS international workshop focusing on dose-response assessment / H. Van Loveren, ... [et al.].".
- 2009388560 title "Skin sensitization in chemical risk assessment.".
- 2009388560 type "text".