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- 01GJ2ZY0E1JM6RDFAQV9K0H44R classification A1.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R date "2022".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R language "eng".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R type journalArticle.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R hasPart 01GJ3030C0093NY3BPY22FFPKP.pdf.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R subject "Medicine and Health Sciences".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R doi "10.1080/15412555.2022.2039608".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R issn "1541-2555".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R issn "1541-2563".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R issue "1".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R volume "19".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R abstract "Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with variable mortality risk. The aim of our investigation was to validate a simple clinical algorithm for long-term mortality previously proposed by Burgel et al. in 2017. Subjects with COPD from two cohorts, the Swedish PRAXIS study (n = 784, mean age (standard deviation (SD)) 64.0 years (7.5), 42% males) and the Rotterdam Study (n = 735, mean age (SD) 72 years (9.2), 57% males), were included. Five clinical clusters were derived from baseline data on age, body mass index, dyspnoea grade, pulmonary function and comorbidity (cardiovascular disease/diabetes). Cox models were used to study associations with 9-year mortality. The distribution of clinical clusters (1-5) was 29%/45%/8%/6%/12% in the PRAXIS study and 23%/26%/36%/0%/15% in the Rotterdam Study. The cumulative proportion of deaths at the 9-year follow-up was highest in clusters 1 (65%) and 4 (72%), and lowest in cluster 5 (10%) in the PRAXIS study. In the Rotterdam Study, cluster 1 (44%) had the highest cumulative mortality and cluster 5 (5%) the lowest. Compared with cluster 5, the meta-analysed age- and sex-adjusted hazard ratio (95% confidence interval) for cluster 1 was 6.37 (3.94-10.32) and those for clusters 2 and 3 were 2.61 (1.58-4.32) and 3.06 (1.82-5.13), respectively. Burgel's clinical clusters can be used to predict long-term mortality risk. Clusters 1 and 4 are associated with the poorest prognosis, cluster 5 with the best prognosis and clusters 2 and 3 with intermediate prognosis in two independent cohorts from Sweden and the Netherlands.".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author 04778CDA-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author BCC58358-1F47-11E4-ABD6-473CB5D1D7B1.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author F497BC5E-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:2f000731-5a35-44f3-83d0-309ba35872aa.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:5e5dcdaf-7722-4c7e-aa61-fca107e56beb.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:6be27302-6a89-4bf7-870f-9e05a1f73cf2.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:703d1960-c8b5-4f2d-94e7-ad025918256e.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:9b985ead-9ca5-44ae-ba42-2a89ee145e42.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:9e784fe2-1fb1-4a7d-81f4-90548ef6b4bd.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:a04ab5ff-2106-4362-b0bc-6c3a08cb7d65.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:b112e119-3d9a-401a-8ec9-2bdde55fd954.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:e8c19035-a599-4047-841d-ff0014d04dce.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R author urn:uuid:f20cb9fb-d94a-44c8-9766-f04edb9c48f0.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R dateCreated "2022-11-17T14:29:52Z".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R dateModified "2024-07-09T14:34:28Z".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R name "Validation of clinical COPD phenotypes for prognosis of long-term mortality in Swedish and Dutch cohorts".
- 01GJ2ZY0E1JM6RDFAQV9K0H44R pagination urn:uuid:ac3aebcc-279e-4af8-a0da-e2be23e0e0df.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R sameAs LU-01GJ2ZY0E1JM6RDFAQV9K0H44R.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R sourceOrganization urn:uuid:5ffa302d-1d51-4cb3-abfe-de12403fef70.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R sourceOrganization urn:uuid:966e5b80-402f-4841-84ea-ee174e0407da.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R sourceOrganization urn:uuid:a47fd191-ee8f-44c2-bd58-bc602c670c6e.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R sourceOrganization urn:uuid:f430de4e-cb1e-4f6a-b352-ebd66320cd5e.
- 01GJ2ZY0E1JM6RDFAQV9K0H44R type A1.