Matches in Ghent University Academic Bibliography for { ?s <http://schema.org/abstract> ?o. }
- 01GMWG4YT17APMD0TZXPJNC1EB abstract "The presence and zoonotic transfer of four different avian Chlamydia spp. was assessed in an epidemiological study in a psittacine bird population and its owners. Fecal swabs from 84 pet birds and pharyngeal swabs from 22 bird owners were collected from 21 locations in Flanders. Samples were examined using established and novel PCR platforms combined with culture on PCR-positive samples. Chlamydiaceae DNA was detected in 33 of 84 (39.3%) birds. The predominant part of the avian infections could be attributed to C. psittaci (22 of 84; 26.2%), followed by C. avium (11 of 84; 13.1%). C. gallinacea and C. abortus were not detected in birds or humans. C. psittaci was the only species detected in pet bird owners (4 of 22; 18.2%), stressing its zoonotic importance. This study showed that C. psittaci and the more recently discovered novel avian species C. avium are undoubtedly present in the Flemish psittacine bird population. Our results justify additional research in a larger psittacine bird population and its owners, focusing on C. psittaci and C. avium. In the meantime, increased awareness among pet bird owners and the implementation of preventive measures in the pet bird industry is advised to limit the circulation of established and novel emerging avian chlamydial species.".
- 01GMWG53PR7W5XW3T4QZX73689 abstract "Many phage genes lack sequence similarity to any other open reading frame (ORF) in current databases. These enigmatic ORFan genes can have a tremendous impact on phage propagation and host interactions but often remain experimentally unexplored. We previously revealed a novel interaction between phage P22 and its Salmonella Typhimurium host, instigated by the ORFan gene pid (for phage P22 encoded instigator of dgo expression) and resulting in derepression of the host dgoRKAT operon. The pid gene is highly expressed in phage carrier cells that harbor a polarly located P22 episome that segregates asymmetrically among daughter cells. Here, we discovered that the pid locus is fitted with a weak promoter, has an exceptionally long 5 ' untranslated region that is instructive for a secondary pid mRNA species, and has a 3 ' Rho-independent termination loop that is responsible for stability of the pid transcript.".
- 01GMWG8N0T9HTZY3DQEFC27D29 abstract "Longitudinal mechanical ventilation systems are widely employed to prevent smoke back-layering in tunnel fires. Correlations for the critical velocity of ventilation in tunnels have already been extensively studied, for given fire and tunnel (cross-sectional) dimensions. This work describes the potential of a novel concept of an automatic ventilation system based on a PID (Proportional-Integral-Derivative) controller for preventing smoke back-layering under a priori unknown fire size. A few different tunnel dimensions and heat release rates (HRR) are addressed in order to illustrate how the ventilation velocity adapts automatically. Two methods to identify the location of the smoke front are proposed, based on temperature information. Simulation results show that the proposed approach can control the smoke well, preventing back-layering in real-time. It has excellent adapt-ability for the unknown fire size, which is considered an advantage compared to a system based on constant ventilation velocity. The smoke front becomes stable more quickly for higher HRR, while it takes longer to stabilize for increased tunnel height. This relates to the flame height: sufficiently high flames (compared to the tunnel height) induce a fast rise in temperature, which is the input parameter for the PID system. The tunnel width therefore has little impact. The values for the critical velocity and for the ventilation velocity at maximum smoke back-layering length (BL), as obtained with the proposed method, agree well with existing correlations. The influence of the set-point value for temperature is briefly discussed.".
- 01GMWH4KQEK2CPCHMY3YTGP145 abstract "About 700 scientists from 45 countries gathered in Dresden for the first time since the start of the COVID-19 pandemic to share their latest findings on metal-organic frameworks and open frameworks compounds.".
- 01GMWKB1WZEP2HBJCNJSQRKEFB abstract "Airborne wind energy (AWE) is an emerging technology for the conversion of wind energy into electricity by flying crosswind patterns with a tethered aircraft connected to a generator either on board or on the ground. Having a proper understanding of the unsteady interaction of the air with the flexible and dynamic system during operation is key to developing viable AWE systems. The research goal is to simulate the time-varying fluid-structure interaction (FSI) of an AWE system in a crosswind flight maneuver using high fidelity simulation tools. In this work a framework is presented that serves as a proof of concept to perform high fidelity simulations of airborne wind energy systems. This is done using a partitioned and explicit approach in the open-source coupling tool CoCoNuT. An existing finite element method (FEM) model of the wing structure is coupled with a newly developed computational fluid dynamics (CFD) model of the wing aerodynamics including rigid body motion. It has been found that the mesh deformation is quite sensitive to dynamic mesh parameters. On the other hand, the overset/Chimera technique has been proven to be a robust approach to simulate the motion of an AWE system in CFD simulations.".
- 01GMWKTPSMQ9RT9ECT0DG9JBRF abstract "Airborne wind energy (AWE) is an emerging technology for the conversion of wind energy into electricity by flying crosswind patterns with a tethered aircraft. Having a proper understanding of the unsteady interaction of the air with the highly dynamic system during operation is key to developing viable AWE systems. High fidelity simulation tools are needed to correctly predict these interactions, which will provide insights into the design and operation of advanced and efficient AWE systems. The research goal of this contribution is to predict the time-varying aerodynamic forces acting on a reference system, which will be achieved using high-fidelity modelling. This work contains a feasibility study that uses the Chimera overset technique to simulate aerodynamic behaviour over the complete flight trajectory. The motion of the AWE system is included by overlaying the moving body-fitted mesh attached to the AWE aircraft over the background mesh. The Chimera overset technique connects both meshes, interpolating the solution at the overset boundary. This technique has been proven to be a robust approach to simulate the motion of an AWE system in computational fluid dynamics (CFD) simulations.".
- 01GMWKY4KFSRTJKVHB41BYD7SE abstract "A recent trend observed in the Kubernetes world is trying to deploy a Kubernetes cluster entirely or partially to the edge. When further looking into these edge environments, it is often noted that wireless technologies are used. Kubernetes is not designed to support these wireless network setups and will have to be extended to run smoothly on these networks. One of the most used network setups in edge environments is a wireless mesh network. Therefore the main focus will be on running Kubernetes on top of a wireless mesh network. Other mesh networks will also be supported with a minimal set of changes needed. The main goal of this paper is to list all the problems encountered when running Kubernetes on top of a mesh network and provide a framework of components and extensions to solve these problems. The majority of these components will be implemented, and demonstrations show that these components are able to solve most of the listed problems when used in a setup with some predefined restrictions. When deploying a demo application with the proposed solution, the required bitrate is observed 97 percent of the time compared to 42 percent with the native Kubernetes scheduler.".
- 01GMWQP0G2MHFTBTBXVJW0XQY8 abstract "Binding affinity prediction by means of computer simulation has been increasingly incorporated in drug discovery projects. Its wide application, however, is limited by the prediction accuracy of the free energy calculations. The main error sources are force fields used to describe molecular interactions and incomplete sampling of the configurational space. Organic host-guest systems have been used to address force field quality because they share similar interactions found in ligands and receptors, and their rigidity facilitates configurational sampling. Here, we test the binding free energy prediction accuracy for 14 guests with an aromatic or adamantane core and the CB7 host using molecular electron density derived nonbonded force field parameters. We developed a computational workflow written in Python to derive atomic charges and Lennard-Jones parameters with the Minimal Basis Iterative Stockholder method using the polarized electron density of several configurations of each guest in the bound and unbound states. The resulting nonbonded force field parameters improve binding affinity prediction, especially for guests with an adamantane core in which repulsive exchange and dispersion interactions to the host dominate.".
- 01GMWR128RAV5ZCHMW9KN4ZX4E abstract "Studenten Nederlands die druk aan een paper werkten, scholieren in het middelbaar onderwijs die hun mondeling over de literatuurlijst voorbereidden, journalisten die in allerijl een portret over een schrijver moesten maken, docenten, uitgevers – allemaal hebben ze in het verleden hun toevlucht gezocht bij het Kritisch Literatuur Lexicon, de serie bruine banden met de rugtitel in helder geel die je in vrijwel iedere bibliotheek in Nederland kon vinden. In die banden bevond zich een losbladig naslagwerk waarin over talloze bekende en minder bekende auteurs een toegankelijk geschreven maar met de belangrijkste wetenschappelijke inzichten gevoed overzichtsartikel te vinden was, inclusief biografie en primaire en secundaire bibliografie. In de lemma’s is er aandacht voor bijvoorbeeld thematiek (en de ontwikkeling daarvan), visie op de wereld, kunstopvatting en de relatie tussen leven en werk. Met dit boek markeren we het eindpunt van het Kritisch Literatuur Lexicon. In de zomer van 2021 heeft de nieuwe redactie besloten om het lexicon op een waardige manier te beëindigen. Het feit dat de Digitale Bibliotheek voor de Nederlandse Letteren (dbnl) het archief van het lexicon uit de jaren 1980-2015 digitaal beschikbaar heeft gesteld, speelde een belangrijke rol bij het nemen van die beslissing. We heffen het Kritisch Literatuur Lexicon op, maar maken het tegelijk eindelijk digitaal en open access beschikbaar voor de vakgemeenschap. Met dit boek voegen we daar de stukken aan toe die in de periode 2017-2021 door de nieuwe redactie van het Kritisch Literatuur Lexicon voor publicatie waren voorbereid. Daarmee bieden we de auteurs alsnog de gelegenheid om hun artikel te publiceren en bieden we de lezers van het digitale lexicon zestien mooie stukken over auteurs die in het archief van het lexicon ontbraken of met een niet-geactualiseerd lemma vertegenwoordigd waren.".
- 01GMWTBAAJXHH3QS8P0C8MDN0B abstract "Background and objectives: Infections and micronutrient deficiencies are widespread health issues in Africa. Vitamin A (VA) deficiency remains an endemic public health concern, with its health consequences mostly affecting infants, young children and pregnant and lactating women. In Burkina Faso, VA deficiency is especially prevalent during the rainy season. The aim of this study was to assess the association between common infections and inflammatory status and VA status in children living in a malaria endemic rural area in Burkina Faso, and the effect of season on this association. Material and methodology: Two community-based cross- sectional studies were conducted in a malaria endemic area of Burkina Faso and have included 115 children of 36 - 59 months of age. The 13C-retinol isotope dilution test (RID) determined VA total body store (TBS) and total liver reserve (TLR). Malaria infection was assessed using rapid diagnosis test and malaria smear, intestinal parasites were assessed by stool microscopic examination, and inflammation indicators, C reactive proteins (CRP) and Alpha-1-acid glycoprotein (AGP) were assessed in venous blood by ELISA. The association between VA status and infection status was tested by a multiple linear regression. Results: No VA deficiency (<0.1 mol/g liver) was detected using sensitive RID method in the study population. TBS median (Q25-Q75) was 430.8 (289.9 – 620.6) mol and TLR median was 0.79 (0.55 - 1.20) mol/g liver. One-fourth of study participants were found to have hypervitaminosis A (>1.0 mol/g liver). Elevated CRP and AGP were respectively detected in 9% and 26% children. Malaria was diagnosed in 10 % of the children. Significant but weak association was found between CRP concentration and VA status (β=0.055, p=0.009). There was no association between malaria status, AGP and exposition to digestive parasites with VA status. The association between CRP and VA status has a seasonal pattern (β= 0.591, p= 0.001). Conclusion: In this area of Burkina Faso where infections are common none of the children had VA deficiency. An association was found between acute inflammatory markers and VA status, which was stronger during the rainy season.".
- 01GMWW0ZA3W6WP1WQR1YAWA1QE abstract "Het ontwerp van programmawet voorziet een hervorming van het fiscaal stelsel voor auteursrechten en naburige rechten. De bedoeling daarvan is om het toepassingsgebied van het belastingregime beter af te lijnen. Binnen het voorziene wettelijke kader is niet duidelijk of software nog in aanmerking komt. De minister lijkt nu aan te geven dat dit niet het geval zou zijn door een nauwere fiscale definitie van beschermde “werken” te hanteren.".
- 01GMWWFCYTNQHYAJ8PVGE25X77 abstract "Le projet de loi-programme prévoit une réforme du régime fiscal des droits d’auteur et des droits voisins, avec l’objectif de mieux délimiter son champ d’application. Mais le cadre légal envisagé ne permet pas de clairement déterminer si les logiciels sont encore éligibles. Le ministre semble indiquer que ce ne serait pas le cas, du fait de l’adoption d’une définition (fiscale) plus restreinte des « œuvres » protégées.".
- 01GMWWFF9E8BEWVM0H1HE2RS4F abstract "This article applies the theory of mediatisation of religion and public pedagogy to explore three related historical issues of the Anglican Church media activities in Nigeria. Firstly, it briefly examines the media activities of the Church Missionary Society (CMS) in Nigeria. The aim is to understand how Anglican missionaries established and engaged with the media. Secondly, it examines the media establishments of the Church of Nigeria Anglican Communion (CoN). The objective is to outline the media outlets of the Church of Nigeria and to produce a thick description of the background of the Advent Cable Network Nigeria (ACNN), a television station of the CoN and to identify the link between the media activities of the CMS and the Church of Nigeria. Thirdly, this article presents an analysis of the theology of media for the Church of Nigeria. The aim is to understand the biblical and theological assumptions that underpin the media endeavours of the Church of Nigeria and how it relates with the concept of public pedagogy.".
- 01GMWXKD95Z2FYFPX9MQ371C9D abstract "The adoption of a psychological approach can shed new light on scholarly problems originating from different disciplines, and even be the driving force towards resolving them. On the other hand, the exploration of new topics can yield worthwhile expansions of existing psychological literatures. OBJECTIVE. Here I will present the case of the cognitive impact of classical language education. Across decades and countries, the value of studying Latin and Ancient Greek has been the subject of fierce public debate. Proponents suggest that it transfers to other cognitive domains, resulting in improved language skills, reasoning etc. To this day, however, the alleged transfer benefit amounts to little more than an apologetic topos used by classicists, not (yet) proven by scientific evidence. METHOD. For the first time in the history of this educational debate, I am applying psycholinguistic research paradigms regarding the cognitive effects of multilingualism and L2 acquisition to classical language learning. To be precise, I am conducting a longitudinal observational study with a matched comparison group design in several Flemish schools, in order to assess cognitive transfer to native language abilities, school achievement, and general cognitive abilities. RESULTS & CONCLUSION. As my empirical study is still ongoing, presented data will be preliminary. The expectation is that whilst controlling for other variables, particularly initial cognitive ability, cognitive transfer will be found. Since a lot of the classic research on cognitive transfer has relied solely on lab-based experiments, field data from an already existing and heavily discussed educational situation is an invaluable contribution to this branch of research. Moreover, the focus on classical languages is an interesting addition to the literature concerning the bilingual advantage, as well as to the field of L2 acquisition. In short, I will present a fruitful example of the application of psychological methods in a multidisciplinary research endeavour.".
- 01GMWXVFTCB7WTC98BZA5QATNR abstract "Does studying Latin and Ancient Greek yield any further advantages aside from knowledge of these languages and cultures? The value of classical language education in contemporary society is being questioned from a utilitarian angle, but proponents have long claimed there are transfer benefits, such as improved linguistic and other cognitive abilities. If such transfer benefits were to be empirically confirmed, it could move future educational policy in new directions. In brief, the time is right for a rigorous evaluation of the cognitive impact of this study programme. I will present the seminal study I am currently conducting in Flemish secondary schools to investigate various potential transfer effects of classical language study, using longitudinal assessment of pupils in different study options. In my presentation I will pay special attention to my measuring instruments, which are all electronically administered and scored, and to the correlations between measured variables I have established.".
- 01GMWXXNJ1ZSCPZHVFZ11CZSRE abstract "If there is one study option that undergoes societal pressure, it is the study of classical languages (CLs). I will first clarify the position of the CLs within the Western educational system and society at large, and then discuss some of the existing tensions in light of empirical evidence. For centuries, Latin and Ancient Greek were the basis of all Western non-vocational education (Wachter 2008). The tradition of instructing youngsters in these ancient languages and their corresponding literatures and cultures persists to this day. Although official bodies allocate less and less class hours to it and enrolment is steadily dropping, a non-negligible number of pupils still spends a considerable amount of time on Latin and/or Ancient Greek (Vereeck 2020). In some countries, among which Croatia, Serbia and Greece, these courses are even mandatory for all pupils. In numerous other European countries, they are a compulsory part of academically oriented streams. Elsewhere there are no governmental obligations, but the CLs continue to stand their ground nonetheless. Flanders is a striking example thereof: this tiny region alone counts tens of thousands of CL-pupils. Throughout the twentieth century, however, the CLs gradually lost the self-evident status and time-honoured prestige they previously enjoyed, and with that their privileged position in education as well (Sparks et al. 1995). Especially since the post-war period the educational value of the CLs has been openly and incessantly questioned. The principal criticisms that have been voiced against CL-education are inspired by either one of two societal tendencies which are found worldwide: egalitarianism and utilitarianism. Thus the value of CL-instruction became the subject of an international public debate which keeps raging on. To briefly summarise the two main criticisms, the egalitarian argument consists of the accusation that CL-education is elitist, while the gist of the utilitarian argument is that these so-called dead languages are not useful in contemporary society and therefore not worth the time spent on them. The latter is also connected with the economic demand for more technically schooled employees. Very often Science, Technology, Engineering and Mathematics (STEM) studies, which have been actively promoted by European authorities in recent years, are presented as the modern and useful counterpart of CLs (Duyck et al. 2017). Both criticisms have been vigorously countered by classics teachers and other proponents of CL-education. Interestingly, in response to the utilitarian argument, they have long claimed that besides the linguistic and cultural-historical knowledge you acquire, there are also indirect uses of studying CLs. According to these proponents, it improves language ability in both native and foreign tongues, hones various reasoning skills, fosters critical and independent judgement et cetera. Such indirect benefits are referred to as “transfer” (Barnett and Ceci 2002). But does the study of CLs really transfer to other cognitive domains? So far, we have no convincing evidence for this claim. It is a fact that (former) CL-pupils tend to outperform their peers on a variety of measures (Bracke and Bradshaw 2020), from standardised language tests, over medical entrance exams, to success rates in higher education. The key question here is whether this is due to a transfer effect from CL-study or to preselectivity, i.e. to a higher cognitive ability present a priori in said pupils. The aim of my talk is to shed new light on the aforementioned arguments and counterarguments. I will do so by touching upon current tendencies in CL-instruction and, above all, by sharing the first results of a seminal study on the cognitive impact of CL-learning I am presently conducting. The data collected so far will show to which extent preselectivity can actually explain higher achievement in CL-pupils. Barnett, Susan, and Stephen Ceci. 2002. ‘When and Where Do We Apply What We Learn? A Taxonomy for Far Transfer’. Psychological Bulletin 128 (4): 612–37. Bracke, Evelien, and Ceri Bradshaw. 2020. ‘The Impact of Learning Latin on School Pupils. A Review of Existing Data’. The Language Learning Journal 48 (2): 226–36. Duyck, Wouter, Mark Janse, and Jorie Soltic. 2017. ‘Stem voor Grieks en Latijn. Wat overleeft, leeft’. In Vorming door onderwijs. Humaniora tussen verleden en toekomst, 169–84. Leuven: Acco. Masciantonio, Rudolph. 1977. ‘Tangible Benefits of the Study of Latin. A Review of Research’. Foreign Language Annals 10 (4): 375–82. Sparks, Richard, Leonore Ganschow, Kay Fluharty, and Sherwin Little. 1995. ‘An Exploratory Study on the Effects of Latin on the Native Language Skills and Foreign Language Aptitude of Students with and without Learning Disabilities’. The Classical Journal 91 (2): 165–84. Vereeck, Alexandra. 2020. ‘Leerlingenaantallen in perspectief’. Prora 25 (4): 6–11. Wachter, Rudolf. 2008. ‘Latin and European Language History’. In Meeting the Challenge. International Perspectives on the Teaching of Latin, 135–49. Cambridge: Cambridge University Press.".
- 01GMWZ090JWGQAT44W7YS05R05 abstract "Ungulate populations are increasing across Europe with important implications for forest plant communities. Concurrently, atmospheric nitrogen (N) deposition continues to eutrophicate forests, threatening many rare, often more nutrient-efficient, plant species. These pressures may critically interact to shape biodiversity as in grassland and tundra systems, yet any potential interactions in forests remain poorly understood. Here, we combined vegetation resurveys from 52 sites across 13 European countries to test how changes in ungulate herbivory and eutrophication drive long-term changes in forest understorey communities. Increases in herbivory were associated with elevated temporal species turnover, however, identities of winner and loser species depended on N levels. Under low levels of N-deposition, herbivory favored threatened and small-ranged species while reducing the proportion of non-native and nutrient-demanding species. Yet all these trends were reversed under high levels of N-deposition. Herbivores also reduced shrub cover, likely exacerbating N effects by increasing light levels in the understorey. Eutrophication levels may therefore determine whether herbivory acts as a catalyst for the “N time bomb” or as a conservation tool in temperate forests.".
- 01GMWZ0MSD1Y6NK6BFDHZV7KV9 abstract "Seeking information when anxious may help reduce the aversive feeling of uncertainty and guide decision-making. If information is negative or confusing, however, this may increase anxiety further. Information gathered under anxiety can thus be beneficial and/or damaging. Here, we examine whether anxiety leads to a general increase in information-seeking, or rather to changes in the type of information and/or situations in which it is sought. In two controlled laboratory studies, we show that both trait anxiety and induced anxiety lead to a selective alteration in information-seeking. In particular, anxiety did not enhance the general tendency to seek information, nor did it alter the valence of the information gathered. Rather, anxiety amplified the tendency to seek information more in response to large changes in the environment. This was true even when the cause of the anxiety was not directly related to the information sought. As anxious individuals have been shown to have problems learning in changing environments, greater information-seeking in such environments may be an adaptive compensatory mechanism.".
- 01GMWZ30GEV6DM50NKFBDR4M7V abstract "Information can strongly impact people's affect, their level of uncertainty and their decisions. It is assumed that people seek information with the goal of improving all three. But are they successful at achieving this goal? Answering this question is important for assessing the impact of self-driven information consumption on people's well-being. Here, over five experiments (total N = 727) we show that participants accurately predict the impact of information on their internal states (e.g., affect and cognition) and external outcomes (e.g., material rewards), and use these predictions to guide information-seeking choices. A model incorporating participants' subjective expectations regarding the impact of information on their affective, cognitive, and material outcomes accounted for information-seeking choices better than a model that included only objective proxies of those measures. This model also accounted for individual differences in information-seeking choices. By balancing considerations of the impact of information on affective, cognitive and material outcomes when seeking knowledge, participants became happier, more certain and made better decisions when they sought information relative to when they did not, suggesting that the actual consequences of receiving information aligned with their subjective expectations.".
- 01GMWZ4Q2JB7E9TTVNA19E98WX abstract "Theories of prefrontal cortex (PFC) as optimizing reward value have been widely deployed to explain its activity in a diverse range of contexts, with substantial empirical support in neuroeconomics and decision neuroscience. Similar neural circuits, however, have also been associated with information processing. By using computational modeling, model-based functional magnetic resonance imaging analysis, and a novel experimental paradigm, we aim at establishing whether a dedicated and independent value system for information exists in the human PFC. We identify two regions in the human PFC that independently encode reward and information. Our results provide empirical evidence for PFC as an optimizer of independent information and reward signals during decision-making under realistic scenarios, with potential implications for the interpretation of PFC activity in both healthy and clinical populations.".
- 01GMWZ90X1WQM4XFF0XV2YJRQ6 abstract "Fatigue in multiple sclerosis (MS) is a highly disabling symptom. Among the central mechanisms behind it, an involvement of sensorimotor networks is clearly evident from structural and functional studies. We aimed at assessing whether functional/structural balances of homologous sensorimotor regions-known to be crucial for sensorimotor networks effectiveness-decrease with MS fatigue increase. Functional connectivity measures at rest and during a simple motor task (weak handgrip of either the right or left hand) were derived from primary sensorimotor areas electroencephalographic recordings in 27 mildly disabled MS patients. Structural MRI-derived inter-hemispheric asymmetries included the cortical thickness of Rolandic regions and the volume of thalami. Fatigue symptoms increased together with the functional inter-hemispheric imbalance of sensorimotor homologous areas activities at rest and during movement, in absence of any appreciable parenchymal asymmetries. This finding supports the development of compensative interventions that may revert these neuronal activity imbalances to relieve fatigue in MS.".
- 01GMWZA0XJQZQ5V575WPER77XB abstract "The baby schema concept was originally proposed as a set of infantile traits with high appeal for humans, subsequently shown to elicit caretaking behavior and to affect cuteness perception and attentional processes. However, it is unclear whether the response to the baby schema may be extended to the human-animal bond context. Moreover, questions remain as to whether the cute response is constant and persistent or whether it changes with development. In the present study we parametrically manipulated the baby schema in images of humans, dogs, and cats. We analyzed responses of 3-6 year-old children, using both explicit (i.e., cuteness ratings) and implicit (i.e., eye gaze patterns) measures. By means of eye-tracking, we assessed children's preferential attention to images varying only for the degree of baby schema and explored participants' fixation patterns during a cuteness task. For comparative purposes, cuteness ratings were also obtained in a sample of adults. Overall our results show that the response to an infantile facial configuration emerges early during development. In children, the baby schema affects both cuteness perception and gaze allocation to infantile stimuli and to specific facial features, an effect not simply limited to human faces. In line with previous research, results confirm human positive appraisal toward animals and inform both educational and therapeutic interventions involving pets, helping to minimize risk factors (e.g., dog bites).".
- 01GMX174B83YHYHDKXM02PBCDR abstract "This study was conducted to further explore the possible mechanism behind the finding that rural teachers are disadvantaged for participation in inquiry-based working compared to their urban counterparts. School organisation factors are the most obvious mediating variables since they can be easily connected with wider school regional features and with the behaviour of teachers. The contributions of two organisational factors, school research culture and school research infrastructure were studied. A multilevel structural equation model was developed based on data collected from 5566 Chinese teachers working in 114 primary schools. The results reveal the disparity in teacher-perceived school research culture and infrastructure between rural teachers and urban teachers. Perceived school research culture is positively related to teacher involvement in inquiry-based working, and mediates the rural-urban gap of teacher involvement in inquiry-based working at the between-level. The implications of these results and the theoretical, methodological, and practical contributions of this study are discussed.".
- 01GMX2WMNS1GPVWXWF9CPE0FPR abstract "This paper addresses the necessary complementarity between a translanguaging and named language-perspective by critically examining risks of 'overshooting' when a translanguaging view is theoretically posited as the ultimately superior (sociolinguistic) theory of language use and learning in today's multilingual world.".
- 01GMX3YRBKT1CW13XDJZ17F7QJ abstract "Addiction is a complex psychiatry condition manifested by the loose of control over drugs or nondrug behaviors despite harmful consequences. In this study, we argue that the exploration-exploitation dilemma and its computational mechanisms can help us understand this disorder and its underlying mechanisms. We tested problem gamblers – for whom the confounding effects of substance abuse typically observed in drug addiction are nullified - and controls in a sequential decision-making task and adopted a reinforcement learning model so as to explore the mechanisms involved. The results show an unbalance in how problem gamblers solved decision problems, where reward learning and information control mechanisms both appear to play key roles. By studying addiction under the exploration-exploitation framework, this study opens up a new way of investigating this disorder and of reinterpreting its main symptoms as impairments of both learning and control mechanisms.".
- 01GMX43X6JHZJJ7YEX9NZW0QXM abstract "Recent advancements in psychology, behavioral economics, and neuroscience have shown the human pursuit of knowledge to be an essential aspect of human cognition. It drives intellectual development, is integral to social interactions, and is crucial for learning, decision-making, and goal-directed behavior. Information appears to be valuable in and of itself, even when it has no apparent use, whereas at other times, instrumental information is actively and paradoxically avoided. With this complex role, a wide range of neural mechanisms can be deployed to assign value to information and drive decisions to seek (or avoid) information. Evidence points toward key roles for the mesolimbic system and the prefrontal cortex in these processes. Specifically, two different networks appear to be involved in the implementation of information-seeking behaviors. One network, overlapping with areas involved in processing primary and monetary rewards, appears to drive a general preference for information, as well as valence-dependent information-seeking. The other network, independent of reward processing, is recruited when information is acquired to reduce uncertainty. In this chapter, we review some of the most recent discoveries in the field to provide an overview of the neural basis of information-seeking.".
- 01GMX46RRZVJXY2H2J31S9BAP6 abstract "Humans constantly search for and use information to solve a wide range of problems related to survival, social interactions, and learning. While it is clear that curiosity and the drive for knowledge occupies a central role in defining what being human means to ourselves, where does this desire to know the unknown come from? What is its purpose? And how does it operate? These are some of the core questions this book seeks to answer by showcasing new and exciting research on human information-seeking. The volume brings together perspectives from leading researchers at the cutting edge of the cognitive sciences, working on human brains and behavior within psychology, computer science, and neuroscience. These vital connections between disciplines will continue to lead to further breakthroughs in our understanding of human cognition.".
- 01GMX4894Z5DYCX6TRVR2ZDC8V abstract "Police resources are scarce public goods and have to be used with maximum efficiency. One dimension of efficiency is the spatial and temporal alignment of police presence to calls-for-service. The research question of interest in this paper is whether the police are where and when they are needed most. We employ a supply and demand model based on police presence and the occurrence of calls for police service. We use GPS data from 100 tracked police vehicles and data on calls-for-service from a mid-sized European police agency. We find that most segments receive relatively more police presence than calls-for-service alone would warrant and that calls-for-service as well as emergency calls show little spatiotemporal variation. Further, police presence is found to be the main driver in changes regarding police provision across streets. We discuss the need to develop more evidence-based frameworks to investigate the effectiveness of police patrol and response deployment. The insights can assist police chiefs to identify streets with high demand for police services and to understand the predictability of police demand within their jurisdiction.".
- 01GMX4NHES08D43X86HYAZ7APC abstract "This study demonstrates how temporal summary statistics can be a guiding tool for big data analyses to unravel temporal patterns of crime and police presence. Simple indicator statistics were used to identify temporal clusters of crimes and police presence, and to investigate potential links between the two. The methodology was applied on an anonymized police database, including reported crime events and police presence data, from a medium-sized European police department. The results illustrated that certain crime types occurred more during the day (e.g., burglaries), while others were more prevalent at night (e.g., drug crimes, motorbike and car theft). Police presence showed dispersed temporal patterns and little temporal focus on any type of crime. The research shows that temporal summary statistics can be used to support an explorative analysis of big datasets and guide subsequent spatiotemporal analyses of crime and police data. The summary statistics offer an accessible approach to analysing extensive datasets of policing activity and improving evidence-based policing strategies.".
- 01GMX53S96VR59VBFEQPHV8XKK abstract "Research Question What were the spatiotemporal patterns of police patrol in a major European city across the pre-COVID year of 2019, how did these patterns change over time, and to what extent did the concentrations of patrol correspond to concentrations of crimes? Data We analyzed more than 77 million GPS signals from 130 police patrol cars showing where and when police patrols were present in police districts and street segments. We also plotted location, time and days of the week of the locations, and times of more than 50,000 recorded crimes. Methods We calculated concentration ratios within both crimes and patrols relative to their distributions in time and space. We then compared the concentration ratios for crime to the concentration ratios for patrols. We concluded the analysis by comparing the extent to which concentrations of crime and patrol locations and times were overlapping. Findings We found that police patrols, much like crime, were concentrated on a small proportion of street segments. Yet spatiotemporal police presence is unrelated to local levels of crime and crime concentration. Relative to temporal crime concentrations, police patrols were substantially under-concentrated from 1500 to 0100 h, all day on Fridays, and the entire months of June, July, August, and December. There was very little overlap in patrol concentrations with crime concentrations. Conclusions After three decades of research showing crime prevention benefits of patrol concentrations on micro-level crime concentrations, police in one European city concentrate patrol presence at locations, times, days, and months where crime is not concentrated. Whether this conclusion can be reached in other cities will depend on replications of this study, both in Europe and other continents.".
- 01GMX61VKT76MM6YCHMPCD97C0 abstract "The reference (pristine) concentrations of total dissolved phosphorus (TDP) in surface waters are difficult to define in lowland regions because of their high population density. Here, we estimated reference conditions of TDP from head-waters and their riverbed sediments (n = 140) in old forests. Surface waters and sediments were collected in the low-land region of Belgium as transects starting in 20 different old forests (before 1775; pristine) to up to 1.5 km outside the forest edge (disturbed). Sediment P concentrations in disturbed samples readily increased with increasing distance from the borders of old forests. The P mobilized from the sediments to the overlying water was also measured in lab-oratory incubations to mimic P release during seasonal redox cycles. The sediment respiration was larger in disturbed than in the reference sediments. Disturbed sediments released more P during anaerobic than aerobic incubations, while reference sediments did not show such a difference. The mean TDP in the reference surface water samples is 57 mu g TDP L-1 [95 % confidence interval 41; 72], very close to the pre-industrial background previously estimated for the Scheldt river. The 90th percentile of the reference water is 137 [110; 180] mu g TDP L-1. That P90 is just under the prevailing TP limit of 140 mu g P L-1, illustrating that this limit is very close to the upper baseline of reference conditions. The P75, often proposed as the threshold for high ecological status, was 84 [55; 122] mu g P L-1. This study showed that soil or sediments in old forests might serve to identify reference conditions. The well-established summer peaks of TDP in lowland rivers are unlikely to occur in pristine areas.".
- 01GMX6E9X3CME3DHPBJYKWQED2 abstract "A recent exhaustive analysis of lithic assemblages from four wetland sites belonging to the 5th and early 4th millennium cal BC, all situated in the Lower-Scheldt basin of NW Belgium (East Flanders), has revealed the presence of numerous faceted tools. Unknown prior to the 5th millennium, these tools constitute a totally new type of tool within hunter-gatherer contexts of the Scheldt basin. Typologically, they seem to resemble similar tools found within Early Neolithic contexts in northern France and Belgium, suggesting some kind of connection between the last hunter-gatherers from the sandy lowlands and the first farmer-herders from the loess area. Within this paper, faceted tools from both communities will be presented and discussed in the light of the neolithization process of the Scheldt basin. For the first time, a large scale use-wear analysis was conducted on these artefacts.".
- 01GMXBAZ1200C58SX11J417PM6 abstract "Proline homopolymer motifs are found in many proteins; their peculiar conformational and dynamic properties are often directly involved in those proteins' functions. However, the dynamics of proline homopolymers is hard to study by NMR due to a lack of amide protons and small chemical shift dispersion. Exploiting the spectroscopic properties of fluorinated prolines opens interesting perspectives to address these issues. Fluorinated prolines are already widely used in protein structure engineering – they introduce conformational and dynamical biases – but their use as 19F NMR reporters of proline conformation has not yet been explored. In this work, we look at model peptides where Cγ-fluorinated prolines with opposite configurations of the chiral Cγ centre have been introduced at two positions in distinct polyproline segments. By looking at the effects of swapping these (4R)-fluoroproline and (4S)-fluoroproline within the polyproline segments, we were able to separate the intrinsic conformational properties of the polyproline sequence from the conformational alterations instilled by fluorination. We assess the fluoroproline 19F relaxation properties, and we exploit the latter in elucidating binding kinetics to the SH3 (Src homology 3) domain.".
- 01GMXDFT6JBFXJJD0NC8HGK5YB abstract "Early diagnosis of fusarium head blight (FHB) presence and intensity in wheat can assist decision support for reducing disease spread and minimizing mycotoxin contamination in the grain. Although hyperspectral data was used successfully for the detection of FHB, using the traditional machine learning methods, these rely on time-consuming manual feature extraction, requiring expert skills. This study explores the use of deep learning models which can automatically extract FHB features. Images were generated from single lines hyperspectral (400-750 nm) data collected from wheat canopy in the laboratory and fed to a convolutional neural network (CNN) for pixel classification into two classes of healthy or FHB infected pixels. Four different types of image conversion schemes were explored, which resulted in a spectral (line & bar) graph, compressed spectral line graph and 2D generated band image. Eight different pre-trained lightweight CNN models that require limited computing re-sources were utilized. The preliminary analysis showed that DarkNet 19 model using the spectral line graph images from both smoothed and unsmoothed data resulted in the best accuracy and F1 score of 100 % with a prediction score of 1 for the sample test dataset. The application of feature visualization using an occlusion sensitivity map was able to elucidate the spectral features responsible for the high accuracy for classification. The results suggest the robustness of the developed method for recognition of pixels corresponding to the FHB infected and healthy ears under the laboratory conditions that motivate for potential development with field data.".
- 01GMXNRA1XRGRFGAVD0620FW11 abstract "Design Thinking (DT) remains a fuzzy concept when applied to education. This prompted the present scoping review (2008‐2022), following Arksey and O’Malley’s framework. From 2853 Web of Science articles, only 172 met inclusion and exclusion criteria. Results show: (a) There is no agreed definition of DT. (b) There is a variety of tools, techniques and models used to support DT. (c) Most‐assessed outcomes of DT are about creativity, teamwork, and problem solving. There were 100 out of 172 studies that included an evaluation of DT interventions. Research instruments were mainly based on student self‐reports. Most empirical studies reported a positive impact. (d) Only 12 empirical studies involved control groups, while 37 adopted a pre‐test and post‐test design. Intervention duration ranged from 90 minutes to one year. The median of the number of participants was around 47. DT presents an interesting research agenda but also there is a need for robust evidence‐based intervention studies.".
- 01GMZ1NMXBTJMY4B0GJ361TQCH abstract "Procedures of party leadership selection have attracted considerable scholarly attention in recent years, but voting motives of party members in leadership elections have not been fully studied yet. This paper presents a new model of voting in party leadership elections that is inspired by previous models that were mostly tailored to more exclusive selectorates (such as the parliamentary party). We adopt an inductive research strategy that is based on an open question in member surveys that were held on the occasion of three Belgian party leadership elections. As a result, we obtain a comprehensive model with eight different vote motivations: policy positions, electability, competence, perceptions of personality traits, socio-demographic characteristics, personal relationships, party-organisational reasons and negative voting. Our findings also show that the kinds of motivations that are put forward by members are dependent upon the number of contenders.".
- 01GMZ1T6PN4G3DXS9ZY1184A8G abstract "Many Western parties have opened up the process of leadership selection to party members under the noble premises to democratize the party. Yet, this might just be window-dressing as party leadership selection is often a coronation rather than an open contest. We argue that the preparation phase preceding the actual election phase is crucial in understanding the balance between the impact of party members and the steering of the party elite. This study compares the preparation phase of two leadership contests after losing elections in one party, the Flemish Christian-democratic party in Belgium: one with a single candidate and one with an exceptionally high number of candidates. Our analysis, based on 22 in-depth elite interviews, demonstrates that leadership elections are influenced by a cluster of different influencing actors, but in particular by what we label the “last person standing” whose candidacy is identified as the most effective mechanism to influence the nomination process. Other (slightly less effective) influencing mechanisms include encouragements, discouragements and the diffusion of an ideal profile for the future party leader.".
- 01GMZ41JKB97PDYYYWB8B8YSEY abstract "Atomically thin two-dimensional (2D) semiconductors are extensively investigated for optoelectronic applications that require strong light–matter interactions. In view of such applications, it is essential to understand how (photo)excitation alters the non-linear optical response of these materials under high carrier density conditions. Broadband transient absorption (TA) spectroscopy is by now a widely used tool to study the semiconductor physics in such highly excited systems. However, the complex interplay between different many-body interactions in 2D materials produces highly congested spectral information and an ensuing non-trivial non-linear photo-response, thereby masking the desired intrinsic photophysics. Herein, we outline a concise roadmap for analyzing such congested datasets based on examples of TA analysis of various 2D materials. In particular, we emphasize the synergy between an initial qualitative understanding of the transient photo-response based on line shapes and their derivatives and a consequent quantitative spectral deconvolution backed by such insights.".
- 01GMZ8321DVH0ECK5GVFMMRZA4 abstract "This paper takes as point of departure the centrality of recognition in the contemporary political landscape. More specifically, it focuses on those struggles for recognition known as identity politics. We depart from the hypothesis that modern theories of recognition, more specifically those advanced by Axel Honneth and Nancy Fraser, cannot adequately accommodate the demand for the recognition of difference. Our contribution with this article is to argue that, in a discussion of struggles for recognition, the distinction between affirmative and transformative strategies must be taken into account. We argue that affirmative approaches to recognition risk resulting in the negation of difference and reproducing the exclusive social order. By thinking through the implications of an affirmative approach to recognition, we aim to contribute to the understanding of failed attempts at recognition. We conclude with a tentative outline of the conditions for a transformative approach that aspires to meet the demands of actors in movements for social justice and avoid the problems of the affirmative approach.".
- 01GMZB29V2W3B3THVE1F67C5N8 abstract "Bayesian optimization is a popular tool for optimizing time-consuming objective functions with a limited number of function evaluations. In real-life applications like engineering design, the designer often wants to take multiple objectives as well as input uncertainty into account to find a set of robust solutions. While this is an active topic in single-objective Bayesian optimization, it is less investigated in the multi-objective case. We introduce a novel Bayesian optimization framework to perform multi-objective optimization considering input uncertainty. We propose a robust Gaussian Process model to infer the Bayes risk criterion to quantify robustness, and we develop a two-stage Bayesian optimization process to search for a robust Pareto frontier, i.e., solutions that have good average performance under input uncertainty. The complete framework supports various distributions of the input uncertainty and takes full advantage of parallel computing. We demonstrate the effectiveness of the framework through numerical benchmarks.".
- 01GMZHDEFVG0Q81972PFY1K3FD abstract "De geriatrische patiënt wordt gekenmerkt door zijn of haar leeftijd en ouderdom. Dit belangrijke concept van ouderdom wordt op twee manieren gebruikt: een chronologische en een symbolische. Met ouderdom hangen vaak verschillende stereotypen en associaties vast die een impact kunnen hebben in hoe we ons verhouden tot oudere patiënten. Wanneer we een te stereotiep beeld aanhouden van ouderdom kan dit bovendien aanleiding geven tot ‘ageism’. Centraal is ook de medische blik op ouderdom en de vraag in welke mate we ouderdom en daarbij horende kwalen kunnen benaderen als normaal en natuurlijk of eerder moeten beschouwen als aandoeningen? Dit zijn cruciale en actuele vragen, ook al omdat zich in een sneltempo een belangrijke demografische ontwikkeling aan het voltrekken is. Een toenemend aantal mensen bereikt een oude leeftijd waardoor de populatie oudere patiënten groeit. Welke medische zorg deze krijgen is een belangrijke klinische én maatschappelijke vraag.".
- 01GMZHP4JPW4A8E97CAENB07KC abstract "Food waste is one of society's biggest problems, with huge ecological, economic and social consequences. Hence, there is a necessity to derive a better insight in how consumers can be triggered to avoid food waste. Although it is generally known that motivations are important drivers of human behavior, limited attention has been paid to motivations in the food waste context and no viable measurement instrument exists that systematically takes into account the different motivations underlying the avoidance of food waste. Current scales related to food waste concern encompass attitude and awareness items only. The current paper aims to fill this gap and develops a 21-item Motivation to Avoid Food Waste (MAFW) scale. Since consumers may be driven by different motivations to avoid food waste, special attention is paid to the multidimensionality of food waste avoidance motivations. Specifically, the MAFW-scale consists of four motivations: environmental, moral, financial and social motiva-tions. Three studies demonstrate the scale's internal reliability, test-retest reliability, nomological validity, and predictive validity. The MAFW-scale fosters research into the genesis of consumers' food waste behaviors, and can serve as a tool to segment and target (un)motivated consumers.".
- 01GMZHXYSRQBEXW2RGPBCT5D8G abstract "Composite materials are subjected to increasing importance in critical components commonly used for automotive, aerospace and other modern industrial sectors. Yet, these composites are quite susceptible to damages and defects which can be introduced during the manufacturing and/or operational life. To assure the structural performance of composite parts, a non-destructive testing (NDT) technique is necessary to detect and evaluate the damages. Guided wave imaging (GWI) is capable to interrogate large areas with a sparse array in a short period and thus can be a perfect candidate for time-efficient damage detection. Though, the current sparse array GWI requires a very precise baseline measurement, making it impractical for actual applications. In this research, nonlinear wave phenomena is exploited in order to remove the need for baseline data, and as such to make sparse array GWI widely applicable.".
- 01GMZHXYSRQBEXW2RGPBCT5D8G abstract "Non-destructive evaluation of large composite components can be done efficiently with sparse array guided wave imaging (GWI). Though, current sparse array GWI requires a very precise baseline measurement, making it impractical for actual applications. In my research, I exploit nonlinear wave phenomena in order to remove the need for baseline data, and as such to make sparse array GWI widely applicable.".
- 01GMZNFBV297ZRW0MF1G7B4W2F abstract "How the Journal d’un curé de campagne is written is intimately linked to the night because of the narrator’s insomnia. We will demonstrate that this night is the expression of an inner night, through the carmelite mysticism of John of the Cross. The writing is purified by the silence and anguish of the priest's mystical night: we will see that his writing becomes a prayer, that is to say, the hosting of divine and human voices in silence, based on Jean-Louis Chrétien’s phenomenological approach of prayer. This idea of writing will allow us to understand the relationship of Bernanos himself to his own writing: this nightly writing listens and gives voice to those who have none.".
- 01GMZNYMXB7S0QPKQ79CV1SY48 abstract "Rond 1850 raakte Rusland verwikkeld in wat nadien bekend kwam te staan als de Krimoorlog, een geopolitieke clash met het Verenigd Koninkrijk, Frankrijk, het Ottomaanse rijk en Piemont-Sardinië die aan meer dan 600.000 mensen het leven zou kosten. Het schiereiland was het voornaamste oorlogstoneel, wat mede verklaart waarom het huidige Russische regime er in 2014 op gebrand was om de Krim – tot dan een gebied met uitgebreide autonomie in Oekraïne – te annexeren. In 1855 en 1856 schreef een jonge Russische officier onder de initialen L.N.T. drie verhalen waarin hij de belegering en uiteindelijke val van het bolwerk Sebastopol beschreef: ‘Sebastopol in december’, ‘Sebastopol in mei’ en ‘Sebastopol in augustus’. De op dat moment nog vrijwel onbekende Lev Nikolaevitsj Tolstoj (1828-1910) was na de publicatie van de verhalen in Ruslands bekendste, door Poesjkin opgerichte tijdschrift Sovremennik (De Tijdgenoot) definitief gelanceerd als auteur. De zogenaamde ‘dikke tijdschriften’ waren in het negentiende-eeuwse Rusland het publicatiekanaal bij uitstek; ook andere literaire grootheden als Toergenjev en Dostojevski publiceerden er hun romans in afleveringen. Kort na de door Rusland verloren oorlog bundelde Tolstoj de verhalen in het boek Voennye rasskazy (Oorlogsverhalen) en sindsdien staan ze als drie-eenheid bekend als de ‘Sevastopol’skie rasskazy’, de Sebastopolverhalen. In de loop der tijd werd de trilogie opvallend vaak in het Nederlands vertaald: er zijn in totaal zeven verschillende vertalingen in omloop gekomen.1 Ik concentreer me hier op de eerste drie vertalingen, verschenen in het korte tijdsbestek tussen 1886 en 1904. Daarna was het wachten tot 1966, toen Van Ditmar de Sebastopol-vertellingen publiceerde in de vertaling van A.W. van Agtmael en F.J.M.C. van Schoonderwalt. Tijdens de zoektocht naar het vertaal-DNA van Tolstojs Sebastopolverhalen ga ik na welke de bronteksten van de verschillende vertalingen zijn en in welke mate de afzonderlijke vertalingen onderling verwant zijn. Daarbij maak ik gebruik van het instrumentarium van ‘genetic translation studies’, waarin de documentatie en analyse van het vertaalproces centraal staan, met een focus op kladversies en revisies (zie bijvoorbeeld Nunes 2020). Onder vertaalgenetica wordt hier (met Boulogne 2011: 308) verstaan: het systematisch analyseren van een vertaling met als doel de tekst(en) die eraan ten grondslag liggen in kaart te brengen en hun impact na te gaan. Het uitgangspunt is een opmerking van Gideon Toury (1995: 74) dat ‘a multitude of candidates for a source text may exist’ en het is dan ook zaak om eerst de mogelijke Russische brontekst(en) te identificeren. In een volgende stap probeer ik de genetische code van de Nederlandse vertalingen te kraken: op welke tekst(en) zijn ze gebaseerd? De notie ‘tekst’ slaat in dit geval op de (tussen-)vertaling en/of (uiteindelijke) brontekst op basis waarvan de vertaling werd gemaakt. Op die manier wil ik de stamboom van de Nederlandse Sebastopolverhalen reconstrueren.".
- 01GMZV5TZVA4F9JN0HRJYG19SW abstract "RFX-mod is an experimental fusion device, which contributes to plasma physics studies both in reversed field pinch (RFP) and tokamak configurations. Its high flexibility, due to an active magnetohydrodynamic (MHD) control system and the modular coils power supply (CPS) system, allowed operating RFX-mod in a wide range of experimental conditions with a plasma current up to 2 MA. Experiments with such high plasma current allowed the study on new promising confinement regimes, dominated by a self-organization process with the generation of a helical structure in the plasma core. Presently, RFX-mod is under a significant upgrade (RFX-mod2) to extend the operational scenarios increasing the proximity between the conductive shell and the plasma. This main modification of the magnetic front-end, together with other main improvements, is expected to increase the performance of the machine in both magnetic configurations. In the frame of the studies to exploit the new potential of RFX-mod2 achieving a higher plasma current and longer flat-top duration, a solution based on additional magnetic energy storage has already been proposed. The study of RFP physics at higher plasma current could be crucial to confirm positive trends, such as electron temperature and persistence of quasi single helicity states with the plasma current, and to explore and achieve improved confinement states. This article presents an alternative reconfiguration of the poloidal power supply system of RFX-mod2 based on a combined resistor-capacitor energy transfer system. This system allows to store energy in capacitor banks during the first phase of the plasma current ramp-up and release it to the plasma when the magnetizing current changes polarity, driving the plasma current over 2.5 MA. The proposed upgrade does not involve radical poloidal CPS modifications, maintaining the present converters number and ratings and remaining within the power limits of the main power transformers (300 MVA).".
- 01GMZV9T0WQX5QX4M2012EE0EN abstract "RFX-mod is an experimental fusion device built to explore and study plasma physics, especially in Reversed Field Pinch (RFP) configuration. RFX-mod allowed performing experiments with a plasma current up to 2 MA and obtaining stationary self-organized helical plasmas. Considering the results achieved so far, a significant upgrade of the device (RFX-mod2) is presently being implemented. This paper presents the feasibility study of a significant increase of the plasma current and flat-top duration via a limited upgrade of the RFX power supply system, without overstressing the poloidal windings or overcoming the power limits of the main step-down transformers (300 MVA) and maintaining the present set of thyristor converters units. The application of this concept to RFX-mod2 will be studied starting from the RFX-mod configuration, focusing on the needed modification of the present circuits and the desired improved performance. The increase of the maximum plasma current and flat-top duration, under the current and mechanical limits of the coils, can be reached using additional magnetic energy storage and a complete revision of the configuration and operating principle of the power supply system of the poloidal field coils. With this new operational concept, during the charging phase, the magnetizing winding is charged along with an additional inductor, which acts as an energy storage reservoir. The stored energy, in the order of 100 MJ, is transferred to the magnetizing winding, and thus to the plasma, via transfer resistors in the last phase of the plasma current ramp-up, to reach values of plasma current up to 2.6 MA.".
- 01GMZVB341FBJSRC6YD0CNC5WT abstract "A new Magnetic Energy Storage and Transfer (MEST) system, which can improve the power handling in fusion experiments, has been recently conceived. It is particularly suitable to feed the DEMO Central Solenoid (CS), in principle without the need for resistive switching networks (SNUs), but can be applied to supply the Poloidal Field (PF) coils too. The operating principle of this system, described for one central solenoid circuit, is to pre-charge an additional Superconducting Magnetic Energy Storage (SMES) coil at least up to twice the maximum energy expected in the load (CS) and to transfer the energy from one to the other and viceversa via switched-capacitor. With this approach, the energy is exchanged between the load and the storage system, thus flattening the active power profile to be required from the ac side and substantially nullify the reactive power absorbed. p In this paper, the application of this concept to the European DEMO is studied, starting from the present circuit configuration and from the current and voltage scenario under consideration for the plasma breakdown and ramp-up. A first tentative rating of the system components is reported, discussing also the future R&D steps to explore the industrial feasibility of such a scheme.".
- 01GMZVPRVQZJKAAN9F8A05VN2J abstract "In this paper, we propose a systematic and time-efficient approach to calibrate 2D VARANS-VOF models for simulation of wave interaction with porous plate in numerical wave tank. To reach this goal, we develop a data-driven approach in combination with numerical and experimental data to figure out the optimal empirical coefficient associated with linear and non-linear drag force coefficients (a, beta). Advanced gradient boosting decision trees algorithms (GBDT) are adopted to capture the accuracy of the prediction model. Although only limited samples, for instance 72 samples are generated and chosen to train and test the prediction model, the GBDT model is able to identify the trend in non-linear influence of model parameters. The advantage of GBDT algorithm can obviously be seen through the regression analysis with very high regression coefficient (R-2 > 0.99). The developed model is subsequently employed for a large range of considered parameters as input features of the models to predict the possible hydrodynamics characteristics. The smallest mean squared error between predicted and experimental results, which is 0.00204, is found and used to determine the best performing combination of these model parameters. The numerical model together with selected values of empirical coefficients is then validated using available experimental data in literature. The free surface elevations in front of and behind the structure from the numerical model are nearly identical with the experimental data.".
- 01GMZYHF0F15V3JKMR721VJFQ1 abstract "Cardiovascular disease often occurs with silent and gradual alterations of cardiac blood flow that can lead to the onset of chronic pathological conditions. Image-based patient-specific Computational Fluid Dynamics (CFD) models allow for an extensive quantification of the flow field beyond the direct capabilities of medical imaging techniques that could support the clinicians in the early diagnosis, follow-up, and treatment planning of patients. Nonetheless, the large and impulsive kinematics of the left ventricle (LV) and the mitral valve (MV) pose relevant modeling challenges. Arbitrary Lagrangian-Eulerian (ALE) based computational fluid dynamics (CFD) methods struggle with the complex 3D mesh handling of rapidly moving valve leaflets within the left ventricle (LV). We, therefore, developed a Chimera-based (overset meshing) method to build a patient-specific 3D CFD model of the beating LV which includes a patient-inspired kinematic model of the mitral valve (LVMV). Simulations were performed with and without torsion. In addition, to evaluate how the intracardiac LV flow is impacted by the MV leaflet kinematics, a third version of the model without the MV was generated (LV with torsion). For all model versions, six cardiac cycles were simulated. All simulations demonstrated cycle-to-cycle variations that persisted after six cycles but were albeit marginal in terms of the magnitude of standard deviation of velocity and vorticity which may be related to the dissipative nature of the numerical scheme used. The MV was found to have a crucial role in the development of the intraventricular flow by enhancing the direct flow, the apical washout, and the propagation of the inlet jet towards the apical region. Consequently, the MV is an essential feature in the patient-specific CFD modeling of the LV. The impact of torsion was marginal on velocity, vorticity, wall shear stress, and energy loss, whereas it resulted to be significant in the evaluation of particle residence times. Therefore, including torsion could be considered in patient-specific CFD models of the LV, particularly when aiming to study stasis and residence time. We conclude that, despite some technical limitations encountered, the Chimera technique is a promising alternative for ALE methods for 3D CFD models of the heart that include the motion of valve leaflets.".
- 01GN02MHQXVPJ096DYZ5JSZ73K abstract "Based on the dual trend of more women running for office and campaigns becoming more negative, we can ask ourselves how gender affects the attack strategies of political actors. Studies underline the differential use of negative campaigning between male and female candidates and how both experience different pay-offs. However, existing research focuses solely on the United States and, therefore, a system with candidate-centered campaigns, weak party organizations, and winner-takes-all competitions. This paper wants to address these shortcomings by proposing Belgium, known for its strong parties and low gender stereotype presence, as a least-likely case. We conducted a quantitative content analysis of 11.440 Tweets sent by 286 politicians holding a realistic position on the ballot during the 2019 regional and Federal elections. Bivariate and multivariate results show strong confirmation that these gender differences in negative campaigning are indeed replicable in a Western European party-centered context as women are significantly less likely to go negative, and critical differences are noticeable between the male and female tendency to opt for policy-based versus trait attacks.".
- 01GN0374SPS8W8DQSGHASR6WJA abstract "The wind collision region (WCR) in a colliding wind binary (CWB) is a particularly violent place, as such, it is surprising that it is also a region where significant quantities of interstellar dust can form. In extreme cases, approximately 30 per cent of the total mass-loss rate of a system can be converted into dust. These regions are poorly understood, as observation and simulation of these systems are difficult. In our previous paper, we simulated dust growth in CWB systems using an advected scalar model and found our model to be suitable for qualitative study. For this paper, we simulated the periodic dust forming CWB (WCd) system WR140 with our dust model, to determine how dust growth changes over the systems periastron passage. We found that dust production increases significantly at periastron passage, which is consistent with IR emission of the surrounding dusty shell. We also find that the dust production rate of the system decreases rapidly as the stars recede from each other, though the rate of decrease is significantly lower than the rate of increase during periastron passage. This was found to be due to strong cooling and its associated thermal instabilities, resulting in cool, high-density pockets of gas in the WCR where dust forms. The WCR also shows a degree of hysteresis, resulting in a radiative post-shock flow even when the stars are separated enough for the region to behave adiabatically.".
- 01GN0374SXKXYD5HAV20K3ZK4C abstract "Dust production is one of the more curious phenomena observed in massive binary systems with interacting winds. The high temperatures, UV photon flux, and violent shocks should destroy any dust grains that condense. However, in some extreme cases, dust production yields of approximately 30 per cent of the total mass-loss rate of the stellar winds have been observed. In order to better understand this phenomenon, a parameter space exploration was performed using a series of numerical models of dust producing carbon phase Wolf-Rayet (WCd) systems. These models incorporated a passive scalar dust model simulating dust growth, destruction, and radiative cooling. We find that reasonable dust yields were produced by these simulations. Significant changes in the dust yield were caused by changing the mass-loss rates of the stars, with a greater mass-loss rate contributing to increased dust yields. Similarly, a close orbit between the stars also resulted in higher dust yields. Finally, a high-velocity wind shear, which induces Kelvin-Helmholtz (KH) instabilities and wind mixing, drastically increases the dust yields.".
- 01GN03KRWXGF2G3MWPS5GEZ3WP abstract "Star formation from the interstellar medium of galactic disks is a basic process controlling the evolution of galaxies. Understanding the star formation rate (SFR) in a local patch of a disk with a given gas mass is thus an important challenge for theoretical models. Here we simulate a kiloparsec region of a disk, following the evolution of self-gravitating molecular clouds down to subparsec scales, as they form stars that then inject feedback energy by dissociating and ionizing UV photons and supernova explosions. We assess the relative importance of each feedback mechanism. We find that H2-dissociating feedback results in the largest absolute reduction in star formation compared to the run with no feedback. Subsequently adding photoionization feedback produces a more modest reduction. Our fiducial models that combine all three feedback mechanisms yield, without fine-tuning, SFRs that are in excellent agreement with observations, with H2-dissociating photons playing a crucial role. Models that only include supernova feedback-a common method in galaxy evolution simulations-settle to similar SFRs, but with very different temperatures and chemical states of the gas, and with very different spatial distributions of young stars.".
- 01GN046S8ZK2RVA5GF9DHT03GD abstract "Transediting Newspaper Fiction Bulgakov’s The Master and Margarita serialized During the 19th and 20th centuries, newspapers and other periodicals harvested large amounts of fiction. These stories and novels were usually split up into a number of episodes, becoming recurrent features and doing so enhancing the readership loyalty of the periodical, as readers were enticed to read the next episode. At the same time, a considerable sample of these so-called feuilletons were used to disseminate ideologically suitable deemed content in a highly pillarized society, where most newspapers voiced their publisher’s political orientation (e.g. a political party, or a trade union). By their very nature, serialized novels were subject to a number of constraints. Not only did they need to fit the newspaper’s format, but as they were serialized, stories and novels were divided up in episodes. As a result, abridged translations are not uncommon in periodicals. The choice of what is selected for translation is revealing, but perhaps even more essential and telling are the (often) deliberate choices to deselect certain paragraphs, subplots or other entities of text. This sets in motion a number of interventions to compensate for the abridged content. Adding sentences to smoothen transitions, restructuring plot elements, and highlighting distinct features all belong to the cut-and-pasting connected with media processes but are nevertheless not alien to the periodical translator’s toolbox either. In my paper, I focus on the 1968 publication of Michail Bulgakov’s The Master and Margarita in the Dutch Catholic newspaper De Volkskrant. The novel contains three storylines, each foregrounding a different genre, so The Master and Margarita is at once a historical novel, a lovestory, and a satire. For the novel to fit the publication in 146 installments, the editors deemed a large number of adaptations necessary, “otherwise the reader-in-episodes would get lost” in the novel’s layered structure. I will draw on these adaptations to identify practices of simplification and ‘transediting’ (translated and edited) with text-surgical methods such as addition, substitution or deletion in an effort to understand the functionality of the translation for its target audience. The editing and adapting of translations offers perspectives on the daily consumption of literary texts and their cohabitation in the highly constrained environment of a newspaper. In my paper I will argue that both translation studies and periodical studies, and language-driven research at large can considerably benefit from incorporating translated periodical fiction into its research agenda. References Baker, Mona 1995 Corpora in Translation Studies. An Overview and Some Suggestions for Future Research. Target. International Journal of Translation Studies 7/2: 223-243. Fólica, Laura, Diana Roig-Sanz & Stefania Caristia (eds.) 2020 Literary Translation in Periodicals: Methodological challenges for a transnational approach. (Benjamins Translation Library vol. 155) Amsterdam: Benjamins. O’Connor, Anne 2019 Translation in nineteenth-century periodicals. Materialities and modalities of communication. Translation and Interpreting Studies 14/2: 243-264. Özmen, Ceyda 2019 Beyond the Book: The Periodical as an ‘Excavation Site’ for Translation Studies. TranscUlturAl 11/1: 3-21. Philpotts, Matthew 2012 The Role of the Periodical Editor: Literary Journals and Editorial Habitus. Modern Language Review 107/1: 39-64. Schäffner, Christina 2012 “Rethinking Transediting.” Meta 57, 4: 866–883. Van Doorslaer, Luc 2011 The relative neglect of newspapers in translation studies research. In: Chalvin, Luc, e.a. (eds.), Between Cultures and Texts: Itineraries in Translation History, 45-54. Frankfurt: Peter Lang.".
- 01GN1D804ZZVZZ8E0XQTFGFNJZ abstract "Among the many entities people in the past could identify with and feel loyal to, the ethnic group appears to have been far less important than the religious community, the social class, the local community and the clan. Ascribe to ethnic consciousness the same feelings of loyalty people socialized in contemporary nation states experience toward their national community obviously is a projection of a modern mental make-up into the past. Under Ottoman rule Orthodox Christians constituted a single community, within which ethnic distinctions played a secondary role. The fact that into the nineteenth century ethnonyms could refer to religious, vocational and social groups as well is an additional indication of the limited importance that was attached to ethnic appurtenance. This contribution describes the main cultural features of the Orthodox Christian community in the Ottoman Empire and offers two additional case studies. The first deals with the Bulgarian poet Grigor Părličev, whose path to Hellenization was smoothed by a his primal Orthodox Christian mental make-up that did not consider assuming an other ethnic identity as a violation of one’s fundamental duties his or her religious community. The second case is related to the goudilas, Hellenized Bulgarians in Plovdiv, who changed their identity as a result of collective upward social mobility. Both cases illustrate the irrelevance of ethnic identity to those concerned.".
- 01GN1K75VTF0ESQTWV26KNV889 abstract "Concreteness describes the degree to which a word's meaning is understood through perception and action. Many studies use the Brysbaert et al. (2014) concreteness ratings to investigate language processing and text analysis. However, these ratings are limited to English single words and a few two-word expressions. Increasingly, attention is focused on the importance of multiword expressions, given their centrality in everyday language use and language acquisition. We present concreteness ratings for 62,889 multiword expressions and examine their relationship to the existing concreteness ratings for single words and two-word expressions. These new ratings represent the first big dataset of multiword expressions, and will be useful for researchers interested in language acquisition and language processing, as well as natural language processing and text analysis.".
- 01GN1KJEWNYQGD8TQV10Q8WX9M abstract "Morphological awareness contributes to vocabulary acquisition and reading in bilingual children who learned English after their native language. In line with these considerations, we further investigated L2 processing in late adult bilinguals where questions related to morphology need to be clarified. French-English speakers (N = 92) were assessed for three morphological awareness stages: lexical semantic knowledge, syntactic knowledge, and distributive knowledge. We investigated whether the evolution of morphological awareness was related to L2 proficiency and whether it was facilitated by the presence of suffixes shared in L1 and L2. Our results confirmed the influence of language proficiency at each stage of morphological awareness. However, the hypothesis of an advantage of suffixes shared between French and English was not confirmed as no clear advantage was found for those suffixes. Our findings are discussed in line with the morphological congruence hypothesis and compared with the previous results in the literature.".
- 01GN1KPEKBRC764GTWAECV7HBF abstract "We present five studies aimed at developing an L1 vocabulary test for English-speaking university students. Such a test is useful as an indicator of crystallized intelligence and because vocabulary size correlates well with reading comprehension. In the first study, we tested 100 written words with four answer alternatives, based on Nation's Vocabulary Size Test. Analysis suggested two factors, which we interpreted as the possible existence of two types of difficult words: unknown words for general knowledge and unknown words for specialized knowledge. In Study 2, we attempted to develop a vocabulary test for each type of word, and these tests were then validated in Study 3. Since the test for general words proved too easy for the target population, we improved it in a fourth study by creating and testing more difficult items. Finally, a fifth study was conducted to validate the new test. Unexpectedly, Study 5 found a high correlation (r = .82) between the general knowledge vocabulary test and the specialized knowledge vocabulary test, suggesting that they measure the same latent factor, contrary to our initial assumption. Both tests have high reliability (r > .85) and correlate well (r > .4) with general knowledge, author recognition, and reading comprehension. In addition, a collection of other language tests was used and improved to verify the validity of the vocabulary tests. An exploratory factor analysis of all tests identified three factors (text comprehension, crystallized intelligence, and reading speed), with the vocabulary tests loading on the factor crystallized intelligence, which in turn correlates with reading comprehension. Structural equation modeling confirmed the interpretation.".
- 01GN1WW4G14F79NW3SY0S32D5C abstract "Maatschappelijk werkers op de sociale dienst van het OCMW worden dagelijks geconfronteerd met de vaststelling dat veel mensen in financiële problemen raken door een te hoge woonkost in verhouding met hun inkomen. Vele OCMW’s geven een aanvullende steun om de woonkosten te kunnen dragen. Reeds jaren staat in alle verkiezingsprogramma’s betaalbaar wonen als een van de grote uitdagingen of problemen die aangepakt moeten worden. Vandaag stellen we vast dat verre van iedereen in een betaalbare, kwaliteitsvolle woning kan wonen. Het grote aantal dak- en thuislozen die door de recente lokale daklozentellingen naar boven komen, is daar het manifeste bewijs van. Er is een wooncrisis aan de gang en die is zodanig ernstig dat een aantal organisaties de Vlaamse overheid zelfs via juridische weg willen overtuigen om de nodige maatregelen te treffen en het woonbeleid aan te passen. Woonbeleid gaat onder meer over de toegang tot wonen, de kwaliteit van de woningen, de woonzekerheid en uiteraard ook over de betaalbaarheid van wonen. Kunnen wonen in een kwaliteitsvolle woning die geen onevenredige hap uit het gezinsbudget neemt, is voor veel mensen een bepalende factor. Het laat hen toe om deel te nemen aan de samenleving, om zichzelf te ontplooien, om kansen te bieden aan hun kinderen … In dit cahier gaan we dieper in op wonen en plaatsen we het aspect betaalbaarheid voorop.".
- 01GN2B0DY39MZG6TZ47CE7HERW abstract "L’épée d’Onnen fut découverte en 1896 lors de l’extraction de tourbe à environ 1,5 m de profondeur. Il s’agit d’une épée dite « à antennes », d’après les spirales qui forment son pommeau, datée de la fin de l’âge du Bronze (IXe siècle av. J.-C.). Aujourd’hui conservée au Groninger Museum (numéro d’inventaire 1896/I 4), elle n’a jamais fait l’objet d’une réelle étude ni été correctement publiée. Son récent examen à l’agence du patrimoine culturel des Pays-Bas nous donne l’occasion de présenter en détail cette épée et les techniques employées lors de sa production dans l’optique de discuter de son origine.".
- 01GN2B0DY39MZG6TZ47CE7HERW abstract "The Onnen sword was found in 1896 while exploiting a peat bog, about 1.5 m deep. It is a so-called “antennae” sword, named after the spirals at the top of the pommel and it dates back to last phase of the Bronze Age (ca. 9th century BC). The Groninger Museum now curates the sword with inventory number 1896/I 4. Although this sword is already mentioned in the archaeological literature, it was never correctly published. Its recent study in the cultural heritage agency of The Netherlands gives us a good opportunity to make a detailed presentation as well as to investigate its production techniques to discuss its possible origins.".
- 01GN6XE74CX1NC0R8E5HZ55PGF abstract "Wind speed measurement depends on the efficiency of the anemometer sensors. In fact, the anemometer wind speed sensors, mounted on top of the wind turbine nacelle, give the wind speed measurements to the controller devices. These measurements obtained from the anemometers represent the turbulent wind speed and cannot represent the wind speed upstream of the rotor blades. For that, Effective Wind Speed (EWS) will be estimated by applying linear and nonlinear Kalman Filter methods to Wind Turbines System (WTS). In this study, the variable wind speed is computed numerically based on the estimation values obtained from the linear KF, while it is directly estimated from the nonlinear KF. Furthermore, Backward Euler Approximation is used to perform the discretization of the continuous-time state space model of WTS based on KF estimators. In this paper, the efficiency of each filter is investigated on a wind turbine using a two-mass drive train interconnected by a common spring and damper. The comparative studies show that the two estimators have high accuracy estimates at the steady-state with greater than 95% similarity between the estimated and measured wind speeds. However, the nonlinear KF has better performance than linear KF at the transient-state due to its very small time response. These results achieved are justified by computing the covariance and the Correlation Coefficient (CC) between the measured and estimated wind speeds for each 5 ms. The covariance curves obtained are positive, while the CC curves are close to one at the steady-state for both estimators.".
- 01GN70F3WD6NPRHYP2293Q37HZ abstract "Despite the knowledge that cell-mediated immunity (CMI) contributes to the reduction of severe influenza infection, transmission, and disease outcome, the correlates of protection for cell-mediated immunity remain still unclear. Therefore, measuring the magnitude and quality of influenza-specific T cell responses in a harmonized way is of utmost importance to improve characterisation of vaccine-induced immunity across different clinical trials. The present study, conducted as part of the FLUCOP project, describes the development of a consensus protocol for the intracellular cytokine staining (ICS) assay, in order to reduce inter-laboratory variability, and its qualification. In order to develop a consensus protocol, the study was divided into different stages. Firstly, two pilot studies evaluated critical parameters in the analytical (read-outs) and post-analytical (gating strategies and data analysis) methods applied by eight different laboratories within the FLUCOP consortium. The methods were then harmonized by fixing the critical parameters and the subsequent consensus protocol was then qualified by one FLUCOP member. The antigen-specific cell population was defined as polypositive CD4(+) T cells (i.e. positive for at least two markers among CD40L/IFN gamma/IL2/TNF alpha), which was shown to be the most sensitive and specific read-out. The qualification of this consensus protocol showed that the quantification of polypositive CD4(+) T cells was precise, linear and accurate, and sensitive with a lower limit of quantification of 0.0335% antigen-specific polypositive CD4(+) T cells. In conclusion, we provide the description of a harmonized ICS assay, which permits quantitative and qualitative evaluation of influenza vaccine-induced T cell responses. Application of this harmonized assay may allow for future comparisons of T cell responses to different influenza vaccines. It may facilitate future assessments of potential correlates of protection with the promise of application across other pathogens.".
- 01GN78CKBAE94BQED3B54EAJDT abstract "Frailty is highly prevalent in old age and confers an important mortality risk. Although the causes of frailty are multiple, immunosenescence (IS)—predominantly driven by cytomegalovirus (CMV)—has been implicated in its pathophysiology. Thus far, research examining the association between IS and frailty states is sparse and equivocal. On the other hand, evidence is mounting in support of the view that frailty can be reversed, especially for those in the pre-frail stage. Therefore, we aimed to clarify the impact of CMV on IS and its relevance to pre-frailty. One hundred seventy-three persons aged 80 to 99 years were enrolled. Pre-frailty was defined according to Fried’s criteria. Anti-CMV IgG and serum IL-6 were measured using Architect iSystem and Luminex, respectively. T-cell phenotypes were determined using flow cytometry. The prevalence of pre-frailty was 52.6%, increased with age (p = .001), and was greater in men than women (p = .044). No relationship was found between pre-frailty and positive CMV serology. Further, CMV-seropositivity was significantly associated with less naïve cells, more memory and senescence-prone phenotypes (all p < .001). After adjusting for potential confounders, only IL-6, age and sex were predictive of pre-frailty. We conclude that the presence of pre-frailty is independent from CMV infection in very old subjects.".
- 01GN7V5T1E4AG7SMFQ77WT14AC abstract "Le présent article a pour objectif de présenter le système vocalique du lingala en examinant soigneusement et strictement le statut phonologique de chacune des unités vocaliques. Il fait une distinction claire entre les paires tonales et les paires phonologiques. Il considère le ton comme une unité distinctive dont la valeur n’est pas à associer à celle des voyelles. Ici, la langue lingala est étudiée en elle-même pour elle-même. Son système vocalique est décrit comme il est employé dans la communauté et non pas comme il devrait être Ainsi, ce travail s’oppose à tous les travaux considérant le lingala comme une langue à 7 voyelles et déplore le manque de preuves tangibles ou des paires justifiant l’identité phonologique des voyelles mi-ouvertes".
- 01GN7WH64PCR02KXYG2MPK27RD abstract "Cet article porte sur la conjugaison des verbes en lingala. Il présente les différents constituants de l’unité verbale en lingala avant de parler, tour à tour, de la succession des verbes ordinaires en lingala, de l’expression des temps simples dans cette langue, des auxiliaires marquant les temps composés et verbes sériels qui viennent modifier le sens des verbes ordinaires dans leur conjugaison. Ici, l’auteur fait une distinction claire entre auxiliant, auxilié et verbe sériels. Il soutient qu’un syntagme verbal peut contenir au plus six verbes. Il relève kozala « être », kosíla « finir », kobanda « commencer », kotí kala « rester » et kozela « attendre » comme les 5 principaux auxiliaires en lingala, et retient trois verbes sériels dans cette langue, à savoir : kosí(la) « finir », kolinga « vouloir », komeka « essayer ».".
- 01GN9P88PZEJHK1X8T44VKWHK7 abstract "The Tannuola Terrane of Tuva, which is located in the northern part of the Central Asian Fold Belt, formed as a result of island-arc and accretionary-collision events in the Early Paleozoic. Further tectonic evolution of the terrane is related to a multiple reactivations of large and mostly normal fault structures. In the middle Paleozoic, the extension of the crystalline basement of the terrane led to the active uplift of mafic melts along the faults to the surface and formation of subalkaline igneous rocks. The Mesozoic and Cenozoic igneous complexes within the Tannuola Terrane are unknown; thus, its tectonic evolution in the Mesozoic and Cenozoic could be considered only after a sedimentary record, which is preserved in the Mesozoic intermountain depressions of Tuva and adjacent Cenozoic Ubsunur Basin. This geological information, however, is insufficient for an exhaustive consideration of the regional tectonic regime taking into account the lack of confirmation of present-day precise methods. The understanding the Mesozoic-Cenozoic tectonic evolution of the Tannuola Terrane is impossible without the analysis of data on low-temperature thermochronology for rocks of the crystalline basement. In our study, fission-track analysis of apatite from 12 samples of the early Paleozoic granitoids of the Tannuola Terrane is conducted in order to recognize the stages of activation and tectonic stability within the absolute time scale. The analysis showed a wide range of ages from 83.4 +/- 4.7 (Late Cretaceous) to 35.5 +/- 2.2 (late Eocene) Ma at variation of the mean fission-track length from 11.4 to 12.3 mu m. The modeling of the thermal evolution of the basement of the Tannuola Terrane, which is based on these data, indicated three stages of tectonic activation of various origins and intensities divided by stages of tectonic quiet periods for the last similar to 185 million years: (i) similar to 185-135 Ma (Jurassic-Cretaceous), (ii) similar to 90-35 Ma (Cretaceous-Paleogene), and (iii) similar to 15-0 Ma (Neogene-Quaternary).".
- 01GN9PF1T72MGCPB4WG5M756RM abstract "The global environment experienced notable changes in the recent past of planet Earth. Satellite remote sensing has played an increasingly important role in monitoring and characterizing these changes. Being recognized as a sensitive indicator of global climate change, land surface phenology (LSP) observations by satellite remote sensing have received much attention in recent years; however, much less attention has been paid to the calibration of these observations using standardized procedures. Here, we propose a new approach to calibrating the satellite LSP products by developing a climotransfer function (CTF) based on a polynomial regression of the satellite-ground observation difference in key crop phenophases against climatic factors. We illustrate the model development and evaluation process with a case study of the cropland growing season in Northeast China (NEC) from 2001 to 2010 using the MODIS LSP product MCD12Q2 Collection 6 and the ground-observed crop phenology and climatic data from 98 agrometeorological stations across the region. Our results showed that the start of the cropland growing season (SOS) derived from MODIS data compared well to the ground-observed SOS, whereas the MODIS-derived season end (EOS) was delayed by 15.5 d, relative to ground observation. The MODIS-derived EOS was, therefore, spatiotemporally calibrated using a CTF model fitted to the satellite-ground difference in EOS ( increment EOS) versus two climatic factors, namely, the growing degree-days on the base temperature of 10 degrees C (GDD10) and cloud cover (CL). The calibrated MODIS data revealed that the cropland growing season in NEC tended to shorten at 4.5 d decade(-1) during 2001-2010, mainly driven by a significant delay in SOS at a similar rate, whereas no trend was detected for EOS. The calibrated data also revealed a significant shortening gradient of 1.7 d degree(-1) of latitude northward. These spatiotemporal patterns would have been erroneously characterized if calibration had not been applied. More attention is therefore called to the proper calibration of satellite LSP products prior to any meaningful applications.".
- 01GNA1EFCTEHN4FY2XGXPKR8ST abstract "Objective This systematic review aimed to examine pain, functional status and return to work after a multidisciplinary intervention, with or without additional workplace intervention, for (sub)acute low back pain among adults. Data sources A comprehensive search was completed (November 2022) in six electronic databases (Embase, MEDLINE, Web of Science, Cochrane, CENTRAL and Scopus) and in the reference list of all identified studies. Review methods The search results were screened against predefined eligibility criteria by two independent researchers. Included articles were systematic reviews or randomized controlled trials examining the effect of a multidisciplinary intervention, with or without workplace intervention, in working adults with (sub)acute low back pain. Relevant information was summarized and clustered, and the methodological quality and certainty of evidence were assessed respectively using the RoB 2-tool, the ROBIS tool and the GRADE criteria. Results The search resulted in a total of 3020 articles. After the screening process, 12 studies remained (11 randomized controlled trials and 1 systematic review), which studied overall 2751 patients, with a follow-up period of at least 12 months. Conclusions A multidisciplinary intervention is favorable compared to usual care for pain intensity and functional status but this is less clear for return to work. Comparable work-related effects were found when comparing a multidisciplinary intervention with a less extensive intervention, whereas uncertainties exist regarding outcomes of pain intensity and functional status. Furthermore, adding a workplace intervention to usual care and subdividing patients based on work-related characteristics seems beneficial for return to work.".
- 01GNAJ6G2ZA1S1ZMEPNWZ07TM6 abstract "Despite the importance of reasoning skills in today's knowledge-based society, students do not appear to possess sufficient arguing skills. This study aimed to examine the improvement of those arguing skills after implementing an intervention in grade 8. In total, 699 students participated, and data was collected using a document-based essay. Results show that students receiving limited and full arguing lessons showed significantly better progression from pre- to post-test compared to students not receiving the intervention.".
- 01GNAPFJNTM14B798KANYRMZWK abstract "FWO-funded project on finding a system within the corpus of regulae iuris in medieval jurisprudence".
- 01GNC3C5B0G0YMQNRY39ZWW4P9 abstract "Purpose: The aim of this clinical review was to summarise the existing knowledge on fall risk associated with benzodiazepines (BZDs) and Z-drugs in older people with focus on appropriate prescribing, including deprescribing. Methods: We conducted a literature search in June 2021 in PubMed and Embase with citation and reference checking. Personal reference libraries and international websites were also used. Keywords for the searches included “benzodiazepines”, “Z-drugs”, “falls”, “deprescribing”, “fall-risk-increasing-drugs”, “inappropriate prescribing”, “older people” and matching synonyms. We discuss use of BZDs and Z-drugs, potential fall-related adverse reactions, alternatives for and deprescribing of BZDs and Z-drugs in older persons. Results: BZDs and Z-drugs differ in fall-related adverse effect profile. They contribute to fall risk through orthostatic hypotension, dizziness and/or imbalance, sedation, muscular weakness, ataxia, etc. Fall incidents contribute significantly to mortality and morbidity. Therefore, there is a need for appropriate prescribing and use of BZDs and Z-drugs in older people. In practice, this means pertaining to a strict indication, strongly consider to non-pharmacological alternatives, limit use to the lowest dose and the shortest duration possible. Judicious deprescribing should be considered and encouraged as well. Practical resources, tools and algorithms are available to guide and assist clinicians in deprescribing BZDs and Z-drugs. Conclusions: Prescribing BZDs and Z-drugs should be done in a well-considered way in fall-prone older people. A good overview and insight in the fall-related adverse effects of these drugs, as well as the availability of different strategies to increase the appropriate use, including deprescribing initiatives, can assist clinicians in clinical decision-making.".
- 01GNCEBHFQQFRVH3KJ0HBS49JA abstract "Powered prosthesis actuation is a field where energy efficiency and mass are important characteristics. The motion requirements of high torque at low speed and low torque at high speed are difficult to effectively combine in a single electric motor. A possibility is to use an oversized direct–drive motor that can deliver the peak torque. However, this results in a heavy actuation system and low overall efficiency. A common practice is combining a smaller electric motor with a gear reduction system. In the literature, novel redundant electric actuation systems have been presented with or without locking mechanisms to mitigate this problem. In this work, we provide a comparison of multiple electrical actuation systems composed of electric motors, gear reduction systems and locking mechanisms. This is done using the gait cycle of a human ankle as a case study. An electric motor with a double stator and a single rotor combined with a gearbox shows the most promising overall results when taking energy loss, total mass and complexity of the system into account.".
- 01GNCHR2ZRSXX5XQNS0RV3EFVW abstract "Purpose of Review To provide an overview of mitral annular disjunction (MAD) and to discuss important challenges in diagnosis and management of MAD. Recent Findings MAD has regained interest in the context of sudden cardiac death (SCD) in patients with mitral valve prolapse (MVP), coined as the "arrhythmic" MVP syndrome. In addition, MAD in isolation was recently suggested to be associated with severe arrhythmia and SCD. There is a lack of consensus on the definition of MAD and the imaging modality to be used for diagnosing MAD, and the therapeutic implications of MAD remain uncertain. Furthermore, the exact mechanism underlying the association of MAD with SCD remains largely unexplored.".
- 01GNCV2MQQNG10ZA21MFS5WN08 abstract "Rice (Oryza spp.) is one of the major staple foods in Benin. Benin has increased rice production through the expansion of cultivation area rather than increasing rice yields. To better understand the factors affecting rice yields, a thorough understanding of the current rice production system characteristics and constraints is required. The present study identifies socio-economic characteristics and farmers’ practices affecting rice yields and suggests improved cultivation practices in the sector. Data were collected through semi-structured interviews, including socio-economic characteristics and rice cultivation practices from 230 randomly selected rice producers in North and Central Benin. Descriptive statistics and cluster analysis were used to group rice producers into different groups. Findings revealed that the proportion of rice producers having access to credit was low (33.5 %). Out of seventeen variables, only three (lowland rice cultivation, irrigated rice cultivation and total land cultivated area) discriminated best the rice producers in three (03) clusters with distinct characteristics in terms of socio-economics factors and cropping practices affecting rice yields. Most respondents (more than 70 %) did not practice crop rotation or fallow. This, together with low levels of chemical fertiliser applications and type of rice cultivation, explains poor rice production in particular in clusters 1 and 2. Yield enhancement is possible through the combination of lowland and irrigated cultivation performed by farmers in cluster 3 with the highest mean rice yield (3.8 t.ha-1). We suggest tackling the specific characteristics and needs of rice producers would more adequately help to improve rice yields. Interventions to enhance rice yields include training on best rice production practices, provision of input subsidies and access to irrigation tailored to the specific constraints and needs of each rice grower type. Finally, enabling access to credit will improve productivity of rice farmers in Benin.".
- 01GNEQE3GSB9EWHHYQR2KTBA0V abstract "The present paper addresses the tribological behaviour of new eco-friendly brake friction materials with rice husk (RH). Three formulations with different RH content (0%, 6% and 12%) were developed and subjected to the SAE J2522 test procedure, plus an extra high-temperature section, through a laboratory-scaled braking tribometer. At 300 C, RH acted holding wear debris and improving wear resistance due to the formation of large contact plateaus. At 550 C, RH's organic compounds degraded, leading to a greater material fade. Formulation 6% RH outperformed the others, showing the lowest wear. In this case, the effect of the hard and temperature resistant silica outweighed the degradation of the organic compounds.".
- 01GNETH9BA1VBC8EX785S9EJ2R abstract "Ultrasonic nanocrystal surface modification (UNSM) technique was applied to Inconel 718 alloy fabricated by laser powder-based direct energy deposition (LP-DED). The main aim of this study is to improve the mechanical properties and fretting wear behavior. No significant difference in surface roughness between the polished and UNSM-treated samples was made on purpose to avoid the effect of surface roughness on fretting wear behavior. The hardness and residual stress of the polished samples were increased after UNSM technique. Dry fretting wear behavior was evaluated using a ball-on-disk configuration at 24 and 60 degrees C. The results showed that the fretting wear resistance of the polished samples at both temperatures was enhanced, whereas an increase in temperature further enhanced the fretting wear resistance. In addition, possible factors influencing the enhancement in fretting wear behavior after UNSM technique in terms of fretting wear mechanisms and potential application were discussed.".
- 01GNEYVR06PB9483MDNPBB62YW abstract "Purpose: The aim of this study was to explore the effects of chronic low-dose-rate gamma-radiation at a multi-scale level. The specific objective was to obtain an overall view of the endothelial cell response, by integrating previously published data on different cellular endpoints and highlighting possible different mechanisms underpinning radiation-induced senescence. Materials and methods: Different datasets were collected regarding experiments on human umbilical vein endothelial cells (HUVECs) which were chronically exposed to low dose rates (0, 1.4, 2.1 and 4.1 mGy/h) of gamma-rays until cell replication was arrested. Such exposed cells were analyzed for different complementary endpoints at distinct time points (up to several weeks), investigating cellular functions such as proliferation, senescence and angiogenic properties, as well as using transcriptomics and proteomics profiling. A mathematical model was proposed to describe proliferation and senescence. Results: Simultaneous ceasing of cell proliferation and senescence onset as a function of time were well reproduced by the logistic growth curve, conveying shared equilibria between the two endpoints. The combination of all the different endpoints investigated highlighted a dose-dependence for prematurely induced senescence. However, the underpinning molecular mechanisms appeared to be dissimilar for the different dose rates, thus suggesting a more complex scenario. Conclusions: This study was conducted integrating different datasets, focusing on their temporal dynamics, and using a systems biology approach. Results of our analysis highlight that different dose rates have different effects in inducing premature senescence, and that the total cumulative absorbed dose also plays an important role in accelerating endothelial cell senescence.".
- 01GNF2KK98NW71RAC3YHC9W4H8 abstract "Radiation-Induced CardioVascular Disease (RICVD) is an important concern in thoracic radiotherapy with complex underlying pathophysiology. Recently, we proposed DNA methylation as a possible mechanism contributing to RICVD. The current study investigates DNA methylation in heart-irradiated rats and radiotherapy-treated breast cancer (BC) patients. Rats received fractionated whole heart X-irradiation (0, 0.92, 6.9 and 27.6 Gy total doses) and blood was collected after 1.5, 3, 7 and 12 months. Global and gene-specific methylation of the samples were evaluated; and gene expression of selected differentially methylated regions (DMRs) was validated in rat and BC patient blood. In rats receiving an absorbed dose of 27.6 Gy, DNA methylation alterations were detected up to 7 months with differential expression of cardiac-relevant DMRs. Of those, SLMAP showed increased expression at 1.5 months, which correlated with hypomethylation. Furthermore, E2F6 inversely correlated with a decreased global longitudinal strain. In BC patients, E2F6 and SLMAP exhibited differential expression directly and 6 months after radiotherapy, respectively. This study describes a systemic radiation fingerprint at the DNA methylation level, elucidating a possible association of DNA methylation to RICVD pathophysiology, to be validated in future mechanistic studies.".
- 01GNF3BDE3P2YGV82QY6KG22NM abstract "When transitioning from high school to university, young people must choose a programme that fits them. We argue that prospective students who can test this fit before starting the programme, will make a better choice. We propose an integrated framework where testing person-environment fit on ability beliefs, interests and sense of belonging possibly contributes to making the right choice. Dutch matching procedures are supposed to serve as a fit-test for prospective students choosing a university programme. 61 prospective students at four Dutch universities were interviewed on the role of matching in their programme choice. Different elements of matching appear to allow for testing fit but vary in which aspects of fit can be tested and the impact they have. It can be cautiously stated that the more aspects of fit that can be tested, the more a matching procedure impacts prospective students’ final programme choice.".
- 01GNF46KKVRGED2AGQG3VMWKFZ abstract "In the Netherlands, every year a substantial proportion of first-year students in higher education drop out due to a wrong program choice. Matching has been introduced to decrease wrong choices. In this dissertation we studied various types of matching procedures using questionnaire and study progress data from four Dutch universities as well as interviews with (prospective) students. Based on a perspective of person-environment fit, we used three aspects that are important in determining whether students fit with the program of their choice: 1) interests, 2) believe in their abilities, and 3) feeling at home in the program. In this dissertation, we examined the effectiveness of different types of matching procedures as experienced by students, and in relation to final enrollment and first-year student success. The interviews revealed that students believe that matching procedures can contribute to their understanding of the program. In general, the more aspects of fit with the program students could test in matching activities, the more useful the activity was found to be. Moreover, quantitative analyses showed that the types of matching that were found to be more useful by students involved programs where fewer students followed through on their initial enrollment; an indication that more students changed their minds after participating in a matching procedure. Enrollment rates have decreased since the introduction of matching for programs with intensive procedures, but not for less intensive programs, i.e. programs that only offer follow-up activities of questionnaire completion for students identified as at-risk based. Therefore, the introduction of matching procedures in general, and specifically the intensity of these procedures is a likely explanation for lower enrollment rates. Furthermore, we analyzed information from the matching questionnaires for the prediction of study success. It was found that indicators of fit, measured prior to the start of the program, were predictive of grade point average and number of credits earned in the first year of study. Moreover, most fit indicators in our study differed in strength and/or direction between STEM and non-STEM programs. For both STEM and non-STEM students, high school grade point average is the strongest predictor of academic success in the first year of study. However, our findings provide evidence that non-cognitive indicators, such as conscientiousness and interest in the program, are stronger predictors of academic success in the first year for non-STEM students than for STEM students. Lastly, we found that text-mining analyses of motivational texts in the matching questionnaires predicted first-year dropout as well as a set of student characteristics. However, when the motivational texts and student characteristics were combined, the prediction of dropout did not improve. Thus, on the one hand, the use of text mining techniques for dropout prediction seems promising. On the other hand, the fact that combining the text and numerical data does not improve the prediction of dropout in this study could indicate that they measure the same underlying concepts. Combining the findings of all studies provides interesting leads for improving matching procedures, for example in terms of necessary elements in these procedures.".
- 01GNFAJAAAW1KWE4ENKH5TZE6M abstract "Valt uw werk nog onder het hervormde fiscale gunstregime voor auteursrechten? Specialist Gauthier Vandenbossche, die werkt voor de Universiteit Gent en het advocatenkantoor Tiberghien, beantwoordt vragen van bezorgde Trends-lezers.".
- 01GNFJGXQJRXM75B0RMJ4EXHAK abstract "Predictive policing is the use of historical crime and other data in complex statistical models to predict where and when there is a high risk of new crime events. These predictions can then be used to direct police patrols proactively. Despite the increasing use and commercialisation of predictive policing worldwide, academic research into the methodological and operational dimensions of predictive policing is relatively limited. Since 2015 we have researched and tested several predictive crime models methodologically and operationally, based on police and other (big) data sources in several Belgian police districts. In this article, we summarise the results of six years of empirical research into predictive policing and look to the future of predictive policing research and practice.".
- 01GNFQJWBRVYCX0DQJE6W478VC abstract "In order to implement variable rate manure (VRM) in fields correctly, at rates that do not exceed the maximum allowable limits set by legislations, simulations are needed for different VRM scenarios [e.g., map-based (MB), sensor based (SB) and map-sensor-based (MSB)]. This study aims at the evaluation of these VRM scenarios based on simulation taking into account soil variability and manure limits set by legislations. A simulation software was designed and developed to allow the calculation of recommendations for variable rate manure application. Then, it was used to compare traditional uniform rate manure (URM) application against two VRM treatments in three commercial fields in Flanders, Belgium. Under each of the three treatments, two VRM schemes were evaluated, e.g., applying more manure to the more fertile zone (Kings scheme - KS) and more manure to the least fertile zone (Robin Hood scheme - RHS). Results revealed that RHS consumed 8.0% -15.3% less manure than the UR and 10.5% -15.8% than the KS approach only in one field. Due to the fact that rich parts were of larger area than the poor part, the KS method consumed more manure, hence, this was more expensive than RHS. When imposing the "MAP6" legislation limits, both KS and RHS consumed less than the case of without restrictions, reducing environmental risks due to reducing both nitrogen (N) and phosphorus (P) applied. Simulation results also presented that non-sensor-based methods (MB and URM) exceeded sensor-based (SB and MSB) rates by 2.8%-6.6%, when the mean value of real-time sensed P in manure was higher than the nominal P (measured by laboratory methods) value used for calculating the manure recommendation. We concluded that the manure consumed in VRM application depends on treatment approaches (MB, SB or MSB), application schemes (RHS or KS), measured manure quality, and the proportion of rich, medium, and poor fertility areas in a field.".
- 01GNFVXD22DSXF9X4JKPY0NCGJ abstract "Background Foodborne and zoonotic diseases such as brucellosis present many challenges to public health and economic welfare. Increasingly, researchers and public health institutes use disability-adjusted life years (DALYs) to generate a comprehensive comparison of the population health impact of these conditions. DALYs calculations, however, entail a number of methodological choices and assumptions, with data gaps and uncertainties to accommodate. Thisreview identifies existing brucellosis burden of disease studies and analyzes their methodological choices, assumptions, and uncertainties. It supports the Global Burden of Animal Diseases programme in the development of a systematic methodology to describe the impact of animal diseases on society, including human health. Methods/Principal findings A systematic search for brucellosis burden of disease calculations was conducted in pre-selected international and grey literature databases. Using a standardized reporting framework, we evaluated each estimate on a variety of key methodological assumptions necessary to compute a DALY. Fourteen studies satisfied the inclusion criteria (human brucellosis and quantification of DALYs). One study reported estimates at the global level, the rest were national or subnational assessments. Data regarding different methodological choices were extracted, including detailed assessments of the adopted disease models. Most studies retrieved brucellosis epidemiological data from administrative registries. Incidence data were often estimated on the basis of laboratory-confirmed tests. Not all studies included mortality estimates (Years of Life Lost) in their assessments due to lack of data or the assumption that brucellosis is not a fatal disease. Only two studies used a model with variable health states and corresponding disability weights. The rest used a simplified singular health state approach. Wide variation was seen in the duration chosen for brucellosis, ranging from 2 weeks to 4.5 years, irrespective of the whether a chronic state was included. Conclusion Available brucellosis burden of disease assessments vary widely in their methodology and assumptions. Further research is needed to better characterize the clinical course of brucellosis and to estimate case-fatality rates. Additionally, reporting of methodological choices should be improved to enhance transparency and comparability of estimates. These steps will increase the value of these estimates for policy makers. Author summary Brucellosis is a bacterial disease transmitted to humans by consumption of contaminated, unpasteurized milk or through direct contact with infected animals and their excretions. This disease causes production losses and has major economic impacts on individuals and communities. The disability-adjusted life year (DALY) is a metric for measuring the burden. It summarizes mortality (years of life lost) and morbidity (years lived with disability) into a single metric. This review aimed to identify existing brucellosis burden of disease studies and analyse their methodological choices, assumptions, and uncertainties. The results suggested that some parameters carry considerable uncertainty, particularly mortality and disease duration. This highlights the importance of strengthening routine reporting systems, collecting better mortality data and conducting further research on the course of brucellosis. Additionally, estimates of DALYs will benefit from a deeper understanding of the symptoms and the different sources of attribution. Finally, current reporting of methodological choices should be improved to enhance transparency, comparability, and consistency of brucellosis burden.".
- 01GNG2FXAZMG64FPS1EMK8ZXXV abstract "Although the variable-rate manure application (VRMA) offers a promising solution to overcome the shortcomings of the conventional uniform-rate (UR) application, effectively incorporating this technique into precision agriculture solutions presents a substantial challenge. This study entailed developing a quantitative analysis tool to calculate manure consumption, evaluate environmental risks, and compare different treatment schemes under different implementation scenarios. Firstly, a simulator was designed and developed in the LabVIEW development environment with MATLAB. Next, this tool was used to compare traditional UR application with VRMA, by which manure application rate was varied according to soil phosphorus (P) maps measured with an on-line visible and near infrared soil sensor, or according to data-fusion (DF)-based management zone (MZ) maps, developed by fusion of on-line measured soil properties and crop normalized difference vegetation index (NDVI). In the DF case, simulations included Robin Hood (RH) and Kings approaches, which meant to apply the largest manure application rate at the poorest fertility zones, or in the richest fertility zones, respectively. The implementation scenarios included both map-based (MB) without accounting for on-line manure sensing and map sensor-based (MSB) with on-line manure sensing in three commercial fields in Flanders, Belgium. The results revealed that the P-based-VRMA scheme consumed 1-13% less nitrogen (N) and P2O5 in the case of ignoring legislative limits, compared to the UR and this was true for the RH-VRMA scheme in all three fields and for the Kings-VRMA scheme in two out of three fields. This was because the P-based maps have larger rich fertility areas (e.g., large P concentration) than the MZ maps that both the RH and Kings approaches used. Furthermore, imposing the "MAP6 " legislation limits caused all VRMA schemes to consume less fertilizer than would be the case without restrictions, reducing environmental risks due to decreasing the amount of applied N and P2O5. According to the simulation results, the MSB scenario saved 6-9% manure compared to the MB scenario in the Pbased-VRMA scheme when the mean value of real-time sensed P(2)O(5 )in the applied manure was greater than the nominal values measured in the laboratory. Opposite results were observed in the UR, RH-, and Kings-VRMA schemes. The MSB was more expensive than the MB by 5-7%, when the mean N content of manure used for MSB was lower than that for MB. We concluded that the manure consumed in VRMA depends on treatment schemes, measured manure quality, imposing legislative limits, and the proportion of rich, medium, and poor fertility areas in a field. It is essential to impose the legislative limits to prevent over-applications of N and P2O5, while further agronomy study should evaluate the impact of these limits on crop responses.".
- 01GNHB3W8299Z55SSEZV12JAKP abstract "This article explores recent (1995-2018) dis-courses on 'multilingualism' in the Dutch-and French -medium written press in Belgium: how is the notion of 'multilingualism' thematised and evaluated and how does this reflect underlying historical, political and socio-economic sensitivities linked to the long-standing Belgian conflict? Based on a corpus of 1710 news articles and using Ruiz' (1984) language orientations as heuris-tics for quantitative and qualitative analyses, the study aims to provide objectification and reflexivity over an emotional, versatile and multi-layered language -ideological debate. Similar to (inter)national tenden-cies indicated in previous studies, our results generally reveal attention for and a positive bias towards (presti-gious) multilingualism, mainly linked to discourses of economic utility and plurality. Differences between the Dutch-and French-medium corpus, as well as recurring argumentative patterns in both corpora, however, can be traced back to ideological sensitivities of the Bel-gian conflict and point to the imperative historicity of Belgian language debates.".
- 01GNHJCR0W4XRNFAQGK0DNJDZK abstract "This article applies cognitive dissonance theory to the internationalisation of higher education sector to comment on tensions experienced by practitioners associated with their work's climate impact. The existing literature and relevant climate action drivers and challenges within the sector are reviewed. A case study of a global grassroot initiative, the Climate Action Network for International Educators, is considered to discuss possible solutions for how stakeholders can increase or decrease tensions at work in the relationship between international higher education and climate change. This article posits that cognitive dissonance theory can contribute to a better understanding of how dilemmas emerge at the intersection between international higher education and climate change to promote climate action within the sector. Avenues for future research are recommended.".
- 01GNHM2JDKH0JVBMYRXARW2CTC abstract "Glioblastoma is a grade IV glioma of heterogeneous nature, which complicates disease pathophysiology and biomarker research. The aim of this meta-analysis was to identify long non-coding RNAs (lncRNAs) and protein-coding genes (PCGs) that are differentially expressed in glioblastoma. Additionally, small RNA-seq of glioblastoma tissues was performed to identify differentially expressed microRNAs (miRNAs) compared to normal tissue controls. The meta-analysis identified 98 and 360 differentially expressed lncRNAs (DElncRNAs) and PCGs (DEPCGs), respectively, in addition to five differentially expressed miRNAs (DEmiRNAs) identified by small RNA-seq. Co-expression correlation network clustering of DElncRNAs/DEPCGs identified a functionally relevant sub-cluster containing DANCR and SNHG6, with DElncRNAs overlapping with TCGA-GBM output. Analysis of the pathways associated with these DElncRNAs and DEPCGs revealed an association with a novel cell death pathway, ferroptosis. Thus, our results confirm the involvement of ferroptosis in glioblastoma pathophysiology and present several candidates for further research Glioblastoma is a devastating grade IV glioma with poor prognosis. Identification of predictive molecular biomarkers of disease progression would substantially contribute to better disease management. In the current study, we performed a meta-analysis of different RNA-seq datasets to identify differentially expressed protein-coding genes (PCGs) and long non-coding RNAs (lncRNAs). This meta-analysis aimed to improve power and reproducibility of the individual studies while identifying overlapping disease-relevant pathways. We supplemented the meta-analysis with small RNA-seq on glioblastoma tissue samples to provide an overall transcriptomic view of glioblastoma. Co-expression correlation of filtered differentially expressed PCGs and lncRNAs identified a functionally relevant sub-cluster containing DANCR and SNHG6, with two novel lncRNAs and two novel PCGs. Small RNA-seq of glioblastoma tissues identified five differentially expressed microRNAs of which three interacted with the functionally relevant sub-cluster. Pathway analysis of this sub-cluster identified several glioblastoma-linked pathways, which were also previously associated with the novel cell death pathway, ferroptosis. In conclusion, the current meta-analysis strengthens evidence of an overarching involvement of ferroptosis in glioblastoma pathogenesis and also suggests some candidates for further analyses.".
- 01GNHR12WYJJ2K6DRHBDE00S59 abstract "Offshore wind farms are constantly growing in many countries around the globe and are becoming responsible for a significant part of electricity generation. Transmission system operators require these sustainable sources to contribute to ancillary services such as frequency containment reserve. Consequently, offshore wind farms are needed to temporarily increase and decrease the active power delivered into the power system to compensate for grid imbalances caused by electricity production and consumption unbalance. This paper studies a wind farm’s optimal coordinated operation strategy, aiming to maximise the overall power production while providing active power control services to the power grid by minimising the wake interactions inside the wind farm. The particle swarm optimisation algorithm is used to decide each wind turbine’s desired control setpoints for the optimal distribution of power reserve among the wind turbines. This strategy reduces the negative effect of wakes caused by the upstream turbines and thus maximises the power reserve and total power production. The first phase of the C-Power Belgian offshore wind farm in the North Sea with six wind turbines is considered to evaluate the performance of the proposed approach. Results demonstrate the effectiveness of the proposed control strategy in different operational conditions.".
- 01GNJBY96CZGX686MMX0N5ET56 abstract "The Oral Corpus of the Atlas Lingüístico-Etnográfico de Colombia (ALEC) is composed of 650 hours of recordings collected during research conducted in Colombia between 1956 and 1983. This corpus includes 45 speaking sample audio files collected in the Amazonian region (departments of Putumayo, Caquetá, Amazonas). These sound files are a representative sample of the Spanish spoken in the region. The Corpus Linguistics and Computational Research Group (grupo de Lingüística de corpus y computacional, LICC) of the Instituto Caro y Cuervo has worked on the systematization of these files using both structural and descriptive metadata. The goal is to make available linguistic conservation material to the academic community, with information that can be exploited for diverse quantitative and/or qualitative analyses from different language levels (phonetic-phonological, morphosyntactic, lexical-semantic, and pragmatic.).".
- 01GNKPHQ2NGW55KKVQPX3D9S0H abstract "Mycotoxins are fungal secondary metabolites produced by numerous fungal species (e.g., Aspergillus, Penicillium, Fusarium, and Alternaria species). The inevitable mycotoxin contamination in food and feed has been recognized as a serious global issue for human and animal health. Human and animal exposure to mycotoxin in developing countries, like Iran, is found to be more vulnerable as regulatory implementations are not being perfectly followed due to several factors such as the ignorance of manufacturers and high expense of food laboratory control. In the current work, a literature review has been conducted on mycotoxin contamination in Iranian food, feed, and human biological fluids covering the last 20 years (2002 to 2022). The collected data included commodity type, mycotoxin type, number of samples, region/province, method of detection, and the detected concentrations. These data were processed and analysed to provide a summary of the incidence and contamination levels of foodborne mycotoxins in Iran. Although data on aflatoxin M1 (in dairy products such as milk), aflatoxin B1, and total aflatoxins (in nuts, dried fruits, and cereals), ochratoxin A (in dried fruits), and patulin (in juices) exist, data on other main mycotoxins are scarce to non-existent. For emerging mycotoxins, there is still a need to conduct survey studies to profile their presence in Iranian food and feed. The impact of climate change on toxigenic fungi and mycotoxins must also be investigated to endure the safety of exported as well as local marketed food in Iran. KEY WORDS: aflatoxins; climate change; mycotoxins exposure; food safety; ochratoxin A".
- 01GNKXMRR9WWCFBD3VDCPN6Y3D abstract "Mycotoxins are among the most alarming food and feed contaminants threatening human and animal health. Since the discovery of aflatoxins in the 1960s, our knowledge about mycotoxins increased dramatically: biological syntheses have been unravelled; myriad analytical detection methods were developed; surveys in different matrices were conducted; investigations into toxicities took place; several methods for control have been tested; and legislative debates to protect the public from their toxic effects continue. Based on that, hundreds of review articles were published to summarize different areas in the mycotoxin field, including their contamination per country or per region. However, mycotoxin contamination in the Arab world, which includes 22 countries in Africa and Asia, have not been specifically reviewed. To this end, the present work has been conducted to review the contamination of mycotoxins in the Arab world to identify the main knowledge gaps needed to enhance the safety of food and feed. Our search, using several keywords, covered all the (non-)indexed publications written in English or Arabic or French. To the best of our knowledge, a total number of 306 papers were published between 1977 and 2021, focusing on the natural occurrence of mycotoxins in different matrices, which fall under one of 14 different categories (animal feed; animal products; baby food; cereals; cereal by-products; dairy products; legumes and pulses; nuts; spices; fruits and vegetables; juices and drinks; biomarkers; oils; and others). The relevant information (e.g., detected mycotoxins; number of samples; concentrations; method of detection) were extracted, processed and visualized using Microsoft Excel, R, GraphPad Prism, and RAWGraphs. The main results are presented as follows: i) research on mycotoxins has increased over the years, however the accumulated data on their occurrences are scarce to non-existent in some countries and regions; ii) state-of-the-art technologies on mycotoxin detection are not well implemented; neither are contemporary multi-mycotoxin detection strategies in the Arab world, showing the need for capacity-building initiatives; iii) mycotoxin profiles differ among food and feed categories, as well as between human biofluids. An overview will be presented relying on visualization for an easy take home message delivery. Furthermore, the current legislations in the Arab countries will be discussed in relation to the occurrence of mycotoxins in the Arab world.".
- 01GNKZF3JZ2XQSSXPTZYPDQJSV abstract "A wide range of environmental contaminants are potentially toxic to animals. This includes mycotoxins, pesticides, heavy metals, dioxins, and other environmental chemicals. Animals are exposed to these toxic contaminates mainly via feed and drink inducing variable deleterious effects including hepatotoxicity, nephrotoxicity, neurotoxicity, genotoxicity, immunosuppression, etc. Many of these chemicals are persistent leading to build up of high concentrations in the environment. Residual accumulation of these toxic chemicals in the animal edible tissue represents a potential health hazard to humans. Despite the great success in developing analytical tools for their detection, as well as investigating their toxic mechanisms, still some remain unclear along with those related to the “emerging contaminants”. Moreover, the combined toxicity of chemical mixtures yet to be studied, especially under chronic exposure. Finally, development of effective strategies regarding biomonitoring, remediation, and protective medication are required to control the health hazards of such contaminants. In this Research Topic, we invite all researchers in this field to contribute and share with the readers the most important achievements of their research work. This Research Topic encourages the submission of manuscripts that explore themes such as (but not limited to): - Exploring the toxic mechanisms implicated in environmental chemicals-induced toxicity in animals and fish. - Study the impact of exposure to environmental chemicals on animal health and production. - Determination of the residual levels of environmental chemicals in food, feed, and water. - Effective strategies to limit the adverse effects of these contaminants on animal health through the use of applicable adsorbents, antioxidants, prebiotics, probiotics, etc. - Toxic mechanisms associated with environmental chemicals-induced toxicity. - Biomonitoring and residue analyses. - Remediation and protective medication.".
- 01GNKZZB1G0W4RPRW4QMT09WQY abstract "Communication technology enables employees to be constantly connected at the cost of potentially blurring the boundaries between work and private life, which can be detrimental to their well-being. The present study utilised a quantitative diary approach (N = 269 employees, N = 1256 data points) to provide further evidence on the association between telepressure and ruminative thoughts within boundary-crossing contexts (i.e., including work-related behaviour and cognitions during leisure time as well as private-related behaviour and cognitions at work). On a day-to-day level, we examined if context-incongruent telepressure had a positive effect on context-incongruent affective rumination through context-incongruent message-based communication behaviour. Multilevel analyses supported our hypothesised mediation models. Altogether, findings reveal that quickly replying towards messages or its related cognition (i.e., telepressure) may result in a resource-draining experience in terms of affective rumination within both boundary-crossing contexts. Theoretical and practical implications as well as future research avenues are discussed.".
- 01GNP5WSZ3KP6HN54A5B9QAB4X abstract "In this paper, for the first time, a damage assessment technique for a high-rise concrete structure is presented. This structure has sixteen stories, a total height of 57 m and its total long and short spans are 33 m. Especially, this structure has the appearance of shear wall and core wall elements, which has not yet investigated in the literature. For this purpose, a new Finite Element (FE) model updating technique is proposed based on the development of a successful program, which makes a link between SAP2000 commercial software and MATLAB program. This program allows the user to create a continuous two-way data exchange between SAP2000 and MATLAB. Thus, the process of parameters updating in the FE model in SAP2000 can be implemented by com-mand in the code instead of by point-click procedures. The process of structural damage assessment is then secured by inverse methods. This method will be handled by a bio-inspired meta-heuristic optimization algo-rithm, namely Termite Life Cycle Optimizer (TLCO), which is proposed by the authors recently. The parameters in TLCO are fixed. Therefore, it is not necessary for the user to set the initial parameters, which is an effective strategy compared to other algorithms. The results obtained in this study show a significant improvement in the damage identification of large-scale structures.".
- 01GNPHVZC3M8DNFS1Y691SA26M abstract "Glioblastoma multiforme (GBM) is the most aggressive type of glioma, displaying atypical glycosylation pattern that may modulate signaling pathways involved in tumorigenesis. Lectins are glycan binding proteins with antitumor properties. The present study was designed to evaluate the antitumor capacity of the Dioclea reflexa lectin (DrfL) on glioma cell cultures. Our results demonstrated that DrfL induced morphological changes and cytotoxic effects in glioma cell cultures of C6, U-87MG and GBM1 cell lines. The action of DrfL was dependent upon interaction with glycans, and required a carbohydrate recognition domain (CRD), and the cytotoxic effect was apparently selective for tumor cells, not altering viability and morphology of primary astrocytes. DrfL inhibited tumor cell migration, adhesion, proliferation and survival, and these effects were accompanied by activation of p38(MAPK) and JNK (p46/54), along with inhibition of Akt and ERK1/2. DrfL also upregulated pro-apoptotic (BNIP3 and PUMA) and autophagic proteins (Atg5 and LC3 cleavage) in GBM cells. Noteworthy, inhibition of autophagy and caspase-8 were both able to attenuate cell death in GBM cells treated with DrfL. Our results indicate that DrfL cytotoxicity against GBM involves modulation of cell pathways, including MAPKs and Akt, which are associated with autophagy and caspase-8 dependent cell death.".
- 01GNQJDHY3JYHF6PE3PEQZBNE8 abstract "Japaridze’s provability logic (GLP) has one modality [n] for each natural number and has been used by Beklemishev for a proof theoretic analysis of Peano arithmetic (PA) and related theories. Among other benefits, this analysis yields the so-called Every Worm Dies (EWD) principle, a natural combinatorial statement independent of PA. Recently, Beklemishev and Pakhomov have studied notions of provability corresponding to transfinite modalities in GLP. We show that indeed the natural transfinite extension of GLP is sound for this interpretation and yields independent combinatorial principles for the second-order theory ACA of arithmetical comprehension with full induction. We also provide restricted versions of EWD related to the fragments IΣ_n of PA. In order to prove the latter, we show that standard Hardy functions majorize their variants based on tree ordinals.".